Guenther Hochhaus

Guenther Hochhaus, Ph.D.

Professor

Department: Pharmaceutics
Business Phone: (352) 273-7861
Business Email: hochhaus@cop.ufl.edu

About Guenther Hochhaus

Hochhaus evaluates anti-asthma drugs in the body (pharmacokinetics) to understand the relationship between the drug properties and the pharmacodynamic effects. His work linking pharmacokinetic-pharmacodynamic approaches with a rational drug delivery design has proven to be a powerful tool in streamlining drug development for inhalation drugs. To provide a strong research program in pharmaceutics and actively seek outside support; to participate in teaching and education of undergraduate, graduate students and postdoctoral associates. The courses include undergraduate class “Principles of Dose Optimization I (PHA 5127)”, and graduate class “Pharmaceutical Analysis I (PHA 6416)”.

Publications

2019 European Journal of Pharmaceutical Sciences
2013 Journal of Aerosol Medicine and Pulmonary Drug Delivery
2012 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
2011 The Journal of allergy and clinical immunology
2009 Drug metabolism and disposition: the biological fate of chemicals
2008 Drugs of today (Barcelona, Spain : 1998)
2006 International journal of clinical pharmacology and therapeutics
2006 Drug metabolism and disposition: the biological fate of chemicals
2005 The Journal of pharmacy and pharmacology
2005 Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
2004 International journal of clinical pharmacology and therapeutics
2004 Proceedings of the American Thoracic Society
2004 Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
2002 Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
2001 Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine
2001 Pharmaceutical research
1999 International journal of clinical pharmacology and therapeutics
1998 Journal of pharmaceutical and biomedical analysis
1998 International journal of clinical pharmacology and therapeutics
1998 The Journal of allergy and clinical immunology
1997 Journal of pharmaceutical and biomedical analysis
1997 International journal of clinical pharmacology and therapeutics
1996 International journal of clinical pharmacology and therapeutics
1996 Neurochemical research
1993 Skin pharmacology : the official journal of the Skin Pharmacology Society
1992 International journal of clinical pharmacology, therapy, and toxicology
1992 International journal of clinical pharmacology, therapy, and toxicology
1991 Journal of pharmaceutical and biomedical analysis
1990 Journal of pharmaceutical and biomedical analysis
1983 Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie

Grants

Oct 2020 – Oct 2020
GSK Fellowship – Jose Francis Year 2
GLAXO SMITHKLINE · Mentor
Oct 2019 – Jul 2020
GSK Fellowship – Jose Francis Year 1
GLAXO SMITHKLINE · Principal Investigator
Sep 2019 ACTIVE
Systematic evaluation of the ex-throat plume properties of MDI formulations
US FOOD AND DRUG ADMN · Principal Investigator
Sep 2019 ACTIVE
A Multiscale Computational Framework for Bioequivalence of Orally Inhaled Drugs
CFD RESEARCH CORP · Principal Investigator
Jul 2019 – Jul 2020
Clinical Pharmacokinetics/Dynamics Fellowship 2018-2019 – Sagar Bachav
GLAXO SMITHKLINE · Principal Investigator
Jul 2018 – Jul 2019
Clinical Pharmacokinetics/Dynamics Fellowship 2017-2018 – Sagar Bachav
GLAXO SMITHKLINE · Principal Investigator
Sep 2016 – Mar 2018
Pharmacokinetic Comparison of Locally Acting Orally Inhaled Drug Products
US FOOD AND DRUG ADMN ·
Feb 2016 – Dec 2016
Methacholine stability test over 8 months (months 0-8)-batch 2
COMPLEWARE CORPORATION · Principal Investigator
Aug 2015 – Nov 2016
Methacholine Stability Testing with Ion
COMPLEWARE CORPORATION · Principal Investigator
Jul 2015 – Jan 2017
Further Characterization of the Modified Chi-square Rati
INTL PHARM AEROSOL CONSRT REG AND SCIENC · Principal Investigator
Apr 2015 ACTIVE
Peptidic Kappa Opioid Receptor Ligands as Potential Treatments for Drug Addiction
NATL INST OF HLTH NIDA · Project Manager
Mar 2015 – Dec 2018
Determination of Drug Levels in Interstitial Fluid for Therapeutic IgG by Microdialysis and its Relevance for Pharmacokinetic and Pharmacodynamic
HOFFMANN LA ROCHE · Principal Investigator
Dec 2014 – Feb 2020
Comprehensive Evaluation of Formulation Effects on Metered Dose Inhaler Performance
US FOOD AND DRUG ADMN · Principal Investigator
Sep 2013 – Apr 2020
Study to Investigate the Sensitivity of Pharmacokinetics in Detecting Differences in Physicochemical Properties of the Active in Suspension Nasal Products for Local Action
US FOOD AND DRUG ADMN ·
Sep 2013 – Dec 2016
Stability of Fluticasone Proprionate Capsules for Inhala
FEFA · Principal Investigator
Sep 2013 – Feb 2017
Development of In Vivo Predictive Dissolution Method for
US FOOD AND DRUG ADMN · Principal Investigator
Aug 2012 – Jul 2017
Does P-glycoprotein Restrict Access of Budesonide but not Fluticasone Propionate to the Placenta and Fetus?
ASTRAZENECA · Principal Investigator
Sep 2011 – Sep 2016
Pharmacokinetic Comparison of Locally Acting Inhaled
FEFA · Principal Investigator

Patents

Issued November 2001
Development of a Bootstrap Application for Resampling Pharmacokinetic and Toxicokinetic Data.
#Tu1021748
Issued January 2006
Methods for Preparing Coated Drug Particles and Pharmaceutical Formulations Thereof
#6,984,404

Education

Ph.D.
1984 · University of Munster
B.Sc.
1980 · Elisabeth Apotheke

Contact Details

Phones:
Business:
(352) 273-7861
Emails: