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synthesis through the invention of novel chemical methodologies and strategies and to discover natural product-based chemotherapeutics.
is the pharmacophore of the natural product and liberated during protein-assisted thioester hydrolysis to largazole thiol. We determined that largazole inhibits HDACs in vivo
areas such as natural products, cancer, anti-infectives, drug abuse and pain research. Ph.D. program
professional interests are in the field of pharmacognosy, which is the study of natural products. She received a UF Distinguished Alumnus Award in 2015.
, Ph.D., professor and chair of medicinal chemistry and the Debbie and Sylvia DeSantis Chair in Natural Products Drug Discovery and Development. Her research poster featured two
Wednesday, March 12, from 10 – 11 a.m. in C1-004 Dr. Lowell’s presentation title is “Antibiotic development through natural product modification.”
Wednesday, Oct. 25, from 10 – 11 a.m. in Communicore C1-017 Dr. Kou-San Ju’s presentation is titled “Genomics-Accelerated Discovery and Biosynthesis of Phosphonate Natural Products.”
large-scale or focused synthetic libraries as well as natural products for small molecule modulators of target or pathway activity. Furthermore, dietary components including marine
The virtual event will be held April 22-23 and hosted by the Center for Natural Products, Drug Discovery and Development.
Biosynthesis of Natural Products
