Tanvir Khaliq

Tanvir Khaliq, Ph.D.

Senior Chemist

Department: Medicinal Chemistry
Business Phone: (352) 273-6061
Business Email: tanvirkhaliq@cop.ufl.edu

Publications

2020
Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles.
Molecules (Basel, Switzerland). 25(17) [DOI] 10.3390/molecules25173999. [PMID] 32887303.
2016
Development of a robust, sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor antagonist [D-Trp]CJ-15,208 in plasma and application to an initial pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1028:11-15 [DOI] 10.1016/j.jchromb.2016.05.043. [PMID] 27318293.
2014
Synthesis, structure-activity relationships, and biological studies of chromenochalcones as potential antileishmanial agents.
Journal of medicinal chemistry. 57(8):3342-57 [DOI] 10.1021/jm401893j. [PMID] 24635539.
2013
Anti-secretory and cyto-protective effects of peganine hydrochloride isolated from the seeds of Peganum harmala on gastric ulcers.
Phytomedicine : international journal of phytotherapy and phytopharmacology. 20(13):1180-5 [DOI] 10.1016/j.phymed.2013.06.017. [PMID] 23880327.
2013
Synthesis and insight into the structure-activity relationships of chalcones as antimalarial agents.
Journal of medicinal chemistry. 56(1):31-45 [DOI] 10.1021/jm300588j. [PMID] 23270565.
2012
Anti-diabetic and anti-oxidative effects of 4-hydroxypipecolic acid in C57BL/KsJ-db/db mice.
Human & experimental toxicology. 31(1):57-65 [DOI] 10.1177/0960327111407227. [PMID] 21653626.
2011
Tandem mass spectrometry for the direct assay of lysosomal enzymes in dried blood spots: application to screening newborns for mucopolysaccharidosis IVA.
Clinical chemistry. 57(1):128-31 [DOI] 10.1373/clinchem.2010.149880. [PMID] 21030685.
2010
Design and synthesis of substrates for newborn screening of Maroteaux-Lamy and Morquio A syndromes.
Bioorganic & medicinal chemistry letters. 20(20):5994-6 [DOI] 10.1016/j.bmcl.2010.08.080. [PMID] 20833037.
2009
Peganine hydrochloride dihydrate an orally active antileishmanial agent.
Bioorganic & medicinal chemistry letters. 19(9):2585-6 [DOI] 10.1016/j.bmcl.2009.03.039. [PMID] 19339182.
2009
Synthesis of alpha-amyrin derivatives and their in vivo antihyperglycemic activity.
European journal of medicinal chemistry. 44(3):1215-22 [DOI] 10.1016/j.ejmech.2008.09.011. [PMID] 18947904.
2008
13C NMR spectroscopy of D and B, D-ring seco-limonoids of Meliaceae family.
Natural product research. 22(9):763-800 [DOI] 10.1080/14786410701628812. [PMID] 18569718.
2008
Antileishmanial activity mediated by apoptosis and structure-based target study of peganine hydrochloride dihydrate: an approach for rational drug design.
The Journal of antimicrobial chemotherapy. 62(5):998-1002 [DOI] 10.1093/jac/dkn319. [PMID] 18694906.
2007
Antidyslipidemic activity of Indigofera tinctoria.
Journal of herbal pharmacotherapy. 7(1):59-64 [PMID] 17594987.
View on: PubMed
2007
Antihyperglycemic and antidyslipidemic agent from Aegle marmelos.
Bioorganic & medicinal chemistry letters. 17(6):1808-11 [PMID] 17197179.
View on: PubMed
2006
4-hydroxyisoleucine an unusual amino acid as antidyslipidemic and antihyperglycemic agent.
Bioorganic & medicinal chemistry letters. 16(2):293-6 [PMID] 16246556.
View on: PubMed
2006
Antidyslipidemic activity of furano-flavonoids isolated from Indigofera tinctoria.
Bioorganic & medicinal chemistry letters. 16(13):3411-4 [PMID] 16644212.
View on: PubMed
2006
Xyloccensin X and Y, two new limonoids from xylocarpus molluccensis: NMR investigation in mixture.
Magnetic resonance in chemistry : MRC. 44(11):1054-7 [PMID] 16909437.
View on: PubMed
2005
Synthesis of chromenochalcones and evaluation of their in vitro antileishmanial activity.
Bioorganic & medicinal chemistry. 13(23):6543-50 [PMID] 16185885.
View on: PubMed

Teaching Profile

Courses Taught
2016
PHA5438 Medicinal Chemistry 2

Contact Details

Phones:
Business:
(352) 273-6061
Emails: