February 5-6, 2024
37th Annual Research Showcase
The UF College of Pharmacy's Annual Research Showcase has grown in size and stature over the years to become one of the college's signature events. It has laid the foundation for many UF College of Pharmacy alumni to launch successful careers in academia, the pharmaceutical industry, with governmental agencies and more.
Welcome
A letter from the Dean
"This yearโs event features more than 110 poster presentations and an exceptional lineup of speakers for the oral competition."
Itโs my honor to welcome you to the University of Florida College of Pharmacyโs 37th Annual Research Showcase. As one of the signature events in our college, Research Showcase continues to expand each year. This yearโs event features more than 110 poster presentations and an exceptional lineup of speakers for the oral competition. All of us in the UF College of Pharmacy take great pride in the research contributions made by our students and trainees, and Research Showcase provides a meaningful way to share their findings with our college and the broader scientific community.
In keeping with the tradition of welcoming an accomplished scientist as our keynote speaker, the UF College of Pharmacy is delighted to host Angela Kashuba, B.Sc.Phm, Pharm.D, dean of the University of North Carolina Eshelman School of Pharmacy. Dr. Kashuba joined the UNC faculty in 1997 and served as chair of the division of pharmacotherapy and experimental therapeutics from 2015 to 2019. For the last four years, she has led UNCโs Eshelman School of Pharmacy while also maintaining a research program focused on optimizing antiretroviral pharmacology in the treatment, prevention and eradication of HIV infection. As a distinguished scientist, Dr. Kashuba has authored more than 300 manuscripts, secured over $25 million in research funding and earned numerous national awards. In todayโs presentation, she will explore mass spectroscopy imaging, offering insights into its application in HIV treatment, prevention and care. It should be an enlightening topic for our faculty, students and trainees, as we host one of academic pharmacyโs most esteemed leaders.
Congratulations to all our students and trainees presenting this week. I also want to extend a special thank you to the faculty and staff who have supported their efforts. The UF College of Pharmacy has experienced a phenomenal year in research, as evidenced by our annual research funding increasing 25% in new data submitted to the American Association of Colleges of Pharmacy. The 37th Annual Research Showcase provides a fantastic platform to honor and celebrate all our collective achievements.
Peter W. Swaan, Ph.D., M.Pharm.
Dean and Professor, UF College of Pharmacy
KEYNOTE Address
Angela Kashuba, B.Sc.Phm., Pharm.D., DABCP, FCP
Angela Kashuba, B.Sc.Phm., Pharm.D., DABCP, FCP, is the John A and Margaret P McNeill, Sr. Distinguished Professor and Dean of the UNC Eshelman School of Pharmacy. She has been on faculty at the University of North Carolina at Chapel Hill since 1997 and served as the Chair of the Division of Pharmacotherapy and Experimental Therapeutics from 2015 to 2019.
Dr. Kashuba serves as Director of the UNC Center for AIDS Research Clinical Pharmacology and Analytical Chemistry Core and leads a research laboratory focused on optimizing antiretroviral pharmacology in the treatment,
prevention, and eradication of HIV infection. Her laboratory has authored over 300 manuscripts and received over $25 million in research funding. She is the recipient of the 2020 ASCPT Rawlsโ Palmer Progress in Medicine Award, 2017 ACCP (Pharmacology) Honorary Fellowship Award, and 2017 ACCP (Pharmacy) Therapeutic Frontiers Lecture Award. Dr. Kashuba received her Bachelorโs in Pharmacy Degree from the University of Toronto and her Doctor of Pharmacy Degree from SUNY Buffalo. She completed a residency at Womenโs College Hospital and a clinical pharmacology research fellowship at the Clinical Pharmacology Research Center at Bassett Healthcare in
Cooperstown, NY.
Schedule of Events
Monday, February 5, 2024
9-11 a.m.
Postdoctoral and Pharm.D. Student Poster Competition
HPNP Atrium
12-2 p.m.
Graduate Student Poster Competition A
HPNP Atrium
3-5 p.m.
Graduate Student Poster Competition B
HPNP Atrium
Tuesday, February 6, 2024
10-11 a.m.
Postdoctoral Scholar Oral Competition
HPNP Auditorium
1-3:30 p.m.
Graduate Student Oral Competition
HPNP Auditorium
4-5 p.m.
Keynote Speaker Address: Dr. Angela Kashuba
HPNP Auditorium
5-5:30 p.m.
Showcase Awards Ceremony
HPNP Auditorium
5:30-6:30 p.m.
Reception
BMS Atrium
Poster Competition
Judges
| Category | Department | Judge |
|---|---|---|
| PharmD & UnderGraduate Students, Session A | Pharmacotherapy and Translational Research | John Allen |
| PharmD & UnderGraduate Students, Session A | Pharmacodynamics | Erin Bruce |
| PharmD & UnderGraduate Students, Session A | Pharmaceutical Outcomes and Policy | Amie Goodin |
| PharmD & UnderGraduate Students, Session B | Pharmaceutical Outcomes and Policy | Earl Morris |
| PharmD & UnderGraduate Students, Session B | Pharmaceutical Outcomes and Policy | Rachel Reise |
| PharmD & UnderGraduate Students, Session B | Medicinal Chemistry | Margaret James |
| Postdoctoral Trainee, Session A | Pharmaceutical Outcomes and Policy | Masoud Rouhizadeh |
| Postdoctoral Trainee, Session A | Medicinal Chemistry | Zhixing Wu |
| Postdoctoral Trainee, Session A | Pharmacotherapy and Translational Research | Nathan Seligson |
| Postdoctoral Trainee, Session B | Medicinal Chemistry | Xingui Liu |
| Postdoctoral Trainee, Session B | Pharmaceutics | Jinmai Jiang |
| Postdoctoral Trainee, Session B | Pharmacotherapy and Translational Research | Danxin Wang |
| Graduate Student, Basic Sciences: Cancer | Pharmacotherapy and Translational Research | David Deremer |
| Graduate Student, Basic Sciences: Cancer | Pharmacodynamics | Maddalena Parafati |
| Graduate Student, Basic Sciences: Cancer | Pharmaceutics | Sihong Song |
| Graduate Student, Basic Sciences: CNS | Pharmaceutics | Mei He |
| Graduate Student, Basic Sciences: CNS | Medicinal Chemistry | Zhixing Wu |
| Graduate Student, Basic Sciences: CNS | Medicinal Chemistry | Xingui Liu |
| Graduate Student, Basic Sciences: New Techniques | Medicinal Chemistry | Yanjun Li |
| Graduate Student, Basic Sciences: New Techniques | Medicinal Chemistry | Wenjun Xie |
| Graduate Student, Basic Sciences: New Techniques | Pharmacotherapy and Translational Research | Mohammad Gbadamosi |
| Graduate Student, Clinical: Drug Metabolism | Pharmacotherapy and Translational Research | Mohammad Gbadamosi |
| Graduate Student, Clinical: Drug Metabolism | Pharmaceutics | Francine Azeredo |
| Graduate Student, Clinical: Drug Metabolism | Pharmacotherapy and Translational Research | Khoa Nguyen |
| Graduate Student, Clinical: Outcomes & Utilization | Pharmacodynamics | Maddalena Parafati |
| Graduate Student, Clinical: Outcomes & Utilization | Medicinal Chemistry | Gustavo Seabra |
| Graduate Student, Clinical: Outcomes & Utilization | Pharmacotherapy and Translational Research | Caitrin McDonough |
| Graduate Student, Clinical: Chronic Diseases | Medicinal Chemistry | Sushobhan Mukhopadhyay |
| Graduate Student, Clinical: Chronic Diseases | Pharmacodynamics | Lihui Yuan |
| Graduate Student, Clinical: Chronic Diseases | Pharmaceutics | Sihong Song |
Submissions
| Research Category | Poster Number | Author Name | Research Title |
|---|---|---|---|
| Graduate Student Research: Basic and Translational Science: Cancer | 1 | Breanne Freeman | Potential of Kava in Reducing Lung Cancer Risk: Mechanism-Based Biomarker Discovery and Analysis |
| Graduate Student Research: Basic and Translational Science: Cancer | 2 | Richard Marrero | GWAS Identifies Variants Associated with Measurable Residual Disease Response in Pediatric AML |
| Graduate Student Research: Basic and Translational Science: Cancer | 3 | Zachary Rabinowitz | Activatable Fluorogenic Probe for Two-photon Imaging of Heparanase-1 |
| Graduate Student Research: Basic and Translational Science: Cancer | 4 | Chen Zhou | Exploring Degradation of Intrinsically Disordered Protein YAP induced by PROTACs |
| Graduate Student Research: Basic and Translational Science: Cancer | 5 | Corey Perkins | Inhibition of Pancreatic Acinar Ductal Metaplasia by Novel YAP/TAZ Inhibitor, CV-4-26 |
| Graduate Student Research: Basic and Translational Science: Cancer | 6 | Naifah Alshameri | DNA Methylation of Ara-C, Daunorubicin, Etoposide PK/PD Genes and pediatric AML Clinical Outcomes |
| Graduate Student Research: Basic and Translational Science: Cancer | 7 | Zhihang Shen | Discovery of PRMT5 Inhibitors |
| Graduate Student Research: Basic and Translational Science: Cancer | 8 | Kuntala Dey | Synthesis of a Plausible LATS1/2 Kinase Agonist |
| Graduate Student Research: Basic and Translational Science: Cancer | 9 | Brian Molina Diaz | Magnetic Actuator-Enabled 3D Porous Scaffolds for Mimicking Lung Tumor Constructs |
| Graduate Student Research: Basic and Translational Science: Cancer | 10 | Alexis Smith | PROTAC-induced Degradation to Target Aberrant m6A mRNA Modifications in Acute Myeloid Leukemia |
| Graduate Student Research: Basic and Translational Science: Cancer | 11 | Allison Lynch | One-week Kava Dietary Supplementation Increases Urinary N- and O-glucuronides of NNAL In Smokers |
| Graduate Student Research: Basic and Translational Science: Cancer | 12 | Satyavardhan Rao Nittu | Relapse-Enriched Gene Expression Signature of Prognostic Relevance in Pediatric AML |
| Graduate Student Research: Basic and Translational Science: Cancer | 13 | Kevon Jolly | In Situ Engineering of Tumor-Infiltrating Macrophages Through Dendrimer-Based Lipid Nanoparticles |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 14 | Qingchen Zhang | Investigating Inhibition Effects of Cannabis Smoke Condensate on Cytochrome P450 in Human Lung S9 |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 15 | Michelle Kuntz | A Pharmacokinetic and Pharmacodynamic Evaluation of Mitragynine, a Kratom Alkaloid, in Pregnant Rats |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 16 | Huilin Tang | GLP-1RAs and Risk of Parkinsonโs Disease in U.S. Older Adults with T2D: A Population-Based Study |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 17 | Nadine Alshakhshir | Extrasynaptic NMDA Receptors Expressed by Magnocellular Oxytocin Neurons in Mouse PVN |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 18 | Farzana Islam Adiba | medLlama2-Enhancing Performance of Social Determinants of Health Discovery for Postpartum Depression |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 19 | Tam Pham | Total Synthesis and Biological Evaluation of Lyngbyapeptin A from a Marine Cyanobacterium |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 20 | Shelby Green | Synthesis & Biological Evaluation of Dual Acting SR & DAT Ligands for Treatment of Cocaine Misuse |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 21 | Eissa Jafari | Predictors of Alzheimerโs Disease and Related Dementia in Hypertension Population |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 22 | Ariana Figueroa | Osteopontin-Mediated Reprogramming of CNS Microglia Following Induction of Peripheral Inflammation |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 23 | Jessica Mamallapalli | Yangonin in Kava: a ฮฒ-Adrenergic Receptor Negative Allosteric Modulator with a Slow Mode of Action |
| Graduate Student Research: Basic and Translational Science: CNS Disorders | 24 | Todd Sahagian | Aging Increases CCh Induced Currents Supporting Persistent Firing in BLA Principal Neurons |
| Graduate Student Research: Basic Science: Innovative new techniques | 25 | Vanisa Petriti | Chemical Synthesis and Interconversion of Fusaric Acid Derivatives |
| Graduate Student Research: Basic Science: Innovative new techniques | 26 | Nina Erwin | Enhanced Proteolysis Targeting Chimeras Loading and Delivery Through Extracellular Vesicles |
| Graduate Student Research: Basic Science: Innovative new techniques | 27 | Emma Ellis | Discovery of Taveuniamides L-M and Pharmacological Characterization of Taveuniamide F |
| Graduate Student Research: Basic Science: Innovative new techniques | 28 | Priscila Yamamoto | Dose Optimization of Carvedilol in Post-Roux-en-Y Gastric Bypass: A Population PK/PD Link Approach |
| Graduate Student Research: Basic Science: Innovative new techniques | 29 | Eli Levit | Birch Reduction As a Ring Distortion Platform For the Re-Engineering of Indole Alkaloid Bioactivity |
| Graduate Student Research: Basic Science: Innovative new techniques | 30 | Kajal Gupta | Assessing the In Vitro Performance ID-Cap System for Improved Patients Compliance |
| Graduate Student Research: Basic Science: Innovative new techniques | 31 | Kimia Zandbiglari | Leveraging Large Language Models to Identify Suicidal Behaviors from Electronic Health Records |
| Graduate Student Research: Basic Science: Innovative new techniques | 32 | Samantha Ali | Unraveling MultiOmic Signaling Pathways: Extracellular Vesicles in Muscle for Nanomedicine in Space |
| Graduate Student Research: Basic Science: Innovative new techniques | 33 | Jabed Al Faysal | Explainable Machine Learning Approach to Predict Buprenorphine Discontinuation Risk in OUD Patients |
| Graduate Student Research: Basic Science: Innovative new techniques | 34 | Samantha Rakela | FosTRAP for Targeting Stress-Sensitive Neuronal Ensembles in the Ventromedial Prefrontal Cortex |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 1 | Matthew Taylor | Testing Transcription Activity of UGT1A1 Promoter TA Repeat Polymorphisms Using Reporter Gene Assays |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 2 | Yi-Hua Chiang | Translational Development of Mitragynine Using Physiologically Based Pharmacokinetic Model |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 3 | Philip Melchert | An In Vitro Evaluation of Botanical Extracts on CES1 Catalytic Activity |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 4 | Alexandria Senetra | Preclinical Pharmacokinetic Study of Delta-8-Tetrahydrocannabinol |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 5 | Xuefen Yin | Applying the PBPK Modeling to Interpret Carbamazepine Nonlinear PKs and its Induction Potential |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 6 | Abelardo D. Montalvo | Identification of Functional Regulatory Variants of CYP2C9 in African Americans |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 7 | Bassma Eltanameli | Predicting Pulmonary Absorption and In Vitro Tissue Retention of Orally Inhaled Tobramycin |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 8 | Jean Malave | Risk Score Comparison for Atherothrombotic Events in Clopidogrel Treated Patients |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 9 | Dain Chun | Unraveling Tramadol Dosing Needs in Patients with Diabetes Using PK/PD Modeling |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 10 | Maryam Al Saeed | Impact of the CKD-EPIcr 2021 Equation on ABCD-GENE Score Determination in Patients Who Underwent PCI |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 11 | Sulafa Al Sahlawi | Predicting the Potential for Cannabidiol-Drug Interactions Using Model-Based Approaches |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 12 | Raed Alshammari | Genome-Wide DNA Methylation Analysis Reveals Pattern of Medication-Related Osteonecrosis of the Jaw |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 13 | Omar Elashkar | Population Pharmacokinetic Modeling For Kavain: A Pilot Study in Healthy Volunteers |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 14 | Samia Shabnaz | Metabolomic Biomarkers for Carfilzomib-related Cardiovascular Events in Multiple Myeloma Patients |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 15 | Cameron Thomas | Evaluation of Clinical Outcomes Among Black vs Non-Black Patients After PCI and CYP2C19 Genotyping |
| Graduate Student Research: Clinical and Translational Science: Drug Metabolism | 16 | Mai Abdelmageed | Optimal Design of a Clinical Pharmacokinetic Study with Salicylic Acid in Pregnancy |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 17 | Yanning Wang | Antihypertensive Utilization Patterns Among Pregnant Persons with Pre-existing Hypertension |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 18 | Zijing Xu | Tuning the Organ-Selectivity of mRNA Through Dendrimer-Based Lipid Nanoparticles |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 19 | Shailina Keshwani | Analgesic Use and Presence of Hypertension Among Medicare Beneficiaries with Incident Osteoarthritis |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 20 | Shu Niu | Assessing the Concentration of Spending and Share of Specialty Drug Spending in Medicare Part D |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 21 | Jieqiang Zhou | Pharmacokinetics of Enrofloxacin and Florfenicol in the Giant Danio |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 22 | Celeste Ewig | Secular Trends and Determinants of Hepatitis C Virus Testing during Pregnancy: 2010-2021 |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 23 | Matthew Muschett | Describing Average Daily THC Doses by Indication in Floridaโs Medical Marijuana Use Registry |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 24 | Huili Chen | A Model-Based Meta-analysis of Breakthrough Bleeding in Women Using Hormonal Contraceptives |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 25 | Ying Lu | Newer Glucose-Lowering Drugs and Risk of Suicide: A Meta-Analysis of Randomized Outcome Trials |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 26 | Morgan Reeves | Investigation of CXCR6 Involvement in Sorafenib Resistance Development |
| Graduate Student Research: Clinical Science: Drug Outcomes and Utilization | 27 | Guido Huisman | Examining The Psychoactive Differences Between Kratom Strains |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 28 | Hung-Kai (Henry) Chen | Efficacy of IL-1 or IL-6 Inhibitors in Patients with Juvenile Idiopathic Arthritis |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 29 | Clรฉmence Boivin-Champeaux | Establishment of a Disease Progression Model for the Hepatitis B Virus |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 30 | Alaa Alshehri | A Systematic Review of CEAs of Gene Therapy Treatments for Hemophilia Type A and B |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 31 | Kayla Smith | High-Throughput Screening Detects Thiazide-Induced Prescribing Cascades |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 32 | Rylie Flohr | Ryanodine Receptor 1 Polymorphisms are Associated with Cardiac Function in Heart Failure |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 33 | Sumaya Abuloha | Cancer Drug Price Increases Cannot be Explained by Efficacy or Certainty of Evidence Improvements |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 34 | Fanxing Du | The Impact of De-escalating Antihypertensive Drugs: A Secondary Analysis of the SPRINT |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 35 | Brian Gawronski | Preferences and Willingness to Pay for Pharmacogenetic Testing in Medically Underserved Populations |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 36 | Julia Yang | Chronic Liver Disease is Associated with Greater Risk of Readmission in Patients with Heart Failure |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 37 | Shyam Ramesh | Time to Event Modeling to Predict Age of End-Stage Renal Disease for Patients with ADTKD |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 38 | Asinamai Ndai | Analyzing Factors Affecting Length of Emergency Department Stay in Patients with Hemophilia |
| Graduate Student Research: Clinical Science: Outcomes in Chronic Diseases | 39 | Priyanka Kulkarni | Impact of CDC Recommendation on Hepatitis C Treatment Use among Pregnant Women in the United States |
| PharmD/Undergrad (A) | 1 | Ashley Stultz | HIV PrEP Care Continuum in Outpatient Settings: A Systematic Review with Meta-Analysis |
| PharmD/Undergrad (A) | 2 | Phuong Ton | Engineering a Bacterial Nitroreductase to Improve its Metabolism of the Anti-Cancer Prodrug CB1954 |
| PharmD/Undergrad (A) | 3 | Julia Hunter | High-Throughput Sequence Symmetry Analysis to Detect ACE Inhibitor-Induced Prescribing Cascades |
| PharmD/Undergrad (A) | 4 | Hanna Schultz | Defining Clinical Success: MRSA Bacteremia Patients Treated with Daptomycin and Ceftaroline |
| PharmD/Undergrad (A) | 5 | Julia Hetzel | Synthesis of Analogues of Small Ubiquitin-Related Modifier Interacting Motifs |
| PharmD/Undergrad (A) | 6 | Kyle Lam | Use of REV-ERB Ligands to Prevent Muscle Disuse Atrophy |
| PharmD/Undergrad (A) | 7 | Nghi Nguyen | An Increase in International Normalized Ratio in Patients on Warfarin Infected with COVID-19 |
| PharmD/Undergrad (A) | 8 | Paige Rhein | Transition of Care in a Geriatric Primary Care Setting: A Pilot Program |
| PharmD/Undergrad (A) | 9 | Eman Gabal | Secondary Genomic Landscape Of CIC::DUX4 Fusion Sarcomas |
| PharmD/Undergrad (A) | 10 | Tanner Beachy | High-throughput Sequence Symmetry Analysis to Detect ARB Induced Prescribing Cascade |
| PharmD/Undergrad (B) | 11 | Zachary Hamm | Genetic Variants Associated with Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients |
| PharmD/Undergrad (B) | 12 | Matthew Todd | Machine Learning-Fueled Analysis of Functional Endpoints vs. Imaging Biomarkers in DMD Trials |
| PharmD/Undergrad (B) | 13 | Kayleigh Ballas | The Effect of NNK-Induced Changes in STING Expression on Lung Cancer Tumorigenesis |
| PharmD/Undergrad (B) | 14 | Amanda Morningstar | The Impact of Medication Reconciliations on Blood Pressures at a Free Student-Run Health Clinic |
| PharmD/Undergrad (B) | 15 | Elizabeth Morgan | Physiologically-based Pharmacokinetic Model Analysis of Cocrystalization on Lamotrigine Disposition |
| PharmD/Undergrad (B) | 16 | Ermano Menos | Impact of CYP2C19 Phenoconversion on Drug Metabolism and Patient Outcomes |
| PharmD/Undergrad (B) | 17 | Salliam Pando | Delta Opioid Receptor Bitopic Ligand VRB86C Produces Biased Partial Agonism and Safer Analgesia |
| PharmD/Undergrad (B) | 18 | Andrรฉs Lรณpez | Association of PON1 Genotype and Clopidogrel Response in Patients Who Underwent PCI: Real-World Data |
| PharmD/Undergrad (B) | 19 | Darla Khouri | Evaluation of Teratogenic Effects of Sulfamethoxazole/Trimethoprim: Comprehensive Literature Review |
| PharmD/Undergrad (B) | 20 | Marion-Ian Javier | Racial Disparity in Cardiovascular Adverse Events of Aromatase Inhibitor Use in Breast Cancer |
| PharmD/Undergrad (B) | 21 | Jing Jie Yu | A Meta-analysis of the Association between Triptan Use and Major Cardiovascular Disease Events |
| Postdoctoral Trainee (A) | 22 | Leandro Pippa | PBPK/PD of Omeprazole and Esomeprazole Treatment in Non-obese, Obese and Post-gastric Bypass |
| Postdoctoral Trainee (A) | 23 | Aneesha Nath | Genetic Variants in PK/PD Pathway Genes of Standard AML Chemotherapy Regimen Predicts Outcome |
| Postdoctoral Trainee (A) | 24 | Nitin Charbe | Forecasting Oral Performance of Amorphous Dispersions with PBPK Modeling & Biorelevant Dissolution |
| Postdoctoral Trainee (A) | 25 | Mallesh Kathe | Total Synthesis of Bioactive Natural Products from Marine Cyanobacteria |
| Postdoctoral Trainee (A) | 26 | Vivek Shastri | Novel Anti-CD33-IgC/CD3 Bispecific Antibody Mediates Potent T Cell Killing of AML Cells |
| Postdoctoral Trainee (A) | 27 | Tatiana Iakovleva | Physiologically Based Model of Urination to Optimize Treatment of Local Bladder Diseases |
| Postdoctoral Trainee (A) | 28 | Dipesh Dhakal | A Synthetic Biology Strategy to Generate Key Building Block for Production of Anticancer Apratoxins |
| Postdoctoral Trainee (A) | 29 | Siva Sankara Chenikkayala | Evaluate pH-Triggered, Sustainable Drug Release for Dendrimer-based Formulation of Immune Modulator |
| Postdoctoral Trainee (A) | 30 | Larissa Costa de Almeida | Translating Chemical Genomics of Apratoxins into Combination Therapy for Colorectal Cancer |
| Postdoctoral Trainee (B) | 31 | Venkata Krishna Kowthavarapu | Mechanistic Modeling of In-Vitro Biopharmaceutic Experiments for a Weakly Dibasic Drug |
| Postdoctoral Trainee (B) | 32 | Amit Mondal | Biosynthetic Characterization of Antibacterial Pyrrolomycins |
| Postdoctoral Trainee (B) | 33 | Phani Krishna Parcha | CRISPR/Cas9 Screen Identifies Response Modulators in CPX-351 and 7+3 Regimens |
| Postdoctoral Trainee (B) | 34 | Churni Gupta | A Quantitative Platform Linking Disease Progression and Clinical Outcomes for Parkinsonโs Disease |
| Postdoctoral Trainee (B) | 35 | Gledys Reynaldo-Fernandez | Strategic Selection of Pegylated rHuEPO Candidates Using a PK/PD Mechanistic Extrapolation Approach |
| Postdoctoral Trainee (B) | 36 | Sofia Kokkaliari | New Depsipeptides from Marine Cyanobacteria and Molecular Targets |
| Postdoctoral Trainee (B) | 37 | Monika Trejos Kweyete | Racial Disparities in Adjunctive Supportive Care Medication Use in Pancreatic Cancer Patients |
| Postdoctoral Trainee (B) | 38 | Amira Soliman | Leveraging Omeprazole PBPK/PD Modeling to Inform DDI Specific Recommendations for Pediatric Labeling |
| Postdoctoral Trainee (B) | 39 | Jeffrey Thinschmidt | Experimental Demonstration of Acetylcholinesterase Inhibitors & Reactivators in Anesthetized Rats |
Oral Competition
Judges
| Category | Department | Judge |
|---|---|---|
| Postdoc | Medicinal Chemistry | Chris Xing |
| Postdoc | Pharmaceutics | Stephan Schmidt |
| Postdoc | Pharmaceutics | Fan Zhang |
| Postdoc | Pharmaceutical Outcomes and Policy | Mikael Svennson |
| Postdoc | Pharmacotherapy and Translational Research | Danxin Wang |
| Grad Students | Medicinal Chemistry | Yousong Ding |
| Grad Students | Pharmaceutics | Tom Schmittgen |
| Grad Students | Pharmaceutics | Cary Mobley |
| Grad Students | Pharmaceutical Outcomes and Policy | Mahmud Hasan |
| Grad Students | Keynote Speaker | Angela Kashuba |
Postdoctoral Scholar
| Time | Presenter | Department | Title |
|---|---|---|---|
| 10:15 AM | Mona Alshahawey | Pharmacotherapy and Translational Research | Characterizing Hypertension in the United States: Insights from the All of Us Research Program |
| 10:30 AM | Sanghoon Kang | Pharmaceutics | Toward Finding Biomarkers for T1D: Building Deep Learning Powered Bioimage Analysis Workflow |
| 10:45 AM | Xiaoshu Pan | Pharmaceutics | Developing Extracellular Vesicles for Genome Editing Treatment of Progressive Dominant Hearing Loss |
Junior Graduate Student Research
| Time | Presenter | Department | Title |
|---|---|---|---|
| 1:15 PM | Haylee R. Hammond | Pharmacodynamics | Negative Allosteric Modulation of ยต-opioid Receptor Blocks Agonist Activity and Enhances Naloxone |
| 1:30 PM | Cameron Humerickhouse | Pharmaceutics | A Physiologically Based Pharmacokinetic Lactation Model for Risk of Infant Exposure to Pregabalin |
| 1:45 PM | Yehua Wang | Pharmaceutical Outcomes and Policy | Assessing the Real-World Effectiveness of Hormonal Contraceptives in Commercial Claims Database |
William J. Millard Senior Graduate Student Basic Science Research
| Time | Presenter | Department | Title |
|---|---|---|---|
| 2:00 PM | Saikat Kumar Poddar | Medicinal Chemistry | Exploring A New Linker Tethering Position on ABT-263 for PROTAC Development |
| 2:15 PM | Bo Sortman | Pharmacodynamics | The Prelimbic Cocaine Self-Administration Acquisition Engram Mediates Well-Trained Cocaine Seeking |
| 2:30 PM | Yuzhao Zhang | Medicinal Chemistry | Lead Optimization via Gatorator: A Case Study on Heparanase Inhibitor |
Julie A. Johnson Senior Graduate Student Clinical Science Research
| Time | Presenter | Department | Title |
|---|---|---|---|
| 2:45 PM | Noor Nahid | Pharmacotherapy and Translational Research | Impact of CYP2D6 Inhibitors on Pain Control by the Opioids |
| 3:00 PM | Nam Nguyen | Pharmacotherapy and Translational Research | CRISPR Screens Identify ADE, GO and Bortezomib Response Modulators Association with Outcomes in pAML |
| 3:15 PM | Nicole Smolinski | Pharmaceutical Outcomes and Policy | Management of Pediatric Acute Otitis Media and Consequences in the United States |
Sponsors
Dean Julie Johnson Clinical and Translational Research Endowment
Dr. Julie Johnson
Oral Presentations
Junior Graduate Student Awards
Dr. Maureen Keller-Wood
Oral Presentations
Dr. Navin S. Goyal
Poster Competition
Dr. Michael & Jill Taylor
Oral Presentations
Basic Science: CNS Disorders
Dr. Yan Li
Poster Competition
Dr. Philip & Patricia Burton
Oral Presentations
Thank You
Thank you to all of our sponsors and contributors to this year’s Research Showcase!