Arashdeep Singh

Arashdeep Singh,

Postdoctoral Associate

Department: Pharmacodynamics
Business Phone: (352) 273-7706
Business Email:


Early Career Best Presentation Award at CICMD Research Showcase
2019 · University of Florida Center for Integrative Cardiovascular and Metabolic Disease (USA)
Eyes High Learn from the Best Award
2018 · University of Calgary (Canada)
Feeding Tomorrow Graduate Scholarship
2017 · Feeding Tomorrow Foundation and Institute of Food Technologists (USA)
NSERC CREATE Scholarship for Integrated Training Program in Infectious Diseases, Food Safety and Public Policy
2016-2017 · University of Saskatchewan (Canada)
Early Career Best Abstract Award
2016 · The Obesity Society (USA)
Eyes High Up Your Game Award
2015 · University of Calgary (Canada)
Feeding Tomorrow Graduate Scholarship
2015 · Feeding Tomorrow Foundation and Institute of Food Technologists (USA)
Gerald L. (Jerry) Weber- Cosmopolitan International Club of Calgary Graduate Scholarship (Diabetes Research Award)
2015 · University of Calgary (Canada)
Eyes High Top Flight Awards
2014-2017 · University of Calgary (Canada)
Rolls-Simons Travel Award
2014 · The Obesity Society (USA)
Keystone Symposia Scholarship
2011 · Keystone Symposia on Molecular and Cellular Biology (USA)
Gold Medal and Academic Excellence Scholarship
2011 · Thapar Institute of Engineering and Technology (India)

Research Profile

My research focuses on investigating how long-term consumption of palatable high-fat, high-sugar foods causes alternations in the gut-brain neural circuitry and the endogenous function of the gut-vagus-brain axis to promote cardiovascular malfunction, diabetes and obesity. By utilizing a combination of neural circuit mapping, in vivo live cell imaging, chemogenetics and optogenetics approaches, my research aims to unravel how ensembles of neural networks that receive anatomical and functional inputs from the gut are dysregulated in metabolic disease states.

Open Researcher and Contributor ID (ORCID)


Areas of Interest
  • Cardiometabolic Disease
  • Diabetes
  • Exercise and nutrition
  • Gut Microbiome
  • Integrative neuroscience
  • Metabolic syndrome
  • Metabolism
  • Obesity prevention and treatment


Central and peripheral GLP-1 systems independently suppress eating
Nature Metabolism. 3(2):258-273 [DOI] 10.1038/s42255-021-00344-4. [PMID] 33589843.
Demystifying functional role of cocaine- and amphetamine-related transcript (CART) peptide in control of energy homeostasis: A twenty-five year expedition.
Peptides. 140 [DOI] 10.1016/j.peptides.2021.170534. [PMID] 33757831.
Intact vagal gut-brain signalling prevents hyperphagia and excessive weight gain in response to high-fat high-sugar diet.
Acta physiologica (Oxford, England). 231(3) [DOI] 10.1111/apha.13530. [PMID] 32603548.
Blunted Vagal Cocaine- and Amphetamine-Regulated Transcript Promotes Hyperphagia and Weight Gain.
Cell reports. 30(6):2028-2039.e4 [DOI] 10.1016/j.celrep.2020.01.045. [PMID] 32049029.
Gut microbiota sPARk vagus nerve excitation
The Journal of Physiology. 598(11):2043-2044 [DOI] 10.1113/jp279763.
Innovations in Geroscience to enhance mobility in older adults.
Experimental gerontology. 142 [DOI] 10.1016/j.exger.2020.111123. [PMID] 33191210.
Whey protein and its components lactalbumin and lactoferrin affect energy balance and protect against stroke onset and renal damage in salt-loaded and high-fat fed male spontaneously hypertensive stroke-prone rats
Journal of Nutrition. 150(4):763-774 [DOI] 10.1093/jn/nxz312. [PMID] 31879775.
Host genetics and diet composition interact to modulate gut microbiota and predisposition to metabolic syndrome in spontaneously hypertensive stroke-prone rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(6):6748-6766 [DOI] 10.1096/fj.201801627RRR. [PMID] 30821497.
Low-Protein Diets with Fixed Carbohydrate Content Promote Hyperphagia and Sympathetically Mediated Increase in Energy Expenditure.
Molecular nutrition & food research. 63(21) [DOI] 10.1002/mnfr.201900088. [PMID] 31365786.
Methionine Restriction Partly Recapitulates the Sympathetically Mediated Enhanced Energy Expenditure Induced by Total Amino Acid Restriction in Rats.
Nutrients. 11(3) [DOI] 10.3390/nu11030707. [PMID] 30917593.
Tryptophan restriction partially recapitulates the age-dependent effects of total amino acid restriction on energy balance in diet-induced obese rats.
The Journal of nutritional biochemistry. 65:115-127 [DOI] 10.1016/j.jnutbio.2018.12.006. [PMID] 30685580.
Dietary Tryptophan Restriction Dose-Dependently Modulates Energy Balance, Gut Hormones, and Microbiota in Obesity-Prone Rats.
Obesity (Silver Spring, Md.). 26(4):730-739 [DOI] 10.1002/oby.22136. [PMID] 29504260.
Inulin fiber dose-dependently modulates energy balance, glucose tolerance, gut microbiota, hormones and diet preference in high-fat-fed male rats.
The Journal of nutritional biochemistry. 59:142-152 [DOI] 10.1016/j.jnutbio.2018.05.017. [PMID] 30005919.
Peptide YY mediates the satiety effects of diets enriched with whey protein fractions in male rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(2):850-861 [DOI] 10.1096/fj.201700519RR. [PMID] 29042449.
Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance.
Proceedings of the National Academy of Sciences of the United States of America. 115(29):7605-7610 [DOI] 10.1073/pnas.1802251115. [PMID] 29967158.
Dietary lactalbumin and lactoferrin interact with inulin to modulate energy balance in obese rats.
Obesity (Silver Spring, Md.). 25(6):1050-1060 [DOI] 10.1002/oby.21840. [PMID] 28437574.
Whey Protein Components – Lactalbumin and Lactoferrin – Improve Energy Balance and Metabolism.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-09781-2. [PMID] 28855697.
Diets enriched in whey or casein improve energy balance and prevent morbidity and renal damage in salt-loaded and high-fat-fed spontaneously hypertensive stroke-prone rats.
The Journal of nutritional biochemistry. 37:47-59 [DOI] 10.1016/j.jnutbio.2016.07.011. [PMID] 27611102.
Low protein diets produce divergent effects on energy balance.
Scientific reports. 6 [DOI] 10.1038/srep25145. [PMID] 27122299.
Effective conversion of industrial starch waste to L-Lactic acid by Lactococcus lactis in a dialysis sac bioreactor
Annals of Microbiology. 64(3):1447-1452 [DOI] 10.1007/s13213-013-0754-2.
Probiotic characterization of potential hydrolases producing Lactococcus lactis subsp. lactis isolated from pickled yam.
International journal of food sciences and nutrition. 65(1):53-61 [DOI] 10.3109/09637486.2013.832175. [PMID] 24020495.
Survival of probiotic strains in non-dairy Indian spice condiment exhibiting cholesterol reducing properties
Food Science and Biotechnology. 21(5):1309-1315 [DOI] 10.1007/s10068-012-0172-4.


Doctor of Philosophy (Ph.D.)
2018 · University of Calgary (Canada)
Bachelor of Technology
2012 · Thapar Institute of Engineering and Technology (India)

Contact Details

(352) 273-7706