Joshua Brown

Joshua Brown, Pharm.D., Ph.D., M.S.

Assistant Professor

Department: Pharmaceutical Outcomes & Policy
Business Phone: (352) 294-8593
Business Email: joshua.brown@cop.ufl.edu

About Joshua Brown

Joshua Brown joined the Department of Pharmaceutical Outcomes and Policy as an assistant professor in 2016. He has experience in clinical pharmacy, health economics and outcomes research, and pharmacoepidemiology across academic, pharmaceutical industry, and managed care. His past and ongoing clinical interests have been in the cardiovascular and hematology/oncology therapeutic areas including comparative effectiveness and safety research with a focus on anticoagulation and quality of care in thrombotic conditions such as atrial fibrillation, venous thromboembolism, and cancer. His current research program and collaborations focus on research methods for pharmacoepidemiologic and pharmacoeconomic generic and biosimilar evaluations, developing real-world evidence for drug-drug interactions, and drug repurposing studies (e.g. aging and Parkinson’s Disease). \His academic work has been funded by the NIH, FDA, Bill & Melinda Gates Foundation, and the PhRMA Foundation in addition to contracts with pharmaceutical industry. Josh has published over 100 research articles and holds several editorial positions with high impact specialty journals in pharmacy and cardiovascular diseases and is actively involved in AMCP, ISPE, and ISPOR scientific societies. Dr. Brown was awarded as the AMCP Foundation’s “New Practitioner” for his early career contributions to managed care pharmacy.

Accomplishments

New Practitioner Award
2019 · Academy of Managed Care Pharmacy
Emerging Leader
2019 · National Academy of Medicine
Loan Repayment Program
2018-2020 · NIH – National Institute on Aging
Claude D. Pepper Junior Scholar
2017-2019 · UF Institute on Aging

Publications

2021
Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine.
Research in social & administrative pharmacy : RSAP. 17(2):483-486 [DOI] 10.1016/j.sapharm.2020.04.016. [PMID] 32327397.
2021
Three-Year, Postintervention, Follow-up Comparison of Health Care Resource Utilization and Costs in the Lifestyle Interventions and Independence for Elders (LIFE) Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(2):272-276 [DOI] 10.1093/gerona/glaa088. [PMID] 32270182.
2020
Application of a Graphical Depiction of Longitudinal Study Designs to Managed Care Pharmacy Research.
Journal of managed care & specialty pharmacy. 26(3):268-274 [DOI] 10.18553/jmcp.2020.26.3.268. [PMID] 32105168.
2020
Quantitative Benefit-Risk Assessment of P-gp Mediated Drug-Drug Interactions (DDIs) of Dabigatran Co-Administered with Pharmacokinetic Enhancers in Patients with Renal Impairment
Clinical Pharmacology & Therapeutics. 109(1):193-200 [DOI] 10.1002/cpt.2087. [PMID] 33073366.
2020
Potential Adverse Drug Events with Tetrahydrocannabinol (THC) Due to Drug-Drug Interactions.
Journal of clinical medicine. 9(4) [DOI] 10.3390/jcm9040919. [PMID] 32230864.
2020
Perception of prescription drug monitoring programs as a prevention tool in primary medical care.
Research in social & administrative pharmacy : RSAP. 16(9):1306-1308 [DOI] 10.1016/j.sapharm.2019.03.012. [PMID] 30935769.
2020
OB/GYN perceptions of prescription drug monitoring programs as a primary prevention tool for neonatal abstinence syndrome.
Research in social & administrative pharmacy : RSAP. 16(12):1789-1791 [DOI] 10.1016/j.sapharm.2020.03.010. [PMID] 32265114.
2020
Missed opportunities for pneumococcal vaccinations in high-risk and older adults in the United States.
Journal of infection and public health. 13(1):101-103 [DOI] 10.1016/j.jiph.2019.06.010. [PMID] 31279802.
2020
Machine Learning in Drug Discovery and Development Part 1: A Primer.
CPT: pharmacometrics & systems pharmacology. 9(3):129-142 [DOI] 10.1002/psp4.12491. [PMID] 31905263.
2020
A pharmacoepidemiologic approach to evaluate real-world effectiveness of hormonal contraceptives in the presence of drug-drug interactions
Epidemiology. 32(2):268-276 [DOI] 10.1097/EDE.0000000000001302. [PMID] 33196560.
2020
Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study
Journal of Clinical Medicine. 9(9) [DOI] 10.3390/jcm9092989. [PMID] 32947839.
2020
Healthcare Utilization and Physical Functioning in Older Adults in the United States.
Journal of the American Geriatrics Society. 68(2):266-271 [DOI] 10.1111/jgs.16260. [PMID] 31755551.
2020
Comparative Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Response to a Physical Activity Intervention in Older Adults: Results From the Lifestyle Interventions and Independence for Elders Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(5):1010-1016 [DOI] 10.1093/gerona/glz120. [PMID] 31070702.
2020
Characteristics of Older Adults Who Were Early Adopters of Medical Cannabis in the Florida Medical Marijuana Use Registry.
Journal of clinical medicine. 9(4) [DOI] 10.3390/jcm9041166. [PMID] 32325769.
2020
Atopic Disease and Anemia in Korean Patients: Cross-Sectional Study with Propensity Score Analysis.
International journal of environmental research and public health. 17(6) [DOI] 10.3390/ijerph17061978. [PMID] 32197291.
2020
Association of Oral Anticoagulants and Verapamil or Diltiazem With Adverse Bleeding Events in Patients With Nonvalvular Atrial Fibrillation and Normal Kidney Function.
JAMA network open. 3(4) [DOI] 10.1001/jamanetworkopen.2020.3593. [PMID] 32329770.
2020
Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study
Journal of Clinical Medicine. 9(11) [DOI] 10.3390/jcm9113757. [PMID] 33266358.
2020
Reliability and Validity of the Short-Form 12 Item Version 2 (SF-12v2) Health-Related Quality of Life Survey and Disutilities Associated with Relevant Conditions in the U.S. Older Adult Population.
Journal of clinical medicine. 9(3) [DOI] 10.3390/jcm9030661. [PMID] 32121371.
2020
Higher insulin expenditures associated with utilization of free medication samples.
Research in social & administrative pharmacy : RSAP. 16(9):1302-1305 [DOI] 10.1016/j.sapharm.2019.04.001. [PMID] 31027965.
2020
Risk of Opioid Overdose Associated With Concomitant Use of Opioids and Skeletal Muscle Relaxants: A Population-Based Cohort Study.
Clinical pharmacology and therapeutics. 108(1):81-89 [DOI] 10.1002/cpt.1807. [PMID] 32022906.
2020
Trajectories of Short Physical Performance Battery Are Strongly Associated with Future Major Mobility Disability: Results from the LIFE Study
Journal of Clinical Medicine. 9(8) [DOI] 10.3390/jcm9082332. [PMID] 32707877.
2020
Trends, Patient and Prescriber Characteristics in Gabapentinoid Use in a Sample of United States Ambulatory Care Visits from 2003 to 2016
Journal of Clinical Medicine. 9(1) [DOI] 10.3390/jcm9010083. [PMID] 31905718.
2020
Updating the Cost Effectiveness of Oral Anticoagulants for Patients with Atrial Fibrillation Based on Varying Stroke and Bleed Risk Profiles
Pharmacoeconomics. 38(12):1333-1343 [DOI] 10.1007/s40273-020-00960-0. [PMID] 32924092.
2020
What Do You Meme, Professor? An Experiment Using “Memes” in Pharmacy Education
Pharmacy (Basel). 8(4) [DOI] 10.3390/pharmacy8040202. [PMID] 33138086.
2020
Survey-reported medication changes among older adults during the SARS-CoV-2 (COVID-19) pandemic
Research in Social & Administrative Pharmacy. [DOI] 10.1016/j.sapharm.2020.11.005. [PMID] 33221267.
2019
Risk Factors Associated With 7- Versus 30-Day Readmission Among Patients With Heart Failure Using the Nationwide Readmission Database.
Medical care. 57(1):1-7 [DOI] 10.1097/MLR.0000000000001006. [PMID] 30363021.
2019
Real-World Data Approaches for Early Detection of Potential Safety and Effectiveness Signals for Generic Substitution: A Metoprolol Extended-Release Case Study.
Journal of clinical pharmacology. 59(9):1275-1284 [DOI] 10.1002/jcph.1436. [PMID] 31087552.
2019
Real-world adherence for direct oral anticoagulants in a newly diagnosed atrial fibrillation cohort: does the dosing interval matter?
BMC cardiovascular disorders. 19(1) [DOI] 10.1186/s12872-019-1033-3. [PMID] 30890131.
2019
Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use.
Journal of clinical medicine. 8(7) [DOI] 10.3390/jcm8070989. [PMID] 31288397.
2019
Pharmacometrics, Physiologically Based Pharmacokinetics, Quantitative Systems Pharmacology-What’s Next?-Joining Mechanistic and Epidemiological Approaches.
CPT: pharmacometrics & systems pharmacology. 8(6):352-355 [DOI] 10.1002/psp4.12425. [PMID] 31179639.
2019
Impact of Schedule IV controlled substance classification on carisoprodol utilization in the United States: An interrupted time series analysis.
Drug and alcohol dependence. 202:172-177 [DOI] 10.1016/j.drugalcdep.2019.05.025. [PMID] 31352307.
2019
Disparities in the Use of Cardiac Rehabilitation after a Myocardial Infarction in the United States.
Journal of clinical medicine. 8(7) [DOI] 10.3390/jcm8071006. [PMID] 31295853.
2019
Commentary on: Depression, antidepressant use, and risk of venous thromboembolism: systematic review and meta-analysis of published observational evidence.
Annals of medicine. 51(1):97-98 [DOI] 10.1080/07853890.2019.1581941. [PMID] 30801227.
2019
Central Nervous System Effects of Oral Propranolol for Infantile Hemangioma: A Systematic Review and Meta-Analysis.
Journal of clinical medicine. 8(2) [DOI] 10.3390/jcm8020268. [PMID] 30813242.
2019
Association of Adverse Drug Events with Hospitalization Outcomes and Costs in Older Adults in the USA using the Nationwide Readmissions Database.
Pharmaceutical medicine. 33(4):321-329 [DOI] 10.1007/s40290-019-00286-z. [PMID] 31933184.
2019
Effect of Gastric Acid Suppressants on Response to a Physical Activity Intervention and Major Mobility Disability in Older Adults: Results from the Lifestyle Interventions for Elders (LIFE) Study.
Pharmacotherapy. 39(8):816-826 [DOI] 10.1002/phar.2299. [PMID] 31230397.
2018
Risk Stratification for Bleeding Complications in Patients With Venous Thromboembolism: Application of the HAS-BLED Bleeding Score During the First 6 Months of Anticoagulant Treatment.
Journal of the American Heart Association. 7(6) [DOI] 10.1161/JAHA.117.007901. [PMID] 29514808.
2017
The Power and Pitfalls of Big Data Research in Obstetrics and Gynecology: A Consumer’s Guide.
Obstetrical & gynecological survey. 72(11):669-682 [DOI] 10.1097/OGX.0000000000000504. [PMID] 29164265.
2016
Impact of Time-Varying Treatment Exposures on the Risk of Venous Thromboembolism in Multiple Myeloma.
Healthcare (Basel, Switzerland). 4(4) [DOI] 10.3390/healthcare4040093. [PMID] 27999418.

Grants

Oct 2019 – Sep 2020
Quality of care for inferior vena cava filters at UF Health Shands Hospital
Role: Principal Investigator
Funding: UF HEALTH SHANDS HOSPITAL
Jul 2019 – Dec 2020
Consortium for Medical Marijuana Clinical Outcomes Research
Role: Project Manager
Funding: STATE UNIVERSITY SYSTEM OF FLORIDA via FL LEGISLATURE
Nov 2017 ACTIVE
Application of physiologically-based pharmacokinetic models to inform dosing recommendations for hormonal contraceptives co-administered with other medications
Role: Co-Investigator
Funding: GATES FOU, BILL & MELINDA
Sep 2017 – Feb 2019
Comparative effectiveness of direct-acting oral anticoagulants (DOACs) for stroke prevention in atrial fibrillation: Influence of study methods on the usefulness of the results in the real-world
Role: Principal Investigator
Funding: PHRMA FOU
Sep 2014 – Aug 2018
A Model- and Systems-based Approach to Efficacy and Safety Questions Related to Generic Substitution
Role: Co-Investigator
Funding: US FOOD AND DRUG ADMN

Education

Ph.D.
2016 · University of Kentucky
M.S.
2014 · University of Arkansas for Medical Science
Pharm.D.
2014 · University of Arkansas for Medical Science
B.S.
2010 · University of Arkansas

Teaching Profile

Courses Taught
2017-2020
PHA5223 P-Epidem Drug Safety
2017-2018,2020-2021
PHA7980 Research for Doctoral Dissertation
2017-2018,2020-2021
PHA6910 Supervised Research
2020-2021
PHA6805 Applied Data Interpretation and Reporting of Findings in Pharmacy
2017-2018,2020-2021
PHA7979 Advanced Research
2017,2020
PHA6935 Selected Topics in Pharmacy
2018-2021
PHA6265 Introduction to Pharmaceutical Outcomes and Policy I
2019-2021
PHA6940 Supervised Teaching
2017-2018,2020-2021
PHA6971 Research for Master’s Thesis
2017,2019-2021
PHA6936 Advanced Topics in Pharmaceutical Sciences
2017-2021
PHA6937 Topics in Pharmaceutical Administration
2017-2018
PHA5788C Patient Care 6
2018
PHA5166L Prof Skills Lab Vi
2017
PHA6266 Introduction to Pharmaceutical Outcomes and Policy II
2021
PHA5956 Special Topics/Self-Directed Study

Contact Details

Phones:
Business:
(352) 294-8593
Emails:

Recent news

UF researchers report mixed results in safety study of drugs seen as possible COVID-19 therapeutics

University of Florida College of Pharmacy researchers studying the safety of two classes of drugs touted as potential therapeutics for COVID-19 report mixed results.

UF leadership in the International Society for Pharmacoepidemiology

UF Faculty and alumni took over several leadership roles in the society during the 35th International Conference on Pharmacoepidemiology in Philadelphia.   Along with Dr. Almut Winterstein, Dr. Juan Hincapie-Castillo also…

Study finds moderate reduction carisoprodol use following DEA Schedule IV classification

UF researchers reviewed more than 13 million patients using carisoprodol, a powerful muscle relaxant.

Dr. Josh Brown receives AMCP’s 2019 New Practitioner Award

AMCP gives the award to a member who has made a significant contribution to managed care pharmacy within five years of graduation.