Marwa Tantawy, Ph.D.
Research Assistant Professor
Department:
Pharmacotherapy & Translational Research
Business Phone:
(352) 392-2477
Business Email:
mtantawy@ufl.edu
About Marwa Tantawy
Marwa Tantawy, Ph.D., is a Research Assistant Professor in the Department of Pharmacotherapy and Translational Research at the University of Florida (UF) College of Pharmacy . Dr. Tantawy received a Ph.D. in Molecular Biology in 2016 from the College of Science, Ain Shams University, Egypt. She also got a master’s degree in immunology in 2010 from the College of Science, Cairo University, Egypt. Before Joining the UF Faculty in 2023, she completed a three-year post-doctoral fellowship in cardiovascular pharmacogenomics at the UF Pharmacotherapy and Translational Research Department. Dr. Tantawy has expertise in molecular oncology and laboratory experiments, particularly genetic association studies, including genome-wide association analyses (GWAS), genotyping, miRNA sequencing, Next Generation Sequencing, methylation, and cell culture. Dr. Tantawy’s current research focuses on adverse drug events such as cardiotoxicity related to cancer treatment, with a particular emphasis on multi-omics (genomics, epigenomics, metabolomics, and proteomics) to identify early detection markers that help in treatment management and reveal the underlying mechanisms.
Teaching Profile
Courses Taught
2024
PHA6449 Pharmacogenomic and Genomic Data Analysis
Publications
Academic Articles
2024
Circulating microRNA Biomarkers of Thiazide Response in Hypertension
Journal of the American Heart Association.
13(4)
[DOI] 10.1161/jaha.123.032433.
2024
Differential Expression of Circulating miRNAs and Carfilzomib-Related Cardiovascular Adverse Events in Patients with Multiple Myeloma
International Journal of Molecular Sciences.
25(14)
[DOI] 10.3390/ijms25147795.
[PMID] 39063038.
2024
Metabolomic signatures of carfilzomib‐related cardiotoxicity in patients with multiple myeloma
Clinical and Translational Science.
17(5)
[DOI] 10.1111/cts.13828.
[PMID] 38783568.
2024
Pharmacogenetic determinants of tenofovir diphosphate and lamivudine triphosphate concentrations in people with HIV/HBV coinfection.
Antimicrobial agents and chemotherapy.
68(9)
[DOI] 10.1128/aac.00549-24.
[PMID] 39078131.
2024
Research summary of poster presentations at the 2023 Florida cardio-oncology symposium.
American heart journal plus : cardiology research and practice.
37
[DOI] 10.1016/j.ahjo.2023.100348.
[PMID] 38510509.
2023
Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma.
Frontiers in cardiovascular medicine.
10
[DOI] 10.3389/fcvm.2023.1181806.
[PMID] 37408649.
2022
Clinical Significance of MicroRNA-29a and MicroRNA-100 Gene Expression in Pediatric Acute Myeloid Leukemia.
Journal of pediatric hematology/oncology.
44(2):e391-e395
[DOI] 10.1097/MPH.0000000000002168.
[PMID] 33902066.
2022
Genome-wide microRNA profiles identify miR-107 as a top miRNA associating with expression of the CYP3As and other drug metabolizing cytochrome P450 enzymes in the liver.
Frontiers in pharmacology.
13
[DOI] 10.3389/fphar.2022.943538.
[PMID] 36059981.
2021
Epigenetic Changes Associated With Anthracycline-Induced Cardiotoxicity.
Clinical and translational science.
14(1):36-46
[DOI] 10.1111/cts.12857.
[PMID] 32770710.
2021
Lactate Dehydrogenase B and Pyruvate Oxidation Pathway Associated With Carfilzomib-Related Cardiotoxicity in Multiple Myeloma Patients: Result of a Multi-Omics Integrative Analysis.
Frontiers in cardiovascular medicine.
8
[DOI] 10.3389/fcvm.2021.645122.
[PMID] 33996940.
2020
Genotypic characterization of multiple drug resistant Escherichia coli isolates from a pediatric cancer hospital in Egypt.
Scientific reports.
10(1)
[DOI] 10.1038/s41598-020-61159-z.
[PMID] 32139767.
2019
Novel CYP1B1 mutations and a possible prognostic use for surgical management of congenital glaucoma.
International journal of ophthalmology.
12(4):607-614
[DOI] 10.18240/ijo.2019.04.14.
[PMID] 31024815.
2018
Identification of microRNA signature in different pediatric brain tumors.
Genetics and molecular biology.
41(1):27-34
[DOI] 10.1590/1678-4685-GMB-2016-0334.
2016
The Liver MicroRNA Expression Profiles Associated With Chronic Hepatitis C Virus (HCV) Genotype-4 Infection: A Preliminary Study.
Hepatitis monthly.
16(4)
[DOI] 10.5812/hepatmon.33881.
[PMID] 27275163.
2015
Investigating the pretreatment miRNA expression patterns of advanced hepatocellular carcinoma patients in association with response to TACE treatment.
BioMed research international.
2015
[DOI] 10.1155/2015/649750.
[PMID] 25811030.
2013
Human cytomegalovirus infection enhances NF-κB/p65 signaling in inflammatory breast cancer patients.
PloS one.
8(2)
[DOI] 10.1371/journal.pone.0055755.
[PMID] 23418456.
2011
Mutational hotspots in the mitochondrial D-loop region of cancerous and precancerous colorectal lesions in Egyptian patients.
DNA and cell biology.
30(11):899-906
[DOI] 10.1089/dna.2010.1186.
[PMID] 21612400.
Grants
Jul 2024
ACTIVE
Cardiovascular Adverse Events Related to Aromatase Inhibitors in Breast Cancer
Role: Principal Investigator
Funding: FL BREAST CANCER FOU
Mar 2024
– Aug 2024
Cardiovascular Adverse Events Related to Aromatase Inhibitors in Female Breast Cancer
Role: Principal Investigator
Funding: ARIZONA STATE UNIVERSITY
via NATL INST OF HLTH
Jun 2022
ACTIVE
Genetic Associations of Ischemic Heart Disease and Symptoms Among Diverse Postmenopausal Women
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Education
Ph.D.
2016
·
Ain Shams University
M.S.
2010
·
Cairo University
Contact Details
Phones:
- Business:
- (352) 392-2477
Emails:
- Business:
- mtantawy@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100486
GAINESVILLE FL 32610 - Business Street:
-
1225 CENTER DR
GAINESVILLE FL 32610