Julie A Johnson, Pharm.D.
Distinguished Professor
About Julie A Johnson
Julie A. Johnson, Pharm.D., is a distinguished professor of Pharmacy and Medicine at the University of Florida. She previously served as dean of the UF College of Pharmacy from 2013 until 2022. She received her B.S. in Pharmacy from the Ohio State University and her Pharm.D. from the University of Texas at Austin and the UT Health Science Center at San Antonio. She completed a post-doctoral fellowship in cardiovascular pharmacology/pharmacokinetics at Ohio State.
Johnson’s research focuses on cardiovascular pharmacogenomics and genomic medicine implementation. She is an internationally-recognized leader in pharmacogenomics and genomic medicine, with over 300 peer reviewed publications and nearly $50 million in research funding as principal investigator. In 2015, 2016, 2017 she was named a Thomson Reuters (now Clarivate Analytics) Highly Cited Scientist in Pharmacology and Toxicology, and in 2018 in the Cross Discipline category, indicating she is in the top 1% of the most highly cited scientists in the field globally.
Johnson has served on the Nonprescription Drugs Advisory Committee of the FDA, the XNDA Study Section at NIH, and in numerous scientific capacities with NIH’s NHLBI. She has had leadership roles in the American College of Clinical Pharmacy (ACCP), the American Heart Association (AHA), and the American Society of Clinical Pharmacology and Therapeutics (ASCPT), for which she completed her term as President in 2017. She is an elected fellow of the ACCP, the AHA and the American College of Clinical Pharmacology (ACCP-Pharmacology). Johnson was elected to the National Academy of Medicine (formerly Institute of Medicine) in 2014 and has received numerous other awards including teaching awards from both the University of Tennessee (1996) and the University of Florida (2001); the Ohio State University Alumni Association William Oxley Thompson Award for early career achievement (1997), Leon I Goldberg Young Investigator Award from the ASCPT (2004), Paul Dawson Biotechnology Research Award, American Association of Colleges of Pharmacy (AACP) (2007), Therapeutic Frontiers Award (2009) and Russell R Miller Award for Contributions to the Literature (2010), both from ACCP, the Southeastern Universities Research Association Distinguished Scientist Award (2015); AACP Volwiler Research Achievement Award (2016), the ACCP-Pharmacology Distinguished Scientist Award (2019), the ACCP Paul Parker Medal (2019), elected fellow of the American Association for the Advancement of Science (2020), the Rawls Palmer Progress in Medicine Award from the American Society for Clinical Pharmacology and Therapeutics (2021), and the Precision Medicine World Conference Luminary Award recipient (2021), among others.
Teaching Profile
Courses Taught
2013-2021
PHA7979 Advanced Research
2020
PHA6910 Supervised Research
2013-2022
PHA7980 Research for Doctoral Dissertation
2014-2018,2021-2023
PHA6938 Research Seminar
2016
PHA6971 Research for Master’s Thesis
2015
GMS7794 Neuroscience Seminar
2009-2011,2013
PHA5907 Research in Phar Prac
2013
PHA5933 Select Top Pharmacy
2012-2013
PHA5787 Pharmacotherapy 5
2011-2012
PHA5782 Pharmacotherapy 2
2012
PHA5113 Personalized Medicine
2011-2012
PHA5784 Pharmacotherapy 4
2008,2010-2012,2012
PHA6449 Pharmacogenomics
2011
PHA5113C Thera Mon/Pharmacogen
2009-2010
PHA4907 Probs in Pharm Prac
2010
IDH4917 Undergrad Research
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0001-9847-1932
Publications
2022
A randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.
Clinical and translational science.
[DOI] 10.1111/cts.13294.
[PMID] 35488487.
2022
Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.
Frontiers in physiology.
[DOI] 10.3389/fphys.2022.909870.
[PMID] 35812313.
2022
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2526.
[PMID] 35034351.
2022
Comparison of Data Normalization Strategies for Array-Based MicroRNA Profiling Experiments and Identification and Validation of Circulating MicroRNAs as Endogenous Controls in Hypertension.
Frontiers in genetics.
[DOI] 10.3389/fgene.2022.836636.
[PMID] 35432462.
2022
CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings.
Journal of the American Heart Association.
[DOI] 10.1161/JAHA.121.024159.
[PMID] 35156424.
2022
Design and rationale of GUARDD-US: A pragmatic, randomized trial of genetic testing for APOL1 and pharmacogenomic predictors of antihypertensive efficacy in patients with hypertension.
Contemporary clinical trials.
[DOI] 10.1016/j.cct.2022.106813.
[PMID] 35660539.
2022
Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study.
Genes.
[DOI] 10.3390/genes13071260.
[PMID] 35886043.
2022
Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-Site, Real-World Investigation.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2612.
[PMID] 35429163.
2022
Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators.
Clinical and translational science.
[DOI] 10.1111/cts.13376.
[PMID] 35899435.
2022
Warfarin Dosing in Patients With CYP2C9*5 Variant Alleles.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2549.
[PMID] 35108398.
2022
β1-receptor polymorphisms and junctional ectopic tachycardia in children after cardiac surgery.
Clinical and translational science.
[DOI] 10.1111/cts.13178.
[PMID] 34713976.
2021
A hybrid implementation-effectiveness randomized trial of CYP2D6-guided postoperative pain management.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-020-01050-4.
[PMID] 33420349.
2021
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2355.
[PMID] 34231218.
2021
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2015.
[PMID] 32770672.
2021
Determining the potential clinical value of panel-based pharmacogenetic testing in patients with chronic pain or gastroesophageal reflux disease.
The pharmacogenomics journal.
[DOI] 10.1038/s41397-021-00244-6.
[PMID] 34075203.
2021
Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-021-01118-9.
[PMID] 33782552.
2021
Evaluating an interactive teaching approach with personal genotyping to provide pharmacy students with a knowledge base for clinical pharmacogenetics
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY.
[DOI] 10.1002/jac5.1335.
2021
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality.
European heart journal.
[DOI] 10.1093/eurheartj/ehab107.
[PMID] 33748830.
2021
How to Integrate CYP2D6 Phenoconversion Into Clinical Pharmacogenetics: A Tutorial.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2354.
[PMID] 34231197.
2021
Impact of the CYP2C19*17 Allele on Outcomes in Patients Receiving Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2039.
[PMID] 32897581.
2021
Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients.
Metabolites.
[DOI] 10.3390/metabo11090645.
[PMID] 34564461.
2021
Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-021-01269-9.
[PMID] 34282303.
2021
Race-Specific Comparisons of Antihypertensive and Metabolic Effects of Hydrochlorothiazide and Chlorthalidone.
The American journal of medicine.
[DOI] 10.1016/j.amjmed.2020.12.015.
[PMID] 33434556.
2021
Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network.
Journal of personalized medicine.
[DOI] 10.3390/jpm11070647.
[PMID] 34357114.
2021
Tribute to Professor Hartmut Derendorf – 1953 to 2020: Driving force in Clinical Pharmacology and Mentor Extraordinaire.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.2193.
[PMID] 33667324.
2020
A Scoping Review of the Evidence Behind Cytochrome P450 2D6 Isoenzyme Inhibitor Classifications.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1768.
[PMID] 31910286.
2020
Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data.
Circulation.
[DOI] 10.1161/CIRCULATIONAHA.119.045526.
[PMID] 32654539.
2020
Blending Traditional Vocational Services and Individualized Placement and Support for Formerly Incarcerated Veterans.
Psychiatric services (Washington, D.C.).
[DOI] 10.1176/appi.ps.201900421.
[PMID] 32393158.
2020
Clinical Pharmacology Education – The Decade Ahead.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1652.
[PMID] 31709518.
2020
Clinical Utility of Pharmacogene Panel-Based Testing in Patients Undergoing Percutaneous Coronary Intervention.
Clinical and translational science.
[DOI] 10.1111/cts.12729.
[PMID] 31758664.
2020
Combination Antihypertensive Therapy Prescribing and Blood Pressure Control in a Real-World Setting.
American journal of hypertension.
[DOI] 10.1093/ajh/hpz196.
[PMID] 31853537.
2020
Correction: Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-020-0931-1.
[PMID] 32747766.
2020
Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data.
The pharmacogenomics journal.
[DOI] 10.1038/s41397-020-0162-5.
[PMID] 32042096.
2020
Design and Early Implementation Successes and Challenges of a Pharmacogenetics Consult Clinic.
Journal of clinical medicine.
[DOI] 10.3390/jcm9072274.
[PMID] 32708920.
2020
Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-020-0894-2.
[PMID] 32678355.
2020
Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.
CPT: pharmacometrics & systems pharmacology.
[DOI] 10.1002/psp4.12563.
[PMID] 33067866.
2020
How to Transition from Single-Gene Pharmacogenetic Testing to Preemptive Panel-Based Testing: A Tutorial.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1912.
[PMID] 32460360.
2020
Pharmacogenetic factors affecting β-blocker metabolism and response
Expert Opinion on Drug Metabolism & Toxicology.
[DOI] 10.1080/17425255.2020.1803279.
[PMID] 32726152.
2020
Response to: Heterogeneous Treatment Response by Race Cannot Be Claimed in the Absence of Evidence.
American journal of hypertension.
[DOI] 10.1093/ajh/hpz168.
[PMID] 31891170.
2020
Sorting nexin 1 loss results in increased oxidative stress and hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[DOI] 10.1096/fj.201902448R.
[PMID] 32293069.
2020
The Patient-Centered Future of Clinical Pharmacology.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1681.
[PMID] 31751490.
2020
What will be your legacy in pharmacy? How will you be a Paul Parker?
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY.
[DOI] 10.1002/jac5.1195.
2019
A case for genotype-guided pain management.
Pharmacogenomics.
[DOI] 10.2217/pgs-2019-0068.
[PMID] 31368851.
2019
Antihypertensive therapy prescribing patterns and correlates of blood pressure control among hypertensive patients with chronic kidney disease.
Journal of clinical hypertension (Greenwich, Conn.).
[DOI] 10.1111/jch.13429.
[PMID] 30427124.
2019
Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.
Circulation. Genomic and precision medicine.
[DOI] 10.1161/CIRCGEN.119.002471.
[PMID] 30897348.
2019
Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene-drug pairs across ambulatory care settings.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-019-0500-7.
[PMID] 30926959.
2019
CYP2D6-guided opioid therapy improves pain control in CYP2D6 intermediate and poor metabolizers: a pragmatic clinical trial.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-018-0431-8.
[PMID] 30670877.
2019
Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1323.
[PMID] 30506689.
2019
Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[DOI] 10.1016/j.ejps.2019.02.013.
[PMID] 30753892.
2019
Essential Characteristics of Pharmacogenomics Study Publications.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1279.
[PMID] 30406943.
2019
Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals.
Hypertension (Dallas, Tex. : 1979).
[DOI] 10.1161/HYPERTENSIONAHA.118.12177.
[PMID] 31327267.
2019
Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response
Scientific Reports.
[DOI] 10.1038/s41598-019-53345-5.
[PMID] 31754133.
2019
Genome-wide association analysis of common genetic variants of resistant hypertension.
The pharmacogenomics journal.
[DOI] 10.1038/s41397-018-0049-x.
[PMID] 30237584.
2019
Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies).
Journal of the American Heart Association.
[DOI] 10.1161/JAHA.119.013115.
[PMID] 31423876.
2019
Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta-Blockers in European Americans.
Clinical and translational science.
[DOI] 10.1111/cts.12643.
[PMID] 31033190.
2019
Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers.
PloS one.
[DOI] 10.1371/journal.pone.0221957.
[PMID] 31532792.
2019
Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-019-0484-3.
[PMID] 30894703.
2019
Novel Implementation of Genotype-Guided Proton Pump Inhibitor Medication Therapy in Children: A Pilot, Randomized, Multisite Pragmatic Trial.
Clinical and translational science.
[DOI] 10.1111/cts.12589.
[PMID] 30341969.
2019
Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans With Uncomplicated Hypertension.
American journal of hypertension.
[DOI] 10.1093/ajh/hpz022.
[PMID] 30753254.
2019
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Nature genetics.
[DOI] 10.1038/s41588-019-0449-0.
[PMID] 31160810.
2019
Qualitative study of system-level factors related to genomic implementation.
Genetics in medicine : official journal of the American College of Medical Genetics.
[DOI] 10.1038/s41436-018-0378-9.
[PMID] 30467402.
2019
Subsequent Event Risk in Individuals With Established Coronary Heart Disease.
Circulation. Genomic and precision medicine.
[DOI] 10.1161/CIRCGEN.119.002470.
[PMID] 30896328.
2019
β2 -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies.
Journal of clinical pharmacology.
[DOI] 10.1002/jcph.1443.
[PMID] 31090079.
2018
Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.
BMC medical genomics.
[DOI] 10.1186/s12920-018-0370-x.
[PMID] 29925376.
2018
Clinical implementation of rapid CYP2C19 genotyping to guide antiplatelet therapy after percutaneous coronary intervention.
Journal of translational medicine.
[DOI] 10.1186/s12967-018-1469-8.
[PMID] 29642909.
2018
Generic Cost-Effectiveness Models: A Proof of Concept of a Tool for Informed Decision-Making for Public Health Precision Medicine.
Public health genomics.
[DOI] 10.1159/000500725.
[PMID] 31189173.
2018
Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses).
Circulation. Genomic and precision medicine.
[DOI] 10.1161/CIRCGEN.117.001854.
[PMID] 29650764.
2018
Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients.
Journal of the American Heart Association.
[DOI] 10.1161/JAHA.117.007339.
[PMID] 29523524.
2018
Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers.
Journal of the American Heart Association.
[DOI] 10.1161/JAHA.117.006463.
[PMID] 29478026.
2018
Implementation of Standardized Clinical Processes for TPMT Testing in a Diverse Multidisciplinary Population: Challenges and Lessons Learned.
Clinical and translational science.
[DOI] 10.1111/cts.12533.
[PMID] 29351371.
2018
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Nature genetics.
[DOI] 10.1038/s41588-018-0058-3.
[PMID] 29531354.
2018
Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.
JACC. Cardiovascular interventions.
[DOI] 10.1016/j.jcin.2017.07.022.
[PMID] 29102571.
2018
Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1006.
[PMID] 29280137.
2018
Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine.
Expert opinion on drug metabolism & toxicology.
[DOI] 10.1080/17425255.2018.1461835.
[PMID] 29620484.
2018
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.
Clinical pharmacology and therapeutics.
[DOI] 10.1002/cpt.1048.
[PMID] 29460415.
2018
Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide.
Pharmacogenetics and genomics.
[DOI] 10.1097/FPC.0000000000000353.
[PMID] 30289819.
2018
Whole Transcriptome Profiling: An RNA-Seq Primer and Implications for Pharmacogenomics Research.
Clinical and translational science.
[DOI] 10.1111/cts.12511.
[PMID] 28945944.
2017
Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension.
Journal of clinical hypertension (Greenwich, Conn.).
[DOI] 10.1111/jch.13094.
[PMID] 28940643.
2017
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
Nature genetics.
[DOI] 10.1038/ng.3874.
[PMID] 28530674.
2017
Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.
Journal of the American Heart Association.
[DOI] 10.1161/JAHA.117.006522.
[PMID] 29097388.
2017
Genetic variation at 16q24.2 is associated with small vessel stroke.
Annals of neurology.
[DOI] 10.1002/ana.24840.
[PMID] 27997041.
2017
Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.
Hypertension (Dallas, Tex. : 1979).
[PMID] 27802415.
2017
Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.
Circulation. Cardiovascular genetics.
[DOI] 10.1161/CIRCGENETICS.116.001404.
[PMID] 28115488.
2017
Genome-wide study of resistant hypertension identified from electronic health records.
PloS one.
[DOI] 10.1371/journal.pone.0171745.
[PMID] 28222112.
2017
Impact of the CYP2C19 genotype on voriconazole exposure in adults with invasive fungal infections.
Pharmacogenetics and genomics.
[DOI] 10.1097/FPC.0000000000000277.
[PMID] 28306618.
2017
Institutional profile: University of Florida Health Personalized Medicine Program.
Pharmacogenomics.
[DOI] 10.2217/pgs-2017-0028.
[PMID] 28346068.
2017
Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes).
Stroke.
[DOI] 10.1161/STROKEAHA.116.015936.
[PMID] 28351962.
2017
Relations Between Lipoprotein(A) Concentrations, Lpa Genetic Variants, and the Risk of Mortality in Patients With Established Coronary Heart Disease: a Molecular and Genetic Association Study
Lancet Diabetes and Endocrinology.
[DOI] 10.1016/S2213-8587(17)30096-7.
[PMID] 28566218.
2017
Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.
Journal of the American Heart Association.
[DOI] 10.1161/JAHA.117.006656.
[PMID] 29288159.
2017
Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.
Scientific reports.
[DOI] 10.1038/s41598-017-16343-z.
[PMID] 29167564.
2016
A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.
Hypertension (Dallas, Tex. : 1979).
[DOI] 10.1161/HYPERTENSIONAHA.116.07328.
[PMID] 27381900.
2016
CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril.
European journal of clinical pharmacology.
[DOI] 10.1007/s00228-016-2029-x.
[PMID] 26915813.
2016
Comparison of Blood Pressure Control Rates Among Recommended Drug Selection Strategies for Initial Therapy of Hypertension.
American journal of hypertension.
[DOI] 10.1093/ajh/hpw067.
[PMID] 27365079.
2016
CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.
Journal of neurosurgery.
[DOI] 10.3171/2015.6.JNS15795.
[PMID] 26587656.
2016
Effects of Using Personal Genotype Data on Student Learning and Attitudes in a Pharmacogenomics Course.
American journal of pharmaceutical education.
[PMID] 27756930.
2016
Genetic and Non-Genetic Factors Affecting Clopidogrel Efficacy in Egyptian Population
.
2016
Hypertension Pharmacogenomics: In Search of Personalized Treatment Approaches
.
2016
Hypertension pharmacogenomics: in search of personalized treatment approaches.
Nature reviews. Nephrology.
[DOI] 10.1038/nrneph.2015.176.
[PMID] 26592190.
2016
Identification of Additional Risk Loci for Stroke and Small Vessel Disease: A Meta-Analysis of Genome Wide Association Studies
Lancet Neurology.
2016
Identification of Suitable Endogenous Normalizers for qRT-PCR Analysis of Plasma microRNA Expression in Essential Hypertension.
Molecular biotechnology.
[DOI] 10.1007/s12033-015-9912-z.
[PMID] 26798072.
2016
Impact of GGCX, STX1B, and FPGS Polymorphisms on Warfarin Dose Requirements in European Americans and Egyptians
.
2016
Implementation of inpatient models of pharmacogenetics programs.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
[PMID] 27864202.
2016
Mechanisms and pharmacogenetic signals underlying thiazide diuretics blood pressure response.
Current opinion in pharmacology.
[DOI] 10.1016/j.coph.2016.01.005.
[PMID] 26874237.
2016
Melatonin Pathway and Atenolol-Related Glucose Dysregulation- Is There a Correlation?
.
2016
Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach.
Metabolomics : Official journal of the Metabolomic Society.
[DOI] 10.1007/s11306-016-1076-8.
[PMID] 28217400.
2016
Pharmacists should jump onto the clinical pharmacogenetics train.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
[PMID] 27864209.
2016
Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure Response to β-Blockers in Hypertensive African Americans.
Hypertension (Dallas, Tex. : 1979).
[DOI] 10.1161/HYPERTENSIONAHA.115.06345.
[PMID] 26729753.
2016
Population-Specific Single Nucleotide Polymorphism Confers Increased Risk of Venous Thromboembolism in African Americans
.
2016
Population-specific single-nucleotide polymorphism confers increased risk of venous thromboembolism in African Americans.
Molecular genetics & genomic medicine.
[DOI] 10.1002/mgg3.226.
[PMID] 27652279.
2016
Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol.
Metabolomics : Official journal of the Metabolomic Society.
[DOI] 10.1007/s11306-016-1098-2.
[PMID] 28217401.
2016
The IGNITE network: a model for genomic medicine implementation and research.
BMC medical genomics.
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2009
CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response.
Circulation. Cardiovascular genetics.
[DOI] 10.1161/CIRCGENETICS.109.857839.
[PMID] 20031608.
2009
Chromosome 7 and 19 trisomy in cultured human neural progenitor cells.
PloS one.
[DOI] 10.1371/journal.pone.0007630.
[PMID] 19898616.
2009
Cxcl5/Ena-78 Genotype and Progression To Death Or Transplantation in Heart Failure Patients.
Clinical Pharmacology & Therapeutics.
2009
Data Trends and Results From An Hlb Testing Laboratory That Has Processed Over 64,000 Commercial and Research Samples Over a Two Year Period in Florida
Phytopathology.
2009
Estimation of the Warfarin Dose With Clinical and Pharmacogenetic Data
New England Journal of Medicine.
2009
Genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure, and cardiovascular events in hypertension.
American journal of hypertension.
[DOI] 10.1038/ajh.2009.81.
[PMID] 19407804.
2009
Genotyping the GGGCGG tandem repeat promoter polymorphism in the 5-lipoxygenase enzyme gene (ALOX5) by pyrosequencing assay.
Genetic testing and molecular biomarkers.
[DOI] 10.1089/gtmb.2008.0103.
[PMID] 19473080.
2009
Hydrochlorothiazide and Atenolol Combination Antihypertensive Therapy: Effects of Drug Initiation Order
Clinical Pharmacology & Therapeutics.
[DOI] 10.1038/clpt.2009.101.
[PMID] 19571804.
2009
Lack of correlation between thiazide-induced hyperglycemia and hypokalemia: subgroup analysis of results from the pharmacogenomic evaluation of antihypertensive responses (PEAR) study
Pharmacotherapy.
[DOI] 10.1592/phco.29.10.1157.
[PMID] 19792989.
2009
Lack of correlation between thiazide-induced hyperglycemia and hypokalemia: subgroup analysis of results from the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.
Pharmacotherapy.
[DOI] 10.1592/phco.29.10.1157.
[PMID] 19792989.
2009
Long-Term Mortality Associated With New Onset Diabetes in Hypertensive Cad Patients Following Exposure To Antihypertensive Medications: Findings From the International Verapamail Sr-Trandolapril Study (Invest)
Journal of the American College of Cardiology.
2009
Pharmacogenomics of antihypertensive drugs: rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study.
American heart journal.
[DOI] 10.1016/j.ahj.2008.11.018.
[PMID] 19249413.
2009
Promoter Polymorphisms in Ace (Angiotensin I-Converting Enzyme) Associated With Clinical Outcomes in Hypertension
Clinical Pharmacology & Therapeutics.
[DOI] 10.1038/clpt.2008.194.
[PMID] 18946466.
2009
Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril.
Biochemical pharmacology.
[DOI] 10.1016/j.bcp.2008.12.017.
[PMID] 19185566.
2009
Systolic blood pressure and subjective well-being in patients with coronary artery disease.
Clinical cardiology.
[DOI] 10.1002/clc.20501.
[PMID] 19711440.
2009
Very important pharmacogene summary: sulfotransferase 1A1.
Pharmacogenetics and genomics.
[DOI] 10.1097/FPC.0b013e32832e042e.
[PMID] 19451861.
2009
Warfarin Pharmacogenetics Reply
New England Journal of Medicine.
2008
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.
Blood.
[DOI] 10.1182/blood-2008-01-134247.
[PMID] 18535201.
2008
A Polymorphism in the Nppa Gene Associates With Asthma
Clinical and Experimental Allergy.
[DOI] 10.1111/j.1365-2222.2008.02955.x.
[PMID] 18294255.
2008
A summer research training program to foster PharmD students’ interest in research.
American journal of pharmaceutical education.
[PMID] 18483591.
2008
Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation.
Journal of translational medicine.
[DOI] 10.1186/1479-5876-6-11.
[PMID] 18331634.
2008
Alpha-adducin polymorphism associated with increased risk of adverse cardiovascular outcomes: results from GENEtic Substudy of the INternational VErapamil SR-trandolapril STudy (INVEST-GENES).
American heart journal.
[DOI] 10.1016/j.ahj.2008.03.007.
[PMID] 18657677.
2008
Association of beta1-adrenergic receptor genetic polymorphism with mental stress-induced myocardial ischemia in patients with coronary artery disease.
Archives of internal medicine.
[DOI] 10.1001/archinte.168.7.763.
[PMID] 18413560.
2008
B1-Adrenergic Receptor Polymorphism Predicts Mental Stress-Induced Myocardial Ischemia in Patients With Coronary Artery Disease
Journal of the American College of Cardiology.
2008
Beta-Adrenergic Receptor Gene Polymorphisms and Beta-Blocker Treatment Outcomes in Hypertension
Clinical Pharmacology & Therapeutics.
[DOI] 10.1038/clpt.2008.139.
[PMID] 18615004.
2008
Beta-adrenergic receptor gene polymorphisms and hemodynamic response to dobutamine during dobutamine stress echocardiography.
The pharmacogenomics journal.
[DOI] 10.1038/sj.tpj.6500490.
[PMID] 18253135.
2008
Creating and evaluating genetic tests predictive of drug response.
Nature reviews. Drug discovery.
[DOI] 10.1038/nrd2520.
[PMID] 18587383.
2008
CYP4F2 genetic variant alters required warfarin dose.
Blood.
[DOI] 10.1182/blood-2007-11-122010.
[PMID] 18250228.
2008
Ethnic differences in cardiovascular drug response: potential contribution of pharmacogenetics.
Circulation.
[DOI] 10.1161/CIRCULATIONAHA.107.704023.
[PMID] 18809808.
2008
Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia.
Pharmacogenetics and genomics.
[DOI] 10.1097/FPC.0b013e3282fc5801.
[PMID] 18496130.
2008
Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement.
Blood.
[DOI] 10.1182/blood-2008-03-144899.
[PMID] 18523153.
2008
Simplified method for determination of clarithromycin in human plasma using protein precipitation in a 96-well format and liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[DOI] 10.1016/j.jchromb.2008.06.050.
[PMID] 18639501.
2008
Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis.
American journal of human genetics.
[DOI] 10.1016/j.ajhg.2008.04.015.
[PMID] 18485328.
2008
Use of Pharmacogenetic and Clinical Factors To Predict the Therapeutic Dose of Warfarin
Clinical Pharmacology & Therapeutics.
[DOI] 10.1038/clpt.2008.10.
[PMID] 18305455.
2008
Vkorc1 and Cyp2C9 Polymorphisms Are Associated With Warfarin Dose Requirements in Turkish Patients
European journal of clinical pharmacology.
[DOI] 10.1007/s00228-008-0507-5.
[PMID] 18542936.
2008
Warfarin: an old drug but still interesting.
Pharmacotherapy.
[DOI] 10.1592/phco.28.9.1081.
[PMID] 18752378.
2007
Assessment of Human Serotonin 1A Receptor Polymorphisms and SSRI Responsiveness
.
2007
Assessment of human serotonin 1A receptor polymorphisms and SSRI responsiveness.
Molecular diagnosis & therapy.
[PMID] 17570737.
2007
Association of CYP3A5 Polymorphisms with Hypertension and Antihypertensive Response to Verapamil
Clinical Pharmacology & Therapeutics.
2007
Association of Diurnal Blood Pressure Pattern with Risk for Hospitalization or Death in Men with Heart Failure
.
2007
Association of diurnal blood pressure pattern with risk of hospitalization or death in men with heart failure.
Journal of cardiac failure.
[PMID] 17923358.
2007
Cytochrome P4502D6 (CYP2D6) Gene Locus Heterogeneity: Characterization of Gene Duplication Events
Clinical Pharmacology & Therapeutics.
2007
Epistatic Control of Human Obesity as Revealed by Linkage Disequilibrium Mapping: a Report from the NHLBI-Sponsored WISE Study
.
2007
Factors influencing blood pressure response to trandolapril add-on therapy in patients taking verapamil SR (from the International Verapamil SR/Trandolapril [INVEST] Study).
The American journal of cardiology.
[PMID] 17531579.
2007
Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing.
Pharmacogenomics.
[PMID] 17465717.
2007
KCNMB1 Genotype Influences Response to Verapamil SR and Adverse Outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST)
.
2007
KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST).
Pharmacogenetics and genomics.
[PMID] 17700361.
2007
Modeling sequence-sequence interactions for drug response.
Bioinformatics (Oxford, England).
[PMID] 17392331.
2007
Modeling Sequence-Sequence Interactions of Drug Response
.
2007
PharmGKB Submission Update: IX. ADRB1 Gene Summary
.
2007
PharmGKB submission update: IX. ADRB1 gene summary.
Pharmacological reviews.
[PMID] 17329544.
2007
Relation of beta(2)-adrenoceptor haplotype to risk of death and heart transplantation in patients with heart failure.
The American journal of cardiology.
[PMID] 17223428.
2007
Single Nucleotide Polymorphism Discovery and Haplotype Analysis of Ca2+ -Dependent K+ Channel Beta-1 Subunit
.
2007
Single nucleotide polymorphism discovery and haplotype analysis of Ca2+-dependent K+ channel beta-1 subunit.
Pharmacogenetics and genomics.
[PMID] 17496725.
2007
Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure.
Pharmacogenetics and genomics.
[PMID] 17496726.
2007
Synergistic Polymorphisms of Beta1- and Alpha2c-Adrenergic Receptors and the Influence on Left Ventricular Ejection Fraction Response to Beta-Blocker Therapy in Heart Failure
.
2007
The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response
Clinical Pharmacology & Therapeutics.
2006
A Bivariate Functional Mapping Model for Identifying Haplotypes that Control Drug Response for Systolic and Diastolic Blood Pressures
Pacific Symposium on Biocomputing.
2006
Discordant beta-blocker effects on clinic, ambulatory, resting, and exercise hemodynamics in patients with hypertension.
Pharmacotherapy.
[PMID] 16945046.
2006
Genetic Determinants of -Blocker Response: Influence of Phenotype and Pharmacokinetics on Drug Target Pharmacogenetics
.
2006
Highly Variable mRNA Expression and Splicing of L-Type Voltage-Dependent Calcium Channel Alpha Subunit 1c (CACNA1C) in Human Heart Tissues
.
2006
Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues.
Pharmacogenetics and genomics.
[PMID] 17001293.
2006
Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochrome P450 2C9 gene polymorphisms on warfarin dose requirements.
Clinical pharmacology and therapeutics.
[PMID] 16580898.
2006
Pharmacogenetics of chronic cardiovascular drugs: applications and implications.
Expert opinion on pharmacotherapy.
[PMID] 16859425.
2006
Pharmacogenomics: Challenges and Opportunities
.
2006
Pharmacogenomics: challenges and opportunities.
Annals of internal medicine.
[PMID] 17116919.
2006
Re: Meckley LM, Veenstra DL. Screening for the alpha-adducin Gly460Trp variant in hypertensive patients: a cost-effectiveness analysis. Pharmacogenet Genom 2006; 16:139-147.
Pharmacogenetics and genomics.
[PMID] 16847430.
2006
Sustained Restoration of Autonomic Balance with Long- but not Short-Acting Metoprolol in Patients with Heart Failure
.
2006
Sustained restoration of autonomic balance with long- but not short-acting metoprolol in patients with heart failure.
Journal of cardiac failure.
[PMID] 16624680.
2005
A Pharmacodynamic Model of the Effects of Controlled-Onset Extended-Release Verapamil on 24 Hour Ambulatory Blood Pressure
.
2005
Association between beta-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study
International Journal of Obesity.
[DOI] 10.1016/j.cancergencyto.2004.08.016.
[PMID] 15917856.
2005
beta-Adrenergic receptor polymorphisms and responses during titration of metoprolol controlled release/extended release in heart failure.
Clinical pharmacology and therapeutics.
[PMID] 15735607.
2005
Beta1-Adrenergic Receptor Polymorphisms and Left Ventricular Remodeling Changes in Response to Beta-Blocker Therapy
.
2005
Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy.
Pharmacogenetics and genomics.
[PMID] 15864115.
2005
Hypertension pharmacogenomics: current status and future directions.
Current opinion in molecular therapeutics.
[PMID] 15977418.
2005
Sequencing Drug Response with HapMap
.
2005
Use of pharmacogenetics in clinical medicine: hype or hope?
Personalized medicine.
[DOI] 10.2217/17410541.2.4.279.
[PMID] 29788574.
2004
A Statistical Model for Functional Mapping of Quantitative Trait Loci Regulating Drug Response
.
2004
Caution with 1-Adrenergic Receptor Genotyping
Clinical Pharmacology & Therapeutics.
2004
Comparison of cytochrome P450 2C9 genotyping methods and implications for the clinical laboratory.
Pharmacotherapy.
[PMID] 15222661.
2004
Differences in Drug Pharmacokinetics Between East Asians and Caucasians and the Role of Genetic Polymorphisms
.
2004
Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.
Journal of clinical pharmacology.
[PMID] 15342610.
2004
Influence of gender and race on hemodynamic response to dobutamine during dobutamine stress echocardiography.
The American journal of cardiology.
[PMID] 15325950.
2004
Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension.
Clinical pharmacology and therapeutics.
[PMID] 15592325.
2003
A haplotype-based algorithm for multilocus linkage disequilibrium mapping of quantitative trait loci with epistasis.
Genetics.
[PMID] 12702696.
2003
Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol.
Clinical pharmacology and therapeutics.
[PMID] 12844134.
2003
Drug receptor/effector polymorphisms and pharmacogenetics: current status and challenges.
Pharmacogenetics.
[PMID] 12972951.
2003
Pharmacogenetics: potential for individualized drug therapy through genetics.
Trends in genetics : TIG.
[PMID] 14585618.
2003
The evolving role of nesiritide in advanced or decompensated heart failure.
Pharmacotherapy.
[PMID] 14594345.
2002
Beta-adrenergic receptor polymorphisms: cardiovascular disease associations and pharmacogenetics.
Pharmaceutical research.
[PMID] 12523655.
2002
Collection of genomic DNA by the noninvasive mouthwash method for use in pharmacogenetic studies.
Pharmacotherapy.
[PMID] 12173798.
2002
Dobutamine pharmacodynamics during dobutamine stress echocardiography and the impact of beta-blocker withdrawal: a report from the Women’s Ischemic Syndrome Evaluation Study.
Pharmacotherapy.
[PMID] 12173796.
2002
Molecular diagnostics as a predictive tool: genetics of drug efficacy and toxicity.
Trends in molecular medicine.
[PMID] 12067617.
2002
Pharmacogenetics of cardiovascular drugs.
Briefings in functional genomics & proteomics.
[PMID] 15251067.
2002
Pharmacogenetics, pharmacogenomics, and cardiovascular therapeutics: the way forward.
American journal of cardiovascular drugs : drugs, devices, and other interventions.
[PMID] 14727958.
2002
Pharmacogenomics: A Scientific Revolution in Pharmaceutical Sciences and Pharmacy Practice. Report of the 2001/02 Academic Affairs Committee
American Journal of Pharmaceutical Education.
2001
Determination of Human Beta2-Adrenoceptor Haplotypes by Denaturation Selective Amplification and Subtractive Genotyping
.
2001
Drug target pharmacogenomics: an overview.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.
[PMID] 12083959.
2001
Effects of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia
American Journal of Cardiology.
[DOI] 10.1016/S0002-9149(01)01986-5.
[PMID] 11704005.
2001
INVEST Substudies: Design and Patient Characteristics
Clinical Cardiology.
2001
Pharmacogenomics: The Inherited Basis for Inter-Individual Differences in Drug Response
.
2001
The Effect of Gut Metabolism on Tacrolimus Bioavailability in Renal Transplant Recipients
.
2000
CYP1A2 and CYP2D6 4-hydroxylate propranolol and both reactions exhibit racial differences.
Journal of Pharmacology and Experimental Therapeutics.
[PMID] 10945865.
2000
Effects of COER-Verapamil on Circadian Pattern of Forearm Vascular Resistance and Blood Pressure
.
2000
Gender Differences in Labetalol Kinetics: Importance of Determining Stereoisomer Kinetics for Racemic Drugs
Pharmacotherapy.
2000
Importance of Beta2 Adrenergic Receptor Genotype, Gender and Race on Albuterol-Evoked Bronchodilation in Asthmatics
Pulmonary Pharmacology & Therapeutics.
2000
Predictability of the Effects of Race or Ethnicity on Pharmacokinetics of Drugs (Invited Review)
.
2000
Sequencing of Beta2-Adrenoceptor Gene PCR Products Using Taq BigDye Terminator Chemistry Results in Inaccurate Base-Calling
Biotechniques.
2000
Simple Method for Determination of Terbutaline Plasma Concentration by High Performance Liquid Chromatography
.
1999
Effects of Gender and Race on Albuterol Pharmacokinetics
Pharmacotherapy.
1999
Impact of Genetic Polymorphisms of the Beta2-Adrenergic Receptor on Albuterol Bronchodilator Pharmacodynamics
Clinical Pharmacology & Therapeutics.
1999
Intranasal DDAVP-Induced Increases in Plasma Von Willebrand Factor Alter the Pharmacokinetics of High-Purity Factor VIII Concentrates in Severe Hemophilia A Patients
.
1998
The Role of Endothelin-1 in Heart Failure and Hypertension
Pharmacotherapy.
1997
Differences Between Blacks and Whites in Plasma Protein Binding of Drugs
.
1997
Influence of Race or Ethnicity on Pharmacokinetics of Drugs
Journal of Pharmaceutical Sciences.
1996
Metoprolol Metabolism Via Cytochrome P450 2D6 in Ethnic Populations
.
1996
Racial Differences in Propranolol Enantiomer Kinetics Following Simultaneous IV and Oral Administration
British Journal of Clinical Pharmacology.
1995
Influence of Metabolites on Protein Binding of Verapamil Enantiomers
British Journal of Clinical Pharmacology.
1995
Lymphocyte Beta2-Receptor Activity, Metoprolol Kinetics and Response to Metoprolol in Hypertensive Black Men
Pharmacotherapy.
1995
Metoprolol Minimizes Nighttime Blood Pressure Dip in Hypertensive Black Males
American Journal of Hypertension.
1995
Racial Differences in Beta-Adrenoceptor-Mediated Responsiveness
Journal of Cardiovascular Pharmacology.
1995
Racial Differences in Sensitivity to the Negative Chronotropic Effects of Propranolol in Healthy Males
Clinical Pharmacology & Therapeutics.
1993
Differences in Apparent Sensitivities of Chronotropy and Inotropy to Propranolol
.
1993
Direct High Performance Liquid Chromatographic Determination in Urine of the Enantiomers of Propranolol and its Major Basic Metabolite 4-Hydroxypropranolol
Journal of Chromatography a.
1993
Racial Differences in Lymphocyte Beta-Receptor Sensitivity to Propranolol
Life Sciences.
1992
Racial Differences in Propranolol Pharmacokinetics
Clinical Pharmacology & Therapeutics.
1991
Diastolic Dysfunction in Congestive Heart Failure
.
1990
Comparison of Hypersensitivity to Adrenergic Stimulation After Abrupt Withdrawal of Propranolol and Nadolol: Influence of Half-Life Differences
.
1990
Comparison of Single Dose and Steady State Nadolol Plasma Concentrations
Pharmaceutical Research.
1990
Use of Beta-Adrenergic Blocking Agents in Congestive Heart Failure
.
1989
Biphasic Pattern of Hypersensitivity Following Acute Propranolol Withdrawal in Normal Subjects
Life Sciences.
1989
Drug- or Hormone-Induced Adaptation: Model of Adrenergic Hypersensitivity
Journal of Pharmacokinetics and Pharmacodynamics.
1987
Lovastatin: A New Cholesterol Lowering Agent
Pharmacotherapy.
1986
Dose- and Time-Dependent Binding and Kinetics of Pindolol in Patients with Congestive Heart Failure
.
1986
Management of Pediatric Patients with Bronchiolitis in the Emergency Department
.
1985
Management of Bronchiolitis
.
1985
Prophylactic Antibiotics in Plastic Surgery
.
Grants
Dec 2021
ACTIVE
Impact of CYP2D6 genotypes and inhibitors on opioid therapy in patients with pain
Role: Other
Funding: AMER COL OF CLINICAL PHAR
Sep 2021
ACTIVE
Warfarin Pharmacogenetics at UF Health
Role: Co-Investigator
Funding: UF HEALTH SHANDS HOSPITAL
Jan 2020
– Dec 2021
Personalizing thiazide therapy through clinical and microRNA biomarkers of response to thiazides
Role: Other
Funding: AMER HEART ASSOCIATION
Sep 2018
ACTIVE
Sparking Advancements in Genomic Medicine?
Role: Principal Investigator
Funding: NATL INST OF HLTH NHGRI
Jan 2018
ACTIVE
Training Program for Applied Research and Development in Genomic Medicine
Role: Principal Investigator
Funding: NATL INST OF HLTH NHGRI
Jul 2016
– Sep 2020
A stem cell tactic to promote personalized medicine
Role: Project Manager
Funding: NATL INST OF HLTH NIGMS
Jul 2016
– Jun 2018
A Stem Cell Tactic to Promote Personalized Medicine in Hypertension
Role: Faculty
Funding: AMER HEART ASSOCIATION
Oct 2015
– Mar 2019
OneFlorida Clinical Research Consortium Phase II
Role: Project Manager
Funding: PATIENT-CENTERED OUTCOMES RES INST
Jul 2014
– Dec 2015
Using Different OMICS for the Identification of Novel Biomarkers of Blood Pressure Response to Antihypertensive Drugs
Role: Principal Investigator
Funding: AMER HEART ASSOCIATION
Jun 2013
– Sep 2018
Genomic Medicine Implementation: The Personalized Medicine Program
Role: Principal Investigator
Funding: NATL INST OF HLTH NHGRI
Mar 2011
– Feb 2016
Secondary Prevention of Subcortical Stroke Prevention Genetics Substudy Timing
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Aug 2010
– Jul 2017
Pharmacogenomic Evaluation of Antihypertensive Responses.
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Jul 2007
– Aug 2016
Clinical and Translational Science Institute
Role: Project Manager
Funding: UF RESEARCH FOU
Contact Details
Phones:
- Business:
- (352) 273-6309
Emails:
- Business:
- julie.johnson@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100484
GAINESVILLE FL 32610 - Business Street:
-
1225 CENTER DR
HPNP 4332
GAINESVILLE FL 326103007