Stephan Schmidt

Stephan Schmidt, Ph.D., F.C.P.

Associate Professor; Certara Endowed Professor; Director Of The Center For Pharmacometrics And Systems Pharmacology

Department: Pharmaceutics
Business Phone: (407) 313-7012
Business Email: sschmidt@cop.ufl.edu

About Stephan Schmidt

Dr. Schmidt is an endowed Associate Professor in the Department of Pharmaceutics and Director of the Center for Pharmacometrics and Systems Pharmacology. He received his B.S. in Pharmaceutical Sciences from the Friedrich-Alexander University in Erlangen, Germany in 2003 and his license to practice as a pharmacist in Germany in 2005. Dr. Schmidt received his Ph.D. from the University of Florida under the supervision of Dr. Hartmut Derendorf in 2008, before completing a 3 year postdoctoral fellowship under the supervision of Profs. Meindert Danhof and Oscar Della Pasqua in the Division of Pharmacology at the Leiden/Amsterdam Center for Drug Research in The Netherlands. During his postdoctoral fellowship, Dr. Schmidt was also a member of the Dutch Top Institute Pharma PK-PD modeling platform.

Dr. Schmidt received the Paul Ehrlich Society for Chemotherapy Thesis Award in 2010, the University of Florida Clinical Translational Science Institute Junior Faculty Pilot Program Award in 2012, the University of Florida Excellence Award for Assistant Professors in 2013, the Tanabe Young Investigator Award from the American College of Clinical Pharmacology in 2016, and the Doctoral Thesis Mentoring Award from the College of Pharmacy at the University of Florida in 2018. He was also named International Educator of the Year of the College of Pharmacy at the University of Florida in 2014 and Fellow of the American College of Clinical Pharmacology in 2017. Dr. Schmidt is a Subject Editor for the European Journal of Pharmaceutical Sciences, Editorial Board Member for the Journal of Clinical Pharmacology, and serves on the Board of Regents for the American College of Clinical Pharmacology.

Research Profile

Dr. Schmidt’s research focuses on the development and application of disease-drug-trial models in the area of chronic progressive diseases, special patient populations, and drug-drug interactions. He published more than 100 peer-reviewed scientific manuscripts, 7 book chapters, and 2 textbooks, including the fifth edition of Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics textbook.

Publications

2020 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
2020 CPT: pharmacometrics & systems pharmacology
2020 Antimicrobial agents and chemotherapy
2019 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
2019 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
2019 Clinical Pharmacology & Therapeutics
2018 Antimicrobial Agents and Chemotherapy
2018 European Journal of Pharmaceutical Sciences
2017 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
2013 Journal of pharmaceutical sciences
2013 Clinical Pharmacology & Therapeutics
2011 Journal of Pharmacokinetics and Pharmacodynamics
2008 Journal of clinical pharmacology

Grants

Sep 2021 ACTIVE
CLINICAL PHARMACOKINETICS/DYNAMICS FELLOWSHIP PROGRAM FUNDING AGREEMENT YEAR 2
GLAXO SMITHKLINE · Principal Investigator
Sep 2020 ACTIVE
CLINICAL PHARMACOKINETICS/DYNAMICS FELLOWSHIP – YEAR 1
GLAXO SMITHKLINE · Principal Investigator
Jul 2020 ACTIVE
GSK Postdoctoral Fellowship
GLAXO SMITHKLINE · Principal Investigator
Jun 2020 ACTIVE
Development of a Physiologically based Pharmacokinetic Model (PBPK) to Inform the Development of a New Nasal Formulation of Epinephrine
ARS PHARMACEUTICALS ·
Aug 2019 – Aug 2020
Pharmacometrics Modeling and Simulation of Probe Drugs Profiles Subjected to Competitive Enzyme Inhibition under Various Drug Administration Conditions
TABULA RASA HEALTHCARE · Principal Investigator
Jul 2019 – Jun 2020
Microdialysis study of Lipo680 in the animal model
GLAXO SMITHKLINE · Principal Investigator
Jul 2019 – Jul 2019
Clinical Pharmacokinetics/Dynamics Fellowship 2019-2020 – Mohammad Akbar
GLAXO SMITHKLINE · Principal Investigator
Nov 2018 ACTIVE
Development of a Mechanism-Based Drug Disease Trial Model for Parkinsons disease (PD)
MILLENNIUM PHARMACEUTICAL ·
Aug 2018 ACTIVE
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
NATL INST OF HLTH NICHD ·
Jul 2018 – Jun 2019
Microdialysis study of Lipo680 in the animal model
GLAXO SMITHKLINE · Principal Investigator
Jul 2018 – Jul 2020
Development and qualification of an expanded Diabetes model
ELI LILLY AND CO · Principal Investigator
Jul 2018 – Jun 2019
Clinical Pharmacokinetics/Dynamics Fellowship 2018-2019
GLAXO SMITHKLINE · Principal Investigator
Jul 2018 – Apr 2019
Clinical Pharmacokinetics/Dynamics Fellowship 2018-2019 – Mohammad Akbar
GLAXO SMITHKLINE · Principal Investigator
Nov 2017 ACTIVE
Application of physiologically-based pharmacokinetic models to inform dosing recommendations for hormonal contraceptives co-administered with other medications
GATES FOU, BILL & MELINDA · Principal Investigator
Jan 2017 – Jan 2019
Improved pediatric dose selection through physiologically based pharmacokinetic modeling
F Hoffmann La Roche LTD · Principal Investigator
Aug 2016 ACTIVE
Optimizing combination therapy for accelerate clinical cure of tuberculosis
NATL INST OF HLTH NIAID ·
Jul 2016 – Dec 2018
Clinical Pharmacokinetic/Dynamics Fellowship
GLAXO SMITHKLINE · Principal Investigator
Nov 2015 – Aug 2017
Research Fellowship Program for Pharmacokinetics
GLAXO SMITHKLINE · Principal Investigator
Oct 2015 – Oct 2018
Translational Research Institute for Metabolism and Diab
TRANSLATIONAL RES INST METABOLISM & DIAB · Principal Investigator
Aug 2015 – Aug 2016
Pediatric PBPK model for large molecules in PK-Sim
BAYER TECHNOLOGY SERVICES · Principal Investigator
Apr 2015 – Feb 2017
In Silico Clinical Trial Qualification of Successful Bio
JANSSEN RESEARCH AND DEVELOPMENT · Principal Investigator
Apr 2015 – Oct 2017
Systems Pharmacology Based Modeling as a Platform for
ASTRAZENECA · Principal Investigator
Sep 2014 – Feb 2019
Pharmacokinetic and Pharmacodynamic (PK-PD) Studies of Cardiovascular Drugs
US FOOD AND DRUG ADMN · Project Manager
Sep 2014 – Aug 2018
A Model- and Systems-based Approach to Efficacy and Safety Questions Related to Generic Substitution
US FOOD AND DRUG ADMN · Principal Investigator
Apr 2013 – Dec 2016
In Silico Modeling of Biomarkers and Surrogate Endpoints
ELI LILLY AND CO · Principal Investigator
Jul 2007 – Aug 2016
Clinical and Translational Science Institute
UF RESEARCH FOU · Project Manager

Education

Ph.D.
2008 · University of Florida
B.S.
2004 · Friedrich-Alexander University

Contact Details

Phones:
Business:
(407) 313-7012
Emails: