Lihui Yuan, Pharm.D., Ph.D., R.Ph.

Clinical Lecturer

Department: Pharmacodynamics

Business Phone: (352) 294-8594

Business Email: yuanlh@cop.ufl.edu

CV: View Curriculum Vitae

About Lihui Yuan

Lihui Yuan, Pharm.D., Ph.D., joined the University of Florida College of Pharmacy’s department of pharmacodynamics as a clinical lecturer in 2016. She earned her Pharm.D. from the UF College of Pharmacy and a Ph.D. in molecular genetics and microbiology from UF. Her research interests include diabetes, bacterial pathogenesis and hypertension and cardiovascular disease. In her doctorate program, Yuan researched identifying virulence genes of oral bacteria that are related to pathogenesis of periodontal disease. Her recent research with the department of pathology at UF has focused on establishing associations of viral infections and Type 1 diabetes. Yuan has expressed a passion for teaching and patient care, and she believes that the combination of her understanding of basic science and Pharm.D. training will serve her students well.

Research Profile

Diabetes, bacterial pathogenesis, hypertension and cardiovascular disease

Publications

2014

Increased Ifn-Alpha-Producing Plasmacytoid Dendritic Cells (Pdcs) in Human Th1-Mediated Type 1 Diabetes: Pdcs Augment Th1 Responses Through Ifn-Alpha Production

Journal of Immunology. 193(4):1024-1034 [DOI] 10.4049/jimmunol.1303230. [PMID] 24973447.

View on: PubMed Publisher’s Site

2014

C-Abl inhibitor imatinib enhances insulin production by β cells: c-Abl negatively regulates insulin production via interfering with the expression of NKx2.2 and GLUT-2

PLoS One. 9(5) [DOI] 10.1371/journal.pone.0097694. [PMID] 24835010.

View on: PubMed Publisher’s Site

2012

ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy.

Molecular therapy : the journal of the American Society of Gene Therapy. 20(1):28-36 [DOI] 10.1038/mt.2011.155. [PMID] 21792177.

View on: PubMed Publisher’s Site

2011

Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats.

Journal of the renin-angiotensin-aldosterone system : JRAAS. 12(4):456-61 [DOI] 10.1177/1470320311412809. [PMID] 21719524.

View on: PubMed Publisher’s Site

2009

Prevention of Pulmonary Hypertension By Angiotensin-Converting Enzyme 2 Gene Transfer

Hypertension. 54(2):365-371 [DOI] 10.1161/HYPERTENSIONAHA.108.125468. [PMID] 19564552.

View on: PubMed Publisher’s Site

2009

Increased Expression of Ndufa10, a Subunit of Mitochondrial Complex 1, in the Cardiovascular Relevant Brain Regions of the Spontaneously Hypertensive Rat

Hypertension. 54

2009

Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

American journal of respiratory and critical care medicine. 179(11):1048-54 [DOI] 10.1164/rccm.200811-1678OC. [PMID] 19246717.

View on: PubMed Publisher’s Site

2008

Porphyromonas gingivalis htrA is involved in cellular invasion and in vivo survival.

Microbiology (Reading, England). 154(Pt 4):1161-1169 [DOI] 10.1099/mic.0.2007/015131-0. [PMID] 18375808.

View on: PubMed Publisher’s Site

2008

Overexpression of Ace 2 in the Nucleus Tractus Solitarius Improves Baroreflex Function in the Spontaneously Hypertensive Rat

Journal of Hypertension. 26

2008

Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology.

Hypertension (Dallas, Tex. : 1979). 51(3):712-8 [DOI] 10.1161/HYPERTENSIONAHA.107.100693. [PMID] 18250366.

View on: PubMed Publisher’s Site

2008

Aav-Mediated Gene Transfer of Ace2 Protects Retinal Vascular Dysfunction in An Animal Model of Diabetic Retinopathy

Journal of Hypertension. 26

2008

Ace2 Activation Prevents Monocrotaline-Induced Pulmonary Hypertension

Hypertension. 52

2007

The Porphyromonas gingivalis clpB gene is involved in cellular invasion in vitro and virulence in vivo

Fems Immunology and Medical Microbiology. 51(2):388-98 [DOI] 10.1111/j.1574-695X.2007.00326.x. [PMID] 17854400.

View on: PubMed Publisher’s Site

2005

Microarray analysis of quorum-sensing-regulated genes in Porphyromonas gingivalis

Infection and Immunity. 73(7):4146-54 [DOI] 10.1128/IAI.73.7.4146-4154.2005. [PMID] 15972504.

View on: PubMed Publisher’s Site

Education

Pharm.D.

2016 · University of Florida

Ph.D.

2005 · University of Florida

Teaching Profile

Courses Taught

2017-2021

PHA5560 Pathphys-Pt Assess I

2019-2021

PHA6935 Selected Topics in Pharmacy

2020-2021

PHA6563 Pathophysiology of Diseases I

2017-2018,2020-2021

PHA5161L Pract Skills Lab I

2017-2021

PHA5561 Pathphys-Pt Assess II

2018-2019

PHA5732 Year 1 Enhancement

2018-2019

PHA5787C Pt Care 5: Endo

2017-2018

PHA5162L Prac Skills Lab II

Contact Details

Phones:

Business:: (352) 294-8594

Emails:

Business:: yuanlh@cop.ufl.edu