Danxin Wang, M.D., Ph.D.
Associate Professor
On This Page
About Danxin Wang
Dr. Wang received her MD degree from Fudan University Medical School and her Ph.D from the Academy of Military Medical Science in Beijing. She did postdoctoral training at the University of California San Francisco. She was a Research Assistant Professor at Ohio State University, Department of Cancer Biology and Genetics and Associate Director of Center for Pharmacogenomics prior to joining the University of Florida.
Dr. Wang’s research interests are the discovery of genetic biomarkers for personalized drug therapy. She has discovered many functional regulatory variants in genes related to drug therapy in the areas of cardiovascular diseases, mental diseases and drug dependence. Some of these functional variants are currently included in biomarker testing panels to predict drug response.
Funded by NIH R01 and R35 awards, Dr. Wang’s current research is to understand factors controlling the expression of cytochrome P450 drug metabolizing enzymes (CYPs) in the liver. Using recently developed cutting edge functional genetics/genomics approaches, the research will focus on understanding what genetic, epigenetic and non-genetic factors may contribute to CYPs variability, with the goal to identify biomarker predicting enzyme activity of CYPs for guiding personalized drug therapy.
Dr. Wang has served as an Associate Editor of “European Journal of Pharmaceutical Sciences” and was on editorial Board of “Journal of Pharmacogenomics and Pharmacoproteomics”. She has also served as grant reviewer for NIH.
Teaching Profile
Courses Taught
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PHA6427 – Pharmacogenetics of Drug Metabolism
College of Pharmacy
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PHA6935 – Selected Topics in Pharmacy
College of Pharmacy
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PHA6134 – Foundations in Precision Medicine: Genomic Technologies
College of Pharmacy
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PHA5930 – Sem Pharm Research
College of Pharmacy
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PHA6910 – Supervised Research
College of Pharmacy
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PHA6449 – Pharmacogenomic and Genomic Data Analysis
College of Pharmacy
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PHA7979 – Advanced Research
College of Pharmacy
Research Profile
Areas of Interest
- Drug Metabolism
- Gene expression
- Pharmacogenetics
- Pharmacogenomics
Publications
Academic Articles
Grants
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Cardiovascular Adverse Events Related to Aromatase Inhibitors in Breast Cancer
Active
- Role:
- Co-Investigator
- Funding:
- FL BREAST CANCER FOU
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Expression genetics of pharmacogenes
Active
- Role:
- Principal Investigator
- Funding:
- NATL INST OF HLTH NIGMS
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Translational candidate-gene studies of simvastatin-induced myopathy in African Americans
- Role:
- Principal Investigator
- Funding:
- OHIO STATE UNIV via NATL INST OF HLTH NIMHD
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Expression Genetics of CYP3A Drug Metabolizing Enzymes
- Role:
- Principal Investigator
- Funding:
- NATL INST OF HLTH NIGMS
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Genetic determinants of ACEI prodrug activation
- Role:
- Principal Investigator
- Funding:
- UNIV OF MICHIGAN via NATL INST OF HLTH NHLBI
Education
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Ph.D.
Academy of Military Medical Sciences
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M.S.
Fudan University Medical School
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M.D.
Fudan University Medical School
Contact Details
- Business:
- (352) 273-7673
- Business:
- danxin.wang@ufl.edu
- Business Mailing:
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PO Box 100486
GAINESVILLE FL 32610 - Business Street:
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1345 CENTER DRIVE MSB ROOM PG-05B
GAINESVILLE FL 326100001