Bowen Yan

Bowen Yan, Ph.D.

Research Assistant Professor

Department: MD-PHARMACOLOGY / THERAPEUTICS
Business Phone: (352) 273-5906
Business Email: yanbowen@ufl.edu

Research Profile

Dr. Yan researches aging or DNA-damaging related hematological defects and malignancies.

Open Researcher and Contributor ID (ORCID)

0000-0003-4730-6763

Publications

2023
Epigenetic Mechanisms in Hematologic Aging and Premalignant Conditions.
Epigenomes. 7(4) [DOI] 10.3390/epigenomes7040032. [PMID] 38131904.
2021
HDAC1 is required for GATA-1 transcription activity, global chromatin occupancy and hematopoiesis
Nucleic Acids Research. 49(17):9783-9798 [DOI] 10.1093/nar/gkab737. [PMID] 34450641.
2020
Low-frequency TP53 hotspot mutation contributes to chemoresistance through clonal expansion in acute myeloid leukemia.
Leukemia. 34(7):1816-1827 [DOI] 10.1038/s41375-020-0710-7. [PMID] 31988438.
2019
Histone deacetylase inhibitor targets CD123/CD47-positive cells and reverse chemoresistance phenotype in acute myeloid leukemia.
Leukemia. 33(4):931-944 [DOI] 10.1038/s41375-018-0279-6. [PMID] 30291336.
2019
HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice.
Cancer cell. 36(6):645-659.e8 [DOI] 10.1016/j.ccell.2019.10.011. [PMID] 31786140.
2018
CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia.
Blood. 132(8):837-848 [DOI] 10.1182/blood-2017-11-814319. [PMID] 29760161.
2017
Histone deacetylase 1 activates PU.1 gene transcription through regulating TAF9 deacetylation and transcription factor IID assembly.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(9):4104-4116 [DOI] 10.1096/fj.201700022R. [PMID] 28572446.
2017
Histone deacetylase 6 regulates cytokinesis and erythrocyte enucleation through deacetylation of formin protein mDia2.
Haematologica. 102(6):984-994 [DOI] 10.3324/haematol.2016.161513. [PMID] 28255013.

Education

Ph.D.
2012 · China Agriculture University

Contact Details

Phones:
Business:
(352) 273-5906
Emails:
Business:
yanbowen@ufl.edu
Addresses:
Business Mailing:
PO Box 100267
GAINESVILLE FL 32610
Business Street:
UF
GAINESVILLE FL 326100001