Search results for natural product

Genomic screening of marine cyanobacteria for the detection of targeted secondary metabolite biosynthetic genes has been achieved through fosmid DNA libraries construction using HMW metagenomic DNA isolated from environmental cyanobacterial samples. Conserved enzymatic steps shared by diverse biosynthetic gene clusters are used as starting point for the design of degenerate primers from the corresponding biosynthetic...

A promising medicinal compound discovered in a marine organism by University of Florida pharmacy researchers is showing its versatility against multiple diseases. Having already demonstrated its power as an anti-tumor agent, largazole, produced by a cyanobacterium inhabiting coral reefs, has shown a new potential benefit for treating serious fractures, osteoporosis and other bone diseases, according...

A 14,500-square-foot integrated drug discovery lab will house some of UF’s medicinal chemistry faculty.

Dr. Yousong Ding, an associate professor of medicinal chemistry, contributed to the study that was published in the journal Communications Biology.

With the funding from the Maximizing Investigators’ Research Award, Ding aims to access and expand chemical diversity of microbes through the use of new, innovative strategies.

A UF College of Pharmacy researcher team led by Dr. Hendrik Luesch recently developed a novel molecule based on marine cyanobacteria, Apra S10, to target pancreatic cancer cells.

The 10 medicinal chemistry faculty currently serve as principal investigators on 18 different federally funded grants worth more than $18.4 million.

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