Lihui Yuan

Lihui Yuan, Pharm.D., Ph.D., R.Ph.

Clinical Associate Professor

Department: Pharmacodynamics
Business Phone: (352) 294-8594
Business Email: yuanlh@ufl.edu

About Lihui Yuan

Lihui Yuan, Pharm.D., Ph.D., joined the University of Florida College of Pharmacy’s department of pharmacodynamics as a clinical lecturer in 2016. She was appointed an instructional assistant professor in 2021 and a clinical associate professor in 2023. She earned her Pharm.D. from the UF College of Pharmacy and a Ph.D. in molecular genetics and microbiology from UF. Her research interests include diabetes, bacterial pathogenesis and hypertension and cardiovascular disease. In her doctorate program, Yuan researched identifying virulence genes of oral bacteria that are related to pathogenesis of periodontal disease. Her recent research with the department of pathology at UF has focused on establishing associations of viral infections and Type 1 diabetes. Yuan has expressed a passion for teaching and patient care, and she believes that the combination of her understanding of basic science and Pharm.D. training will serve her students well.

Teaching Profile

Courses Taught
2017-2024
PHA5560 Pathphys-Pt Assess I
2019-2021
PHA6935 Selected Topics in Pharmacy
2020-2024
PHA6563 Pathophysiology of Diseases I
2017-2018,2020-2021
PHA5161L Pract Skills Lab I
2017-2024
PHA5561 Pathphys-Pt Assess II
2018-2019,2021
PHA5732 Year 1 Enhancement
2018-2019,2021-2024
PHA5787C Pt Care 5: Endo
2017-2018,2021
PHA5162L Prac Skills Lab II
2021
PHA5787 Pharmacotherapy 5
2021-2024
PHA6564 Pathophysiology of Diseases II
2022-2024
PHA5784C Pt Care 4: GI and Renal
2022-2024
PHA6508 Systems Physiology and Pathophysiology I
2023-2024
PHA6509 Systems Physiology and Pathophysiology II
2023
PHA5878C Pt Care 3: Cv and Pulm

Research Profile

Diabetes, bacterial pathogenesis, hypertension and cardiovascular disease

Publications

2021
Lactate Dehydrogenase B and Pyruvate Oxidation Pathway Associated With Carfilzomib-Related Cardiotoxicity in Multiple Myeloma Patients: Result of a Multi-Omics Integrative Analysis.
Frontiers in cardiovascular medicine. 8 [DOI] 10.3389/fcvm.2021.645122. [PMID] 33996940.
2014
C-Abl inhibitor imatinib enhances insulin production by β cells: c-Abl negatively regulates insulin production via interfering with the expression of NKx2.2 and GLUT-2.
PloS one. 9(5) [DOI] 10.1371/journal.pone.0097694. [PMID] 24835010.
2014
Increased IFN-α-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-α production.
Journal of immunology (Baltimore, Md. : 1950). 193(3):1024-34 [DOI] 10.4049/jimmunol.1303230. [PMID] 24973447.
2012
ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy.
Molecular therapy : the journal of the American Society of Gene Therapy. 20(1):28-36 [DOI] 10.1038/mt.2011.155. [PMID] 21792177.
2011
Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats.
Journal of the renin-angiotensin-aldosterone system : JRAAS. 12(4):456-61 [DOI] 10.1177/1470320311412809. [PMID] 21719524.
2009
Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.
American journal of respiratory and critical care medicine. 179(11):1048-54 [DOI] 10.1164/rccm.200811-1678OC. [PMID] 19246717.
2009
Increased Expression of Ndufa10, a Subunit of Mitochondrial Complex 1, in the Cardiovascular Relevant Brain Regions of the Spontaneously Hypertensive Rat
Hypertension. 54
2009
Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer.
Hypertension (Dallas, Tex. : 1979). 54(2):365-71 [DOI] 10.1161/HYPERTENSIONAHA.108.125468. [PMID] 19564552.
2008
Aav-Mediated Gene Transfer of Ace2 Protects Retinal Vascular Dysfunction in An Animal Model of Diabetic Retinopathy
Journal of Hypertension. 26
2008
Ace2 Activation Prevents Monocrotaline-Induced Pulmonary Hypertension
Hypertension. 52
2008
Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology.
Hypertension (Dallas, Tex. : 1979). 51(3):712-8 [DOI] 10.1161/HYPERTENSIONAHA.107.100693. [PMID] 18250366.
2008
Overexpression of Ace 2 in the Nucleus Tractus Solitarius Improves Baroreflex Function in the Spontaneously Hypertensive Rat
Journal of Hypertension. 26
2008
Porphyromonas gingivalis htrA is involved in cellular invasion and in vivo survival.
Microbiology (Reading, England). 154(Pt 4):1161-1169 [DOI] 10.1099/mic.0.2007/015131-0. [PMID] 18375808.
2007
The Porphyromonas gingivalis clpB gene is involved in cellular invasion in vitro and virulence in vivo.
FEMS immunology and medical microbiology. 51(2):388-98 [PMID] 17854400.
2006
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR.
Physiological genomics. 27(1):12-9 [PMID] 16788004.
2005
Microarray analysis of quorum-sensing-regulated genes in Porphyromonas gingivalis.
Infection and immunity. 73(7):4146-54 [PMID] 15972504.

Education

Pharm.D.
2016 · University of Florida
Ph.D.
2005 · University of Florida

Contact Details

Phones:
Business:
(352) 294-8594
Emails:
Business:
yuanlh@ufl.edu
Addresses:
Business Mailing:
PO Box 100487
GAINESVILLE FL 32610
Business Street:
MSB P2-33
1600 SW ARCHER RD
GAINESVILLE FL 32610-3003