Stephan Schmidt

Stephan Schmidt, Ph.D., F.C.P.

Associate Professor

Department: Pharmaceutics
Business Phone: (407) 313-7012
Business Email:

About Stephan Schmidt

Dr. Schmidt is an Associate Professor in the Department of Pharmaceutics and Director of the Center for Pharmacometrics and Systems Pharmacology in Lake Nona (Orlando). He received his B.S. in Pharmaceutical Sciences from the Friedrich-Alexander University in Erlangen, Germany in 2003 and his license to practice as a pharmacist in Germany in 2005. Dr. Schmidt received his Ph.D. from the University of Florida under the supervision of Dr. Hartmut Derendorf in 2008, before completing a 3 year postdoctoral fellowship under the supervision of Prof. Meindert Danhof in the Division of Pharmacology at the Leiden/Amsterdam Center for Drug Research in The Netherlands. During his postdoctoral fellowship, Dr. Schmidt was also a member of the Dutch Top Institute Pharma PK-PD modeling platform.

Dr. Schmidt received the Paul Ehrlich Society for Chemotherapy Thesis Award in 2010, the University of Florida Clinical Translational Science Institute Junior Faculty Pilot Program Award in 2012, the University of Florida Excellence Award for Assistant Professors in 2013, the Tanabe Young Investigator Award from the American College of Clinical Pharmacology (ACCP) in 2016 and was named International Educator of the Year of the College of Pharmacy at the University of Florida in 2014. He serves as the Chair of the Special Interest Group on PK/PD and Systems Pharmacology of the International Pharmaceutical Federation (FIP) and Chair of the Systems Pharmacology Community for the American Society for Clinical Pharmacology and Therapeutics (ASCPT). Dr. Schmidt is a Section Editor for the European Journal of Pharmaceutical Sciences and Editorial Board Member for the Journal of Clinical Pharmacology and ASCPT’s Pharmacometrics and Systems Pharmacology journal.


2009 The Journal of Clinical Pharmacology
2008 The Journal of Clinical Pharmacology


Aug 2019 ACTIVE
Pharmacometrics Modeling and Simulation of Probe Drugs Profiles Subjected to Competitive Enzyme Inhibition under Various Drug Administration Conditions
TABULA RASA HEALTHCARE · Principal Investigator
Jul 2019 – Jul 2019
Clinical Pharmacokinetics/Dynamics Fellowship 2019-2020 – Mohammad Akbar
GLAXO SMITHKLINE · Principal Investigator
Jul 2019 ACTIVE
Microdialysis study of Lipo680 in the animal model
GLAXO SMITHKLINE · Principal Investigator
Nov 2018 ACTIVE
Development of a Mechanism-Based Drug Disease Trial Model for Parkinsons disease (PD)
Aug 2018 ACTIVE
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Jul 2018 – Jun 2019
Microdialysis study of Lipo680 in the animal model
GLAXO SMITHKLINE · Principal Investigator
Jul 2018 ACTIVE
Development and qualification of an expanded Diabetes model
ELI LILLY AND CO · Principal Investigator
Jul 2018 – Jun 2019
Clinical Pharmacokinetics/Dynamics Fellowship 2018-2019
GLAXO SMITHKLINE · Principal Investigator
Jul 2018 – Apr 2019
Clinical Pharmacokinetics/Dynamics Fellowship 2018-2019 – Mohammad Akbar
GLAXO SMITHKLINE · Principal Investigator
Nov 2017 ACTIVE
Application of physiologically-based pharmacokinetic models to inform dosing recommendations for hormonal contraceptives co-administered with other medications
GATES FOU, BILL & MELINDA · Principal Investigator
Jan 2017 – Jan 2019
Improved pediatric dose selection through physiologically based pharmacokinetic modeling
F Hoffmann La Roche LTD · Principal Investigator
Aug 2016 ACTIVE
Optimizing combination therapy for accelerate clinical cure of tuberculosis
Jul 2016 – Dec 2018
Clinical Pharmacokinetic/Dynamics Fellowship
GLAXO SMITHKLINE · Principal Investigator
Nov 2015 – Aug 2017
Research Fellowship Program for Pharmacokinetics
GLAXO SMITHKLINE · Principal Investigator
Oct 2015 – Oct 2018
Translational Research Institute for Metabolism and Diab
Aug 2015 – Aug 2016
Pediatric PBPK model for large molecules in PK-Sim
BAYER TECHNOLOGY SERVICES · Principal Investigator
Apr 2015 – Feb 2017
In Silico Clinical Trial Qualification of Successful Bio
Apr 2015 – Oct 2017
Systems Pharmacology Based Modeling as a Platform for
ASTRAZENECA · Principal Investigator
Sep 2014 – Feb 2019
Pharmacokinetic and Pharmacodynamic (PK-PD) Studies of Cardiovascular Drugs
US FOOD AND DRUG ADMN · Project Manager
Sep 2014 – Aug 2018
A Model- and Systems-based Approach to Efficacy and Safety Questions Related to Generic Substitution
US FOOD AND DRUG ADMN · Principal Investigator
Apr 2013 – Dec 2016
In Silico Modeling of Biomarkers and Surrogate Endpoints
ELI LILLY AND CO · Principal Investigator
Jul 2007 – Aug 2016
Clinical and Translational Science Institute
UF RESEARCH FOU · Project Manager


2008 · University of Florida
2004 · Friedrich-Alexander University

Contact Details

(407) 313-7012