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UF Health University of Florida
College of Pharmacy UNIVERSITY of FLORIDA
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Xingui Liu

Xingui Liu, Ph.D.

Assistant Professor

Department: Medicinal Chemistry
Business Phone: (352) 294-5791
Business Email: xliu3@ufl.edu
CV: View Curriculum Vitae

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About Xingui Liu

Xingui Liu joined the Department of Medicinal Chemistry at the College of Pharmacy, University of Florida as an Assistant Professor in 2023. Her research interest focuses on proximity agents-based early drug discovery, including hit identification, lead optimization, and assay development. Before starting her independent research career, Dr. Liu was a Marie Skłodowska-Curie fellow in Prof. Alessio Ciulli’s lab at the Center for Targeted Protein Degradation (CeTPD), University of Dundee where she developed PROTAC degraders of Leucine Rich Repeat Kinase 2 (LRRK2), a promising target for Parkinson’s disease. Prior to this, Xingui was a Postdoc associate at the University of Florida working with Prof. Guangrong Zheng and Prof. Daohong Zhou. She earned her PhD degree in Guangrong Zheng’s lab at the University of Arkansans for Medical Sciences, where she designed, synthesized, and characterized delta-tocotrienol based radio-protectors.

Related Links:
Lab Website

Teaching Profile

Courses Taught

  1. PHA6467C – Drug Design II

    College of Pharmacy

  2. PHA6934 – Seminar in Medicinal Chemistry

    College of Pharmacy

  3. PHA6938 – Research Seminar

    College of Pharmacy

  4. PHA5782C – Patient Care 2: Introduction to Infectious Disease and Oncology

    College of Pharmacy

  5. PHA5878C – Pt Care 3: Cv and Pulm

    College of Pharmacy

  6. PHA7979 – Advanced Research

    College of Pharmacy

  7. PHA6935 – Selected Topics in Pharmacy

    College of Pharmacy

  8. PHA6910 – Supervised Research

    College of Pharmacy

  9. PHA6447 – Drug Design

    College of Pharmacy

Research Profile

Research in her laboratory is at the interface of chemistry and biology, focusing on discovering and developing small molecules that target E3 ligases, promote protein protein interactions, or induce protein degradation.

Areas of Interest

  • Medicinal chemistry
  • Small molecule drug discovery
  • Targeted protein degradation

Publications

Academic Articles

Grants

  1. Exploiting LK81 Inactivation for Enhanced Treatment Efficacy and Immune Response in Lung Cancer

    Active

    Role:
    Co-Investigator
    Funding:
    FL DEPT OF HLTH BANKHEAD-COLEY CANCER RE

Contact Details

Phones:
Business:
(352) 294-5791
Emails:
Business:
xliu3@ufl.edu
Addresses:
Business Mailing:
PO Box 100485
 GAINESVILLE FL 32610
Business Street:
1345 CENTER DR
 GAINESVILLE FL 32610