Sushobhan Mukhopadhyay

Sushobhan Mukhopadhyay, Ph.D.

Assistant Scientist

Department: Medicinal Chemistry
Business Phone: (352) 284-9649
Business Email:

About Sushobhan Mukhopadhyay

Sushobhan Mukhopadhyay, Ph.D., was appointed as an assistant scientist in the College of Pharmacy, Department of Medicinal Chemistry in July 2022. Sushobhan received his Bachelor of Science (Chemistry) and Master of Science (Organic Chemistry) degrees from University of Kalyani, India. He pursued his Ph.D. in Medicinal Chemistry from CSIR-Central Drug Research Institute, India in 2020. His doctoral work focused on the synthesis of new heterocycles, development of innovative synthetic methodologies, synthesis and biological evaluation of small molecules for anti-proliferative and anti-infective agent. Upon completion of his doctoral studies, Sushobhan joined the University of Florida, College of Pharmacy in December 2020 as a Postdoctoral Associate in the Department of Medicinal Chemistry working in Dr. Christopher McCurdy’s laboratory. Sushobhan has keen interest in the development of novel molecules for the treatment of pain and opioid use disorder.


Early Career Achievement Award in Chemical Science
2020 · CSIR-Central Drug Research Institute, India
Senior Research Fellow Award
2016 · Council of Scientific & Industrial Research, India
Best Publication award in Chemical Science
2015 · CSIR-Central Drug Research Institute, India
Junior Research Fellowship
2014 · Council of Scientific and Industrial Research, India

Research Profile

Areas of Interest
  • Substance Use Epidemiology, particularly opioids
  • Drug development
  • Medicinal chemistry
  • Natural products
  • Organic Chemistry


Effects of kratom on driving: Results from a cross-sectional survey, ecological momentary assessment, and pilot simulated driving Study.
Traffic injury prevention. 25(4):594-603 [DOI] 10.1080/15389588.2024.2327827. [PMID] 38497810.
Formation of multiple ion types during MALDI imaging mass spectrometry analysis of Mitragyna speciosa alkaloids in dosed rat brain tissue.
Talanta. 274 [DOI] 10.1016/j.talanta.2024.125923. [PMID] 38569366.
Pharmacokinetic Interaction of Kratom and Cannabidiol in Male Rats.
Pharmaceutics. 16(3) [DOI] 10.3390/pharmaceutics16030318. [PMID] 38543213.
Responses to a “Typical” Morning Dose of Kratom in People Who Use Kratom Regularly: A Direct-Observation Study.
Journal of addiction medicine. 18(2):144-152 [DOI] 10.1097/ADM.0000000000001259. [PMID] 38174871.
An in vitro evaluation of kratom (Mitragyna speciosa) on the catalytic activity of carboxylesterase 1 (CES1).
Chemico-biological interactions. 384 [DOI] 10.1016/j.cbi.2023.110715. [PMID] 37716419.
Cannabidiol and mitragynine exhibit differential interactive effects in the attenuation of paclitaxel-induced mechanical allodynia, acute antinociception, and schedule-controlled responding in mice
Pharmacological Reports. 75(4):937-950 [DOI] 10.1007/s43440-023-00498-w. [PMID] 37243887.
Characterization of a Mouse Model of Neuropathic Pain Induced by Calcaneus Implantation of NCTC 2472 Mouse Sarcoma Cells
ASPET 2023 Annual Meeting Abstract – Cancer Pharmacology. [DOI] 10.1124/jpet.122.243040.
Metabolite and Molecular Characterization of Mitragyna speciosa Identifies Developmental and Genotypic Effects on Monoterpene Indole and Oxindole Alkaloid Composition.
Journal of natural products. 86(4):1042-1052 [DOI] 10.1021/acs.jnatprod.3c00092. [PMID] 36913648.
Mitragynine Pretreatment Prevents Morphine-Induced Respiratory Depression
ASPET 2023 Annual Meeting Abstract – Toxicology. [DOI] 10.1124/jpet.122.261220.
Receptor Selectivity and Therapeutic Potential of Kratom in Substance Use Disorders
Current Addiction Reports. [DOI] 10.1007/s40429-023-00472-9.
Effects of Mitragynine and its Active Metabolites on the Reinforcing Effects of Remifentanil and Cocaine in Rats Self‐Administering Remifentanil
The FASEB Journal. 36(S1) [DOI] 10.1096/fasebj.2022.36.s1.r5776.
Antileishmanial assessment of isoxazole derivatives against L. donovani
RSC Medicinal Chemistry. 11(9):1053-1062 [DOI] 10.1039/d0md00083c. [PMID] 33479698.
Applications of Sodium Nitrite in Organic Synthesis
European Journal of Organic Chemistry. 2019(38):6424-6451 [DOI] 10.1002/ejoc.201900951.
NaNO2/I2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides
Tetrahedron Letters. 60(3):248-251 [DOI] 10.1016/j.tetlet.2018.12.025.
Direct Transformation of Arylamines to Aryl Halides via Sodium Nitrite and N -Halosuccinimide
Chemistry – A European Journal. 24(55):14622-14626 [DOI] 10.1002/chem.201803347. [PMID] 30040166.
TBHP as Methyl Source under Metal-Free Aerobic Conditions To Synthesize Quinazolin-4(3H )-ones and Quinazolines by Oxidative Amination of C(sp3 )-H Bond
European Journal of Organic Chemistry. 2018(22):2784-2794 [DOI] 10.1002/ejoc.201800495.
Efficient Transformation of Alkyl 3-nitro-5-(aryl/alkyl)isoxazole-4-carboxylates into 3-amino- and 3-hydrazinyl-5-aryl/alkyl-isoxazole-4-carboxylates in Aqueous Solution
Advanced Synthesis & Catalysis. 359(22):4050-4056 [DOI] 10.1002/adsc.201700881.
Corrigendum: Synthesis of 3,4,5-Trisubstituted Isoxazoles from Morita-Baylis-Hillman Acetates by an NaNO2/I2-Mediated Domino Reaction.
Angewandte Chemie (International ed. in English). 55(4) [DOI] 10.1002/anie.201511039. [PMID] 26779865.
Metal-Free Oxidative Nitration of α-Carbon of Carbonyls Leads to One-Pot Synthesis of Thiohydroximic Acids from Acetophenones
Organic Letters. 18(17):4190-4193 [DOI] 10.1021/acs.orglett.6b01807. [PMID] 27541178.
NaNO2/I2-Mediated Regioselective Synthesis of Nitrosoimidazoheterocycles from Acetophenones by a Domino Process
European Journal of Organic Chemistry. 2016(22):3836-3844 [DOI] 10.1002/ejoc.201600553.
Synthesis of 3,4,5-Trisubstituted Isoxazoles from Morita-Baylis-Hillman Acetates by an NaNO2 /I2 -Mediated Domino Reaction.
Angewandte Chemie (International ed. in English). 54(37):10926-30 [DOI] 10.1002/anie.201504529. [PMID] 26215456.
Synthesis of 3,4,5-Trisubstituted Isoxazoles from Morita-Baylis-Hillman Acetates by an NaNO2/I2-Mediated Domino Reaction
Angewandte Chemie. 127(37):11076-11080 [DOI] 10.1002/ange.201504529.
Room-Temperature Chemoselective Reduction of Nitro Groups Using Non-noble Metal Nanocatalysts in Water
Inorganic Chemistry. 53(6):2904-2909 [DOI] 10.1021/ic402674z.


2020 · CSIR-Central Drug Research Institute, India
Master of Science in Chemistry
2011 · University of Kalyani, India
Bachelor of Science in Chemistry
2009 · University of Kalyani, India

Contact Details

(352) 284-9649
Business Mailing:
PO Box 100485