Valvanera Vozmediano Esteban

Valvanera Vozmediano Esteban, Ph.D.

Assistant Professor

Department: Pharmaceutics
Business Phone: (407) 313-7052
Business Email: valva@cop.ufl.edu

About Valvanera Vozmediano Esteban

Valvanera Vozmediano, Ph.D., is an assistant professor at the Center of Pharmacometrics & System Pharmacology at University of Florida College of Pharmacy. She has been working as Principal Consultant with Dynakin’s Drug Modeling & Consulting group, and has been the Director of the Research & Development Department of the same company since 2008.

She received her B.S. in pharmacy from the University of Basque Country in Spain in 2006, and earned her Ph.D. in Pharmacology in 2011 at the same university. Her doctorate research was completed at Dynakin with the design of pioneering regulatory standard pediatric investigational plan (PIP) for a new H1 antihistamine drug applying state of the art modeling & simulation (M&S) techniques. Her research activity includes a postdoctoral internship as Marie Curie (B-MOB program) and authorship of peer-reviewed publications. Valvanera is expert in the application of allometric scaling and preclinical MBDD using population PK/PD methods specializing in translational development, mainly for the pediatric field. She has successfully completed several projects in that domain as an industrial consultant in FTIM questions, PIPs, and bridging studies, including support to successful filings for new drug applications. Valvanera is an invited professor for the Master in Drug Development of the University of Basque Country, and she is also a tutor in the International Master of Pediatric Clinical Pharmacology from the Global Research in Pediatric Network of Excellence, or GRIP.

Research Profile

Research interests include:

Model Informed Drug Development for strategic decision making in Special Populations including pediatrics, geriatrics, different ethnicities & rare diseases

Implementation of Pharmacometric Based Regulatory Strategies

Application of Translational Research to Animal Health

Publications

2019
Integrating Drug- and Formulation-Related Properties With Gastrointestinal Tract Variability Using a Product-Specific Particle Size Approach: Case Example Ibuprofen.
Journal of pharmaceutical sciences. 108(12):3842-3847 [DOI] 10.1016/j.xphs.2019.09.012. [PMID] 31539541.

Grants

Jun 2020 ACTIVE
Development of a Physiologically based Pharmacokinetic Model (PBPK) to Inform the Development of a New Nasal Formulation of Epinephrine
Role: Principal Investigator
Funding: ARS PHARMACEUTICALS
Nov 2018 ACTIVE
Development of a Mechanism-Based Drug Disease Trial Model for Parkinsons disease (PD)
Role: Principal Investigator
Funding: MILLENNIUM PHARMACEUTICAL
Nov 2017 ACTIVE
Application of physiologically-based pharmacokinetic models to inform dosing recommendations for hormonal contraceptives co-administered with other medications
Role: Co-Investigator
Funding: GATES FOU, BILL & MELINDA

Education

Ph.D.
2011 · University of Basque Country
B.S.
2006 · University of Basque Country

Teaching Profile

Courses Taught
2019-2021
PHA7979 Advanced Research
2018,2020
PHA6935 Selected Topics in Pharmacy
2020
PHA6910 Supervised Research
2018,2020
PHA6125 Introduction to Quantitative Pharmacology
2019-2020
PHA7980 Research for Doctoral Dissertation
2020-2021
PHA6971 Research for Master’s Thesis
2018-2019
PHA5132 Prin Drug Ther Indiv
2018
PHA5787C Pt Care 5: Endo

Contact Details

Phones:
Business:
(407) 313-7052
Emails:
Business:
valva@cop.ufl.edu