Rodrigo Cristofoletti

Rodrigo Cristofoletti, Ph.D.

Assistant Professor

Department: Pharmaceutics
Business Phone: (407) 313-7050
Business Email:

About Rodrigo Cristofoletti

Rodrigo Cristofoletti, Ph.D., joined the University of Florida in 2019 as research assistant professor in the Center for Pharmacometrics and Systems Pharmacology (Orlando) in the Department of Pharmaceutics. He received his B.S. in Pharmaceutical Sciences from the University of Sao Paulo, Brazil in 2004. Dr. Cristofoletti received his Ph.D. summa cum laude from the Johann Wolfgang Goethe University (Frankfurt am Main, Germany) under the supervision of Dr. Jennifer Dressman in 2017. The Therapeutic Equivalence Department of the Brazilian Drug Regulatory Agency (ANVISA) has been Dr. Cristofoletti’s place of employment for the last 14 years. While there, his research on oral drug absorption has helped in building scientific foundations for generic policies within Brazilian jurisdiction.

Dr. Cristofoletti received the Simcyp Academic Most Informative and Scientific Report 2017 Award for his research on translational modeling strategies to establishing an in vitro-in vivo link. He serves as a member of the Special Interest Group on BCS and Biowaiver of the International Pharmaceutical Federation (FIP) and a member of the Brazilian Pharmacopoeia.

Research Profile

Dr. Cristofoletti’s research focuses on leveraging quantitative methods and modeling to optimize drug development and modernize regulatory review processes. A major emphasis has been on integrating in vitro-in vivo extrapolation with physiologically-based and PK/PD models to address interpatient variability in drug absorption and pharmacological response. He is also interested in investigating the kinetics of target site drug distributions in disease states under the overarching umbrella of quantitative systems pharmacology. Dr. Cristofoletti published more than 35 peer-reviewed articles in highly respected journals in the pharmaceutics field as well as 5 book chapters.


Jun 2020 ACTIVE
Assessing the impact of highly prevalent chronic comorbidities on antifungal treatment in elderly patients: disease-based modeling as a candle in the dark
SIMULATIONS PLUS · Principal Investigator


2017 · Johann Wolfgang Goethe University

Contact Details

(407) 313-7050