UF medicinal chemists report promising results from a study that may help in the battle against MRSA, tuberculosis and other infectious pathogens.
Robert Huigens, Ph.D., an assistant professor of medicinal chemistry, has re-engineered the structure of vincamine, a plant-derived compound and administered it to mice, successfully reducing their morphine-seeking behaviors. The American Chemical Society featured the study on the May cover of the Journal of Medicinal Chemistry.
Rob Huigens, Ph.D., an assistant professor of medicinal chemistry, and other UF researchers have re-engineered the structure of vincamine, a plant-derived compound, so that it reduces morphine-seeking behaviors in mice.
UF researchers discovered their compounds induced rapid iron starvation through a series of experiments using novel compounds known as halogenated phenazines, or HPs.
Known as the Maximizing Investigators’ Research Award, the grant will fund several of Huigens’ research projects, including efforts to develop compounds that will eliminate bacterial biofilm-associated infections.
Led by principal investigator, Rob Huigens, Ph.D., an assistant professor of medicinal chemistry, the grant aims to establish a drug discovery pipeline to generate and identify new small molecules that possess anticancer activities.
A University of Florida research team investigating biofilm-eradication has landed on the cover of the Feb. 16 issue of ChemBioChem.
A novel strategy developed by UF Health researchers has yielded several promising compounds to fight inflammation and diseases such as colorectal cancer.
The honor is the highest recognition of teaching excellence given within the College of Pharmacy.
Medicinal chemists at the College of Pharmacy recently discovered a series of organic compounds that can kill dangerous bacterial biofilms.