Lawrence Lesko

Lawrence Lesko Ph.D.

Professor Emeritus

Department: Pharmaceutics
Business Email: llesko@cop.ufl.edu

About Lawrence Lesko

Lawrence J. Lesko, Ph.D., F.C.P. joined the UF Research and Academic Center in Lake Nona (Orlando) in July 2011.

Before joining UF, Dr. Lesko worked nearly 20 years in the Food and Drug Administration’s Center for Drug Evaluation and Research as the Director of the Office of Clinical Pharmacology. He was also Chair of the Clinical Pharmacology Coordinating Subcommittee of the FDA’s Medical Policy Coordinating Committee and authored or co-authored numerous Guidance for Industry, and started the FDA’s Voluntary Genomics Data Submission Program and Mechanistic Drug Safety Program.

Lesko has published more than 200 peer-reviewed scientific publications and is a frequent invited national and international speaker in clinical pharmacology, personalized medicine, pharmacometrics and systems pharmacology. His research interests include drug development and regulatory science, quantitative clinical pharmacology and pharmacogenomics.

In 2011, Lesko received the Gary Neil Prize for Innovation in Drug Development from the American Society of Clinical Pharmacology and Therapeutics (ASCPT). He also received the Coriell Scientific Leadership Award for Personalized Medicine (2010), the Rawls-Palmer Progress in Medicine award from ASCPT (2007), the University of North Carolina Institute for Pharmacogenomics and Individualized Therapy Award for Clinical Service (2007), and the Nathanial B. Kwit Distinguished Service Award for Clinical Pharmacology from the American College of Clinical Pharmacology (2007). Lesko served as President of the American College of Clinical Pharmacology in 2004-2006. He is a Fellow in the Japanese Society for the Study of Xenobiotics, American College of Clinical Pharmacology and the American Association of Pharmaceutical Scientists. He is Board Certified in Clinical Pharmacology and a registered pharmacist.

Publications

2013 Clinical Pharmacology & Therapeutics
2012 Clinical Pharmacology & Therapeutics
2012 Clinical Pharmacology & Therapeutics
2012 Clinical Pharmacology & Therapeutics

Grants

October 2015 – October 2018
Translational Research Institute for Metabolism and Diab
TRANSLATIONAL RES INST METABOLISM & DIAB · Project Manager
April 2015 – August 2017
Pharmacogenomics of Oxydocone in Chronic Pain Management
RAJ ENTERPRISES OF CENTRAL FLORIDA LLC · Principal Investigator
September 2014 – August 2018
A Model- and Systems-based Approach to Efficacy and Safety Questions Related to Generic Substitution
US FOOD AND DRUG ADMN · Project Manager
June 2014 – April 2016
Vertex – Cystic Fibrosis Research
VERTEX PHARMACEUTICALS · Principal Investigator
March 2014 – March 2016
Application of Population Pharmacokinetic/Pharmacodynami
TAKEDA PHARMACEUTICALS INTERNATIONAL · Principal Investigator
April 2013 – April 2016
Educational Grant Agreement
DAIICHI PHARMACEUTICAL PHARM CORP · Principal Investigator

Education

1971
Ph.D.
Temple University Health Science Center
1967
B.S.
Temple University Health Science Center

Contact Details

Emails:
Business:
llesko@cop.ufl.edu
Addresses:
Mailing:
6550 SANGER ROAD, OFFICE 464
ORLANDO, FL 328277400
Physical:
6550 SANGER ROAD, OFFICE 464
ORLANDO, FL 328277400