Search results for natural product

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Marine Natural Products Drug Discovery and Development

https://mc.pharmacy.ufl.edu/research/faculty-research-areas/marine-natural-products-drug-discovery-and-development/

Research in the Luesch lab lies at the interface of chemistry and biology and addresses multiple aspects of the drug discovery process ranging from assay development, identification and structure determination of bioactive small molecules with a focus on marine natural products, studies toward their mechanism of action, chemical synthesis and drug development of promising agents, the engineering of their...

Medicinal Chemistry

http://mc.pharmacy.ufl.edu/

The department of medicinal chemistry is located in the University of Florida College of Pharmacy and is an integral part of UF Health. The department has excellent research facilities dedicated to major areas of medicinal chemistry research, and faculty in the department have been highly successful in attracting extramural research support. UF’s Preeminence initiative in...

Members

http://cnpd3.pharmacy.ufl.edu/contacts/#new_tab

 Director: Hendrik Luesch, Ph.D., Debbie and Sylvia DeSantis Chair in Natural Products Drug Discovery and Development Department of Medicinal Chemistry Jane Aldrich, Ph.D. Qi-Yin Chen, Ph.D. Yousong Ding, Ph.D. Robert Huigens III, Ph.D. Margaret O. James, Ph.D. Chenglong Li, Ph.D. Christopher R. McCurdy, Ph.D. Ranjala Ratnayake, Ph.D. Chengguo (Chris) Xing, Ph.D. Department of Pharmaceutics Hartmut Derendorf,...

Microbial Genomics and Biosynthetic Engineering

https://mc.pharmacy.ufl.edu/research/faculty-research-areas/marine-natural-products-drug-discovery-and-development/microbial-genomics-and-biosynthetic-engineering/

Genomic screening of marine cyanobacteria for the detection of targeted secondary metabolite biosynthetic genes has been achieved through fosmid DNA libraries construction using HMW metagenomic DNA isolated from environmental cyanobacterial samples. Conserved enzymatic steps shared by diverse biosynthetic gene clusters are used as starting point for the design of degenerate primers from the corresponding biosynthetic...

New findings on UF marine compound shows versatility, from anti-tumor agent to bone regeneration

A promising medicinal compound discovered in a marine organism by University of Florida pharmacy researchers is showing its versatility against multiple diseases. Having already demonstrated its power as an anti-tumor agent, largazole, produced by a cyanobacterium inhabiting coral reefs, has shown a new potential benefit for treating serious fractures, osteoporosis and other bone diseases, according...

Nicholas Bodor , Ph.D.

Graduate Research Professor Emeritus

Bodor received his B.S./M.S. degree in Organic Chemistry in 1959 at Bolyai University in Transylvania, and his Ph.D. degree in 19…