Jeffrey S Thinschmidt

Jeffrey S Thinschmidt,

Senior Biological Scientist

Department: Pharmacodynamics
Business Phone: (352) 392-7303
Business Email: tschmidt@ufl.edu

Publications

2022
A rapid in vitro assay for evaluating the effects of acetylcholinesterase inhibitors and reactivators in the rat basolateral amygdala.
Frontiers in cellular neuroscience. 16 [DOI] 10.3389/fncel.2022.1066312. [PMID] 36479275.
2019
Oxytocin Receptors Are Expressed by Glutamatergic Prefrontal Cortical Neurons That Selectively Modulate Social Recognition.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(17):3249-3263 [DOI] 10.1523/JNEUROSCI.2944-18.2019. [PMID] 30804095.
2019
Subunit contribution to NMDA receptor hypofunction and redox sensitivity of hippocampal synaptic transmission during aging.
Aging. 11(14):5140-5157 [DOI] 10.18632/aging.102108. [PMID] 31339863.
2017
Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells.
Stem cells (Dayton, Ohio). 35(5):1303-1315 [DOI] 10.1002/stem.2613. [PMID] 28299842.
2017
Erratum to: CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes.
Journal of molecular medicine (Berlin, Germany). 95(5):565-566 [DOI] 10.1007/s00109-017-1530-8. [PMID] 28421250.
2017
Hematopoietic stem/progenitor involvement in retinal microvascular repair during diabetes: Implications for bone marrow rejuvenation.
Vision research. 139:211-220 [DOI] 10.1016/j.visres.2017.06.016. [PMID] 29042190.
2016
CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes.
Journal of molecular medicine (Berlin, Germany). 94(11):1255-1265 [DOI] 10.1007/s00109-016-1433-0. [PMID] 27344677.
2016
Depressed basal hypothalamic neuronal activity in type-1 diabetic mice is correlated with proinflammatory secretion of HMBG1.
Neuroscience letters. 615:21-7 [DOI] 10.1016/j.neulet.2016.01.014. [PMID] 26777426.
2015
Central neural activation following contact sensitivity peripheral immune challenge: evidence of brain-immune regulation through C fibres.
Immunology. 146(2):206-16 [DOI] 10.1111/imm.12479. [PMID] 25967648.
2015
Loss of survival factors and activation of inflammatory cascades in brain sympathetic centers in type 1 diabetic mice.
American journal of physiology. Endocrinology and metabolism. 308(8):E688-98 [DOI] 10.1152/ajpendo.00504.2014. [PMID] 25714673.
2014
Alpha 1-antitrypsin therapy mitigated ischemic stroke damage in rats.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 23(5):e355-63 [DOI] 10.1016/j.jstrokecerebrovasdis.2013.12.029. [PMID] 24582784.
2014
Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice.
Investigative ophthalmology & visual science. 55(1):492-501 [DOI] 10.1167/iovs.13-12413. [PMID] 24370827.
2013
CNS inflammation and bone marrow neuropathy in type 1 diabetes.
The American journal of pathology. 183(5):1608-20 [DOI] 10.1016/j.ajpath.2013.07.009. [PMID] 24160325.
2013
Effects of Cfh Genotype and Dietary Glycemic Index On Age-Related Macular Degeneration in Mice
The FASEB's Journal. 27
2013
Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model.
Diabetologia. 56(3):644-53 [DOI] 10.1007/s00125-012-2781-0. [PMID] 23192694.
2013
Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow.
Diabetes. 62(1):273-82 [DOI] 10.2337/db12-0172. [PMID] 23193187.
2012
Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension.
Hypertension (Dallas, Tex. : 1979). 60(5):1316-23 [DOI] 10.1161/HYPERTENSIONAHA.112.199547. [PMID] 23045460.
2012
Liver X receptor modulates diabetic retinopathy outcome in a mouse model of streptozotocin-induced diabetes.
Diabetes. 61(12):3270-9 [DOI] 10.2337/db11-1596. [PMID] 22891211.
2011
The protective effects of plasma gelsolin on stroke outcome in rats.
Experimental & translational stroke medicine. 3(1) [DOI] 10.1186/2040-7378-3-13. [PMID] 22047744.
2009
Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795.
Neuropharmacology. 56(4):821-30 [PMID] 19705574.
2009
Selective inhibition of acetylcholine-evoked responses of alpha7 neuronal nicotinic acetylcholine receptors by novel tris- and tetrakis-azaaromatic quaternary ammonium antagonists.
Molecular pharmacology. 76(3):652-66 [DOI] 10.1124/mol.109.056176. [PMID] 19556356.
2008
Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated alpha7 nicotinic receptor gene transfer.
Brain research. 1203:51-60 [DOI] 10.1016/j.brainres.2008.02.011. [PMID] 18321476.
2007
Aging effects on the limits and stability of long-term synaptic potentiation and depression in rat hippocampal area CA1.
Journal of neurophysiology. 98(2):594-601 [PMID] 17553951.
2007
alpha7 Nicotinic receptor gene delivery into mouse hippocampal neurons leads to functional receptor expression, improved spatial memory-related performance, and tau hyperphosphorylation.
Neuroscience. 145(1):314-22 [PMID] 17218065.
2007
Partial agonist and neuromodulatory activity of S 24795 for alpha7 nAChR responses of hippocampal interneurons.
Neuropharmacology. 53(1):134-44 [PMID] 17544457.
2005
Medial septal/diagonal band cells express multiple functional nicotinic receptor subtypes that are correlated with firing frequency.
Neuroscience letters. 389(3):163-8 [PMID] 16112453.
2005
Septal innervation regulates the function of alpha7 nicotinic receptors in CA1 hippocampal interneurons.
Experimental neurology. 195(2):342-52 [PMID] 16000197.
2005
The effects of subunit composition on the inhibition of nicotinic receptors by the amphipathic blocker 2,2,6,6-tetramethylpiperidin-4-yl heptanoate.
Molecular pharmacology. 67(6):1977-90 [PMID] 15761116.
2004
Taurine-induced long-lasting potentiation in the rat hippocampus shows a partial dissociation from total hippocampal taurine content and independence from activation of known taurine transporters.
Journal of neurochemistry. 89(5):1195-205 [PMID] 15147512.
2003
Chronic ethanol treatment reduces the magnitude of hippocampal LTD in the adult rat.
Synapse (New York, N.Y.). 48(4):189-97 [PMID] 12687638.
1999
The development and pharmacological characterization of calcium channel currents in cultured embryonic rat septal cells.
Brain research. Developmental brain research. 118(1-2):13-21 [PMID] 10611499.
1998
The correction of alpha7 nicotinic acetylcholine receptor concentration-response relationships in Xenopus oocytes.
Neuroscience letters. 256(3):163-6 [PMID] 9855365.
1997
Activation and inhibition of rat neuronal nicotinic receptors by ABT-418.
British journal of pharmacology. 120(3):429-38 [PMID] 9031746.
1997
Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice.
Journal of neural transmission (Vienna, Austria : 1996). 104(11-12):1177-93 [PMID] 9503264.
1996
Differentiation of ionic currents in CNS progenitor cells: dependence upon substrate attachment and epidermal growth factor.
Experimental neurology. 140(2):206-17 [PMID] 8690063.
1995
The supramammillary nucleus: is it necessary for the mediation of hippocampal theta rhythm?
Neuroscience. 67(2):301-12 [PMID] 7675171.
1994
Separation of hippocampal theta dipoles by partial coherence analysis in the rat.
Brain research. 660(2):341-5 [PMID] 7820704.

Grants

Jul 2023 ACTIVE
Hematopoietic cell mobilization from distinct bone marrow compartments following retinal injury
Role: Other
Funding: UNIV OF ALABAMA BIRMINGHAM via NATL INST OF HLTH NEI

Contact Details

Phones:
Business:
(352) 392-7303
Emails:
Business:
tschmidt@ufl.edu
Addresses:
Business Mailing:
PO Box 116250
GAINESVILLE FL 32611
Business Street:
ROOM R5141 ARB
GAINESVILLE FL 326100267