February 17, 2025
38th Annual Research Showcase Presenters
Oral Competition
Maureen Keller-Wood Junior Graduate Student Research
| Time | Presenter | Title | Department |
|---|---|---|---|
| 2:00 PM | Jean Malave Rivera | Impact of Social Determinants of Health on Outcomes in P2Y12 Inhibitor-Treated Post-PCI Patients | Pharmacotherapy & Translational Research |
| 2:15 PM | Md Abu Siddique | Machine Learning-Assisted Gene Signatures in Acinar Cells: Insights into Pancreatic Cancer Subtypes | Pharmaceutics |
| 2:30 PM | Chien-Yu (Irene) Tseng | Impact of Obstructive Sleep Apnea on Treatment Selection for Type 2 Diabetes Mellitus | Pharmaceutical Outcomes & Policy |
Impact of Social Determinants of Health on Outcomes in P2Y12 Inhibitor-Treated Post-PCI Patients
Jean Malave Rivera
Machine Learning-Assisted Gene Signatures in Acinar Cells: Insights into Pancreatic Cancer Subtypes
Md Abu Siddique
Impact of Obstructive Sleep Apnea on Treatment Selection for Type 2 Diabetes Mellitus
Chien-Yu (Irene) Tseng
William J. Millard Senior Graduate Student Research: Basic Sciences
| Time | Presenter | Title | Department |
|---|---|---|---|
| 2:45 PM | Breanne Freeman | Relevance of NNAL Bioactivation: Analyses of Hydrolyzed Adducts in Different NNK Exposure Conditions | Medicinal Chemistry |
| 3:00 PM | Haylee R. Hammond | Opioid Agonists with Low Intrinsic Efficacy as Opioid Sparing Agents | Pharmacodynamics |
| 3:15 PM | Michelle Kuntz | Mitragynine During Pregnancy: Investigating Behavioral and Pharmacokinetic Impacts in Rat Models | Pharmaceutics |
Relevance of NNAL Bioactivation: Analyses of Hydrolyzed Adducts in Different NNK Exposure Conditions
Breanne Freeman
Opioid Agonists with Low Intrinsic Efficacy as Opioid Sparing Agents
Haylee R. Hammond
Mitragynine During Pregnancy: Investigating Behavioral and Pharmacokinetic Impacts in Rat Models
Michelle Kuntz
Julie A. Johnson Senior Graduate Student Research: Clinical Sciences
| Time | Presenter | Title | Department |
|---|---|---|---|
| 3:45 PM | Eissa Jafari | Effect of Hypertension Control Levels on Cardiovascular Outcomes in Patients with Dementia | Pharmacotherapy & Translational Research |
| 4:00 PM | Philip Melchert | An In Vitro Evaluation of Commonly Used Botanical Extracts on CES1 Catalytic Activity | Pharmacotherapy & Translational Research |
| 4:15 PM | Samia Shabnaz | Causal Role of Bile Acids in Carfilzomib-Related CVAEs: A Mendelian Randomization Study | Pharmacotherapy & Translational Research |
Effect of Hypertension Control Levels on Cardiovascular Outcomes in Patients with Dementia
Eissa Jafari
An In Vitro Evaluation of Commonly Used Botanical Extracts on CES1 Catalytic Activity
Philip Melchert
Causal Role of Bile Acids in Carfilzomib-Related CVAEs: A Mendelian Randomization Study
Samia Shabnaz
Postdoctoral Scholar Research
| Time | Presenter | Title | Department |
|---|---|---|---|
| 4:30 PM | Larissa Costa de Almeida | Translating Chemical Genomics of Apratoxins into Combination Therapy for Colorectal Cancer | Medicinal Chemistry |
| 4:45 PM | Sanghoon Kang | Leveraging AI and PyRadiomic for MR Biomarkers of Bone Fragility in Duchenne Muscular Dystrophy | Pharmaceutics |
| 5:00 PM | Aneesha Nath | Genetic Variants in PK/PD Pathway Genes of Standard Chemotherapy Regimen Predicts Outcome in AML | Pharmacotherapy & Translational Research |
Translating Chemical Genomics of Apratoxins into Combination Therapy for Colorectal Cancer
Larissa Costa de Almeida
Leveraging AI and PyRadiomic for MR Biomarkers of Bone Fragility in Duchenne Muscular Dystrophy
Sanghoon Kang
Single Nucleotide Polymorphisms Located in PK/PD Pathway Genes of Standard AML Chemotherapy Regimen
Aneesha Nath
Poster Competition
Poster Presentations
| # | Presenter | Research Title | Department |
|---|---|---|---|
| 1 | Karly Caples | CTS Team Approach to Investigate Skeletal Muscle Diseases and Therapeutics in a Donor-Derived 3D MPS | Pharmacodynamics |
| 2 | Alexis Smith | PROTAC-Induced Degradation of the METTL3/METTL14 Complex to Alter m6A mRNA Abundance in AML | Medicinal Chemistry |
| 3 | Kalynn Turner | Real-time, Voltammetric Co-Detection of Serotonin and Glucose at Carbon-Fiber Microbiosensors | Pharmacodynamics |
| 4 | Vanisa Petriti | Characterization of a Bacterial Cytochrome P450 for Oxidative Biaryl Coupling | Medicinal Chemistry |
| 5 | Hillary Jean-Pierre | Advancing Therapeutic Development: Plant-Derived Extracellular Vesicles for Drug Delivery. | Pharmaceutics |
| 6 | Peter Ramdhan | Molecular Dynamics and Quantum Mechanics of CYP2C19 Variants: Effects on Clopidogrel Activation | Medicinal Chemistry |
| 7 | Kajal Gupta | Developing a State of the Art Virtual Bioequivalence Platform for Ibuprofen | Pharmaceutics |
| 8 | Kuntala Dey | Design and Synthesis of AAK1 PROTAC Degraders | Medicinal Chemistry |
| 9 | Nina Erwin | Nanoparticle Based Endogenous Cargo Loading of Extracellular Vesicles for Therapeutic Delivery | Pharmaceutics |
| 10 | Campbell Eckhardt | AI-Supported Mutagenesis of MysD to Synthesize Green Sunscreen Mycosporine-Like Amino Acid Analogs | Medicinal Chemistry |
| 11 | Xuefen Yin | Mitigating Bias in Exposure-Response Analysis Methods When Using the Inappropriate Exposure Metrics | Pharmaceutics |
| 12 | Kayleigh Linder | Effects of Developmental Exposure to Firemaster 550 on Dopamine Signaling in Prairie Vole Striatum | Pharmacodynamics |
| 13 | Zijing Xu | Tuning the Organ-Selectivity of mRNA Expression Through Dendrimer-Based Lipid Nanoparticles | Pharmaceutics |
| 14 | Allison Lynch | AB-free Kava Enhances Resilience Against the Adverse Health Effects of Tobacco Smoke in Mice | Medicinal Chemistry |
| 15 | Easton van Luik | Inhibition of 5-HT₂A Receptors Reduces Tic-Like Behaviors in Two Murine Tourette Syndrome Models | Pharmacodynamics |
| 16 | Seyedehalaleh Anvar | Senescence, an Index to Monitor Cancer Therapy Response | Medicinal Chemistry |
| 17 | Zachary Greenberg | AI-driven Molecular Engineering Methods to Advance Extracellular Vesicle Precision Medicine | Pharmaceutics |
| 18 | Yuzhao Zhang | Gatorator: A Tool for Lead Optimization and Application in Developing Heparanase Inhibitors. | Medicinal Chemistry |
| 19 | Samantha Ali | Extracellular Vesicles Reveal 3D Tissue Physiology and Aging Associated Transcriptomic Network | Pharmaceutics |
| 20 | Meng-Lun Hsieh | Design and Expression of Dimeric Y3 by Yeast Surface Display Against TACAs | Medicinal Chemistry |
| 21 | Zhishen Wang | Exploring Human Heparanase Activity with Synthetic Glycans | Medicinal Chemistry |
| 22 | Alexandria Senetra | Pharmacokinetic Profiles of Paynantheine and its Diastereomer, Isopaynantheine, in Rats | Pharmaceutics |
| 23 | Jeremiah Batucan | Discovery, Synthesis, and Biological Activity of Welwicyclamide A from a Cultured Cyanobacterium | Medicinal Chemistry |
| 24 | Ariana Figueroa | Osteopontin-Mediated Reprogramming of CNS Microglia in Response to Peripheral Inflammation | Pharmacodynamics |
| 25 | Abelardo D. Montalvo | Discovering a Distil Enhancer SNP that Regulates CYP2C9 Expression to Refine CYP2C9 Biomarker Panels | Pharmacotherapy & Transl Res |
| 26 | Bassma Eltanameli | Assessment of Orally Inhaled Drugs Permeability Across In Vitro Pulmonary Epithelial Cell Models | Pharmaceutics |
| 27 | Emma Ellis | New Anticancer Kahalalides from a Marine Cyanobacterium | Medicinal Chemistry |
| 28 | Yi-Hua Chiang | Translational Modeling of Mitragynine for Opioid Use Disorder Treatment Development | Pharmaceutics |
| 29 | Brian Molina Diaz | Remote-Controlled Actuation of 3D Magnetic Scaffolds for Mimicking Lung Respiratory Strain | Pharmaceutics |
| 30 | Nadine Alshakhshir | Mechanisms Governing Dendritic Oxytocin Release in the PVN | Pharmacodynamics |
| 31 | Morgan Reeves | Investigating the Impact of CXCR6 on Wnt/B-catenin Signaling and Sorafenib Resistance Development | Pharmacodynamics |
| 32 | Johnathan Somers | An Activatable Probe for Detection and Imaging of Heparanase Activity via Bioluminescence | Medicinal Chemistry |
| 33 | Shu-Hao Hsu | Species-Specific Metabolism of CM699: In Vitro to In Vivo Extrapolation | Pharmaceutics |
| 34 | Tam Pham | New Chlorinated Pyrrolidines from Marine Cyanobacteria: Isolation, Synthesis, and Biology | Medicinal Chemistry |
| 35 | Yifan Wang | AB-Free Kava Suppressed Tobacco Smoke Induced CREB Phosphorylation in the Cerebellum in Mice | Medicinal Chemistry |
| 36 | Shelby Green | Dual Acting Sigma Receptor & Dopamine Transporter Ligands as Treatment for Cocaine Use Disorder | Medicinal Chemistry |
| 37 | Jordan Stokes | Gene Therapy of Computationally Designed IL-10 Mutants for Inflammatory Bowel Disease | Pharmaceutics |
| 38 | Eman Gabal | The Impact of Commitment Devices on Academic Performances | Pharmacotherapy & Transl Res |
| 39 | Hanna Corron | Investigating Key Biomarkers and Factors Influencing Relapse in Multiple Sclerosis | Pharmaceutics |
| 40 | Olivia Roberson | Combat MRSA Bacteremia: Harness Daptomycin and Ceftaroline with Effective Source Control | Pharmacotherapy & Transl Res |
| 41 | Abigail Douglas | Evaluating Prescribing Patterns of Sulfonylureas with other Glucose Lowering Medications | Pharmacy Education & Practice |
| 42 | Alejandra Nogueira | Lack of Differential Gene Expression of Ryanodine Receptor 2 in a Pre-Clinical Model of Heart Failure | Pharmacotherapy & Transl Res |
| 43 | Nghi Nguyen | A Minimal Physiologically-Based Pharmacokinetic Model of Biotin in Healthy Adults | Pharmaceutics |
| 44 | Andrés López | Evaluating PCI Stent Properties and Cardiovascular Outcomes in Patients on Dual Antiplatelet Therapy | Pharmacotherapy & Transl Res |
| 45 | Eleanna Faust | Establishing the True Effectiveness of Pharmacist-Led CMRs on Healthcare Outcomes: A Scoping Review | Pharm Outomes & Policy |
| 46 | Stephanie Hernandez | Pharmacogenomics in Practice: Literature Review of Pharmacist-Led Graduate Student, Clinical Programs Across the U.S. | Pharmacotherapy & Transl Res |
| 47 | Antonella Oettl | Rapid Long-Read Sequencing for Actionable Genomic and Pharmacogenomic Profiling in Acute Leukemia | Pharmacotherapy & Transl Res |
| 48 | Isabella Ico | Impact of De-escalation Timing on Mortality in MRSA Bacteremia Treated with Daptomycin-Ceftaroline | Pharmacotherapy & Transl Res |
| 49 | Sarah Kallas | Analyzing Alzheimer's Pathogenesis and Therapeutics: A Basis for Model-Informed Drug Development | Pharmaceutics |
| 50 | Stephany Diaz | Role of Chemokines Receptors in Improvement of Opioid Therapy | Pharmacodynamics |
| 51 | Ana Dogan | Functionalizing AuNPs for Enhanced Extracellular Vesicle Cargo Loading for Therapeutic Delivery | Pharmaceutics |
| 52 | Feha Shahalam | Integrated Analysis Of CIC::DUX4 Fusion Identifies Novel Upregulation Of The POLE Gene | Pharmacotherapy & Transl Res |
| 53 | Leif Holmstrom | Evaluating Generative Models for Bioluminescent Enzyme Engineering | Medicinal Chemistry |
| 54 | Kathleen Rish | Antimicrobial Pharmacokinetic Studies in Sea Turtles: A Review | Pharmacy Education & Practice |
| 55 | Arlen Gyden | ArlVPI: A Novel Machine-Learning-Informed Platform for Assessing Somatic Variant Pathogenicity | Pharmacotherapy & Transl Res |
| 56 | Jingzhou Yang | Investigating the Human Lung Mediated Metabolism of Cocaine | Pharmaceutics |
| 57 | Anjali Paragji | In Silico Analysis of CDKN2A Pathway Dependencies in Ewing Sarcoma | Pharmacotherapy & Transl Res |
| 58 | Josephine Raeuscher | Investigating Steroid Hormone Changes After Short-term High-Dose Exposure in Healthy Subjects | Pharmacotherapy & Transl Res |
| 59 | Wenxi Huang | Effect of Neighborhood Deprivation on Racial Disparities in Heart Failure Outcomes | Pharm Outomes & Policy |
| 60 | Brian Gawronski | Baseline Characteristics for the Trial of Preemptive Pharmacogenetics in Underserved Patients | Pharmacotherapy & Transl Res |
| 61 | Matthew Taylor | Characterizing Promoter TA Repeats and Searching for Population-Specific Regulatory SNPs in UGT1A1 | Pharmacotherapy & Transl Res |
| 62 | Clemence Boivin-Champeaux | Development of a Quantitative Systems Pharmacology Model for Hepatitis B Virus Infection | Pharmaceutics |
| 63 | Ngoc Thuy Tram Nguyen | Initial Antihypertensive Therapy for UFHealth Patients in the First Year of Hypertension Diagnosis | Pharm Outomes & Policy |
| 64 | Kimia Zandbiglari | Enhancing Suicide Detection in Electronic Health Records: A Multi-Label NLP Framework | Pharm Outomes & Policy |
| 65 | Anthony Gebhart | Dose Optimization of Cefazolin on Adult Cardiac Surgery with Cardiopulmonary Bypass | Pharmaceutics |
| 66 | Leonardo da Costa Xavier | Enhancing Clopidogrel Efficacy Through Gene-Drug Interaction PBPK Modeling | Pharmaceutics |
| 67 | Chanakan Jenjai | Effectiveness of Injectable Versus Oral Medication For HIV Pre-exposure Prophylaxis | Pharm Outomes & Policy |
| 68 | Satyavardhan Rao Nittu | Genetic Variants Predicting Febrile Neutropenia in Induction I Therapy for Pediatric AML | Pharmacotherapy & Transl Res |
| 69 | Hung-Kai (Henry) Chen | Risk of Pregnancy Loss after Prenatal Exposure to Doxycycline: A Retrospective Cohort Study | Pharm Outomes & Policy |
| 70 | Priscila Yamamoto | Maternal-Fetal PBPK Model to Predict Drug-Drug Interaction with Ritonavir at the Placental Level | Pharmaceutics |
| 71 | Chloe Jian | Use of Advanced Therapies for IBD is Cardioprotective Compared to 5-ASA in Medicare IBD Patients | Pharm Outomes & Policy |
| 72 | Qingchen Zhang | Evaluating Reversible Inhibitory Drug-Drug Interactions | Pharmacotherapy & Transl Res |
| 73 | Amirah Alnahdi | Evaluating MACE Risk of Advanced Therapies in IBD: A Systematic Review and Meta-Analysis | Pharm Outomes & Policy |
| 74 | Mohammad Yaseliani | Lightweight Graph Convolutional Network for Predicting Mortality in Coronary Artery Disease Patients | Pharm Outomes & Policy |
| 75 | Rylie Flohr | GWAS Identifies Associations with Methotrexate Response in Pulmonary Sarcoidosis | Pharmacotherapy & Transl Res |
| 76 | Mai Abdelmageed | A Simulation Tool for Dose Selection of Intrathecal Antisense Oligonucleotides in Pediatrics | Pharmaceutics |
| 77 | Raed Alshammari | Methylation Analysis Reveals Epigenetic Mechanisms in Carfilzomib Cardiotoxicity in MM Patients. | Pharmacotherapy & Transl Res |
| 78 | Celeste Ewig | A Systematic Review of Risk Management Strategies: Evaluating the Evidence to Support Future Policies | Pharm Outomes & Policy |
| 79 | Wen Wen | Doxycycline and Congenital Malformation: A Retrospective Claims-based Signal Detection Study | Pharm Outomes & Policy |
| 80 | Maryam Al Saeed | ABCD Score: A Real-World Study on Predicting Clopidogrel Effectiveness after PCI | Pharmacotherapy & Transl Res |
| 81 | Fatemeh Mehrabi | A Review of Drug-Drug Interactions involving Medical Cannabis in Older Adults | Pharm Outomes & Policy |
| 82 | Sulafa Al Sahlawi | PBPK Modeling of Depot Medroxyprogesterone Acetate: Predicting Drug Release and Systemic Exposure | Pharmaceutics |
| 83 | Kayla Smith | Trends in Telehealth Uptake in Patients with Hypertension Pre-and Post-COVID-19 | Pharm Outomes & Policy |
| 84 | Ryanne Mulligan | Comparative Protein Profiling of Acute Myeloid Leukemia | Pharmacotherapy & Transl Res |
| 85 | Cameron Humerickhouse | Protein Binding: Static Solutions to a Dynamic Problem May Mislead Drug Development and Regulation | Pharmaceutics |
| 86 | Priyanka Kulkarni | Sequence Symmetry Analysis to Detect Calcium Channel Blocker-induced Prescribing Cascades | Pharm Outomes & Policy |
| 87 | Sabiha Rahman Mim | Assay Validation and PK Modeling of Antimalarial Drug Combination in Mice: Insights & Challenges | Pharmaceutics |
| 88 | Sumaya Abuloha | A Budget Impact Analysis (BIA) of Novel Treatments for Spinal Muscular Atrophy | Pharm Outomes & Policy |
| 89 | Manoj Gundeti | Advanced Simultaneous Pharmacokinetic-Pharmacodynamic Model for Safety Evaluation in Rats | Pharmaceutics |
| 90 | Naifah Alshameri | Epigenetic Regulation of Drug and Disease-Related Genes Impact Outcomes in Pediatric AML | Pharmacotherapy & Transl Res |
| 91 | Omar Elashkar | Incorporating Bioanalytical Data in Population Pharmacokinetics to Explain Residual Variability | Pharmaceutics |
| 92 | Yanning Wang | Risk of Prenatal Exposure to Teratogenic Medications: A Study of Two US Population-Based Cohorts | Pharm Outomes & Policy |
| 93 | Pareeta Kotecha | Association Between Preoperative GLP-1 RA Use and Postoperative Respiratory Complications | Pharm Outomes & Policy |
| 94 | Shu Niu | Cost-Effectiveness of GLP-1 RA Plus SGLT2i Versus SGLT2i In Patients with Chronic Kidney Disease | Pharm Outomes & Policy |
| 95 | Abhishek Gour | ADME Profiling of Aristoquinoline as a Selective α3β4 nAChR Inhibitor for Cocaine Use Disorder | Pharmaceutics |
| 96 | Yi Liu | Development of Hydrazide-based HDAC8 Selective PROTACs | Medicinal Chemistry |
| 97 | Mona Alshahawey | Genome-Wide Association Study (GWAS) of Hypertension: Insights From the All of Us Research Program | Pharmacotherapy & Transl Res |
| 98 | Mallesh Kathe | Discovery and Total Synthesis of Novel Chlorinated Natural Products from Marine Cyanobacteria | Medicinal Chemistry |
| 99 | Zuo Ding | A Microfluidic Droplet-based Electroporation System for Scalable Extracellular Vesicle Drug Loading | Pharmaceutics |
| 100 | Wenqiang Cui | Designing Haloalkane Dehalogenase Variants With Generative AI: Accelerating the SN2 Reaction | Medicinal Chemistry |
| 101 | Jae Choi | Evaluation of Opioid Overdose Rate Associated with Access to Proper Disposal Sites | Pharm Outomes & Policy |
| 102 | Xiaoshu Pan | Enabling Extracellular Vesicles for Targeted Delivery Using Deep Learning Models-Designed Ligands | Pharmaceutics |
| 103 | Irina Fofanova | Determination of Provider Characteristics Who Refer to MyRx | Pharmacotherapy & Transl Res |
| 104 | Qiaosi Tang | MGMG: Cell Morphology-Guided Molecule Generation with Chemical Knowledge and Natural Language | Medicinal Chemistry |
| 105 | Melody Walker | Contraceptives Effect on Bone Density | Pharmaceutics |
| 106 | Olfa Trejos Kweyete | Supportive Care Medication Use in Metastatic Colorectal Cancer using SEER-Medicare Database | Pharmacotherapy & Transl Res |
| 107 | Dipesh Dhakal | Biosynthesis of Dolastatin 10, a Prototype for Multiple Approved Cancer Drugs | Medicinal Chemistry |
| 108 | Andrew Brock | RNA Sequencing at Single Vesicle Resolution to Elucidate Extracellular Vesicle Heterogeneity | Pharmaceutics |
| 109 | Eswarakumar Aratikatla | Synthesis of CoraFluor Complexes for Studying Molecular Interactions | Medicinal Chemistry |
| 110 | Jovica Todorov | Advancing Electroanalytical Tools and Techniques for Real-Time Monitoring of Opioid Neuropeptides | Pharmacodynamics |
| 111 | Amira Soliman | Optimizing Pediatric Dosing of Spironolactone: A PBPK Model Approach | Pharmaceutics |
| 112 | Phani Krishna Parcha | Synergistic Effect of Trifluridine and PARPi on TP53-Mutated AML | Pharmacotherapy & Transl Res |
Thank You
Thank you to all of our sponsors and contributors to this year’s Research Showcase!