Search results for natural product

Hendrik Luesch, Ph.D., and Yousong Ding, Ph.D., co-authored the study that identified the genes responsible for producing dolastatin 10.

Dean Johnson shares her reflection on the college's heroic response to the COVID-19 pandemic.

A chemical compound made from a type of bacteria discovered in the Florida Keys by a University of Florida pharmacy researcher has shown effectiveness in fighting colon cancer in preclinical experiments. Writing online in the Journal of Pharmacology and Experimental Therapeutics, scientists say the compound — known as largazole because it was first found near...

The 37th Annual Research Showcase featured more than 110 poster presentations, 12 oral presentations and a keynote address from Dr. Angela Kashuba.

A novel strategy developed by UF Health researchers has yielded several promising compounds to fight inflammation and diseases such as colorectal cancer.

1923 The first entering class of 43 students registered for classes in Science Hall, now Flint Hall and Peabody Hall. Townes R. Leigh, Head of the Department of Chemistry, was appointed Director of the School of Pharmacy by President Murphree. The School of Pharmacy offered the Graduate of Pharmacy degree (Ph.G.), the Pharmaceutical Chemist degree...

For selected compounds (by ourselves or in collaboration), we are devising synthetic methods to probe structure–activity relationships (SAR) and to obtain larger quantities of material for biological evaluation, including toxicity, pharmacokinetic and efficacy studies in animal models, which we will carry out in due course. Molecules of interest include largazoles and apratoxins, which we discovered and...

Center for Drug Evaluation and Safety The University of Florida Center for Drug Evaluation and Safety, or CoDES, unites researchers interested in using big data to evaluate drugs and the safety of medications in real-world populations. More than 20 drug safety researchers representing four of the six academic colleges at UF Health are members of...

The April 29 event will highlight the center's ongoing research activities and screening infrastructure.

  Mission The mission of the Center for Natural Products, Drug Discovery and Development, or CNPD3, is to foster early-stage drug discovery by providing the infrastructure, chemical libraries and expertise to screen for disease-relevant targets and for drug-like disease-modifying molecules that modulate target activity. The CNPD3 provides the academic home for the identification of drug leads...