Search results for natural product

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Discovery of Bioactive Marine Natural Products

https://mc.pharmacy.ufl.edu/research/faculty-research-areas/marine-natural-products-drug-discovery-and-development/discovery-of-bioactive-marine-natural-products/

Approximately half of all current drugs are derived from natural products, demonstrating their potential for drug discovery. The structural diversity and biological activity displayed by natural products may be attributed to a long evolutionary selection process. In our quest for small molecules with biomedical utility for various disease indications we mainly investigate natural products. In...

Marine Natural Products Drug Discovery and Development

https://mc.pharmacy.ufl.edu/research/faculty-research-areas/marine-natural-products-drug-discovery-and-development/

Research in the Luesch lab lies at the interface of chemistry and biology and addresses multiple aspects of the drug discovery process ranging from assay development, identification and structure determination of bioactive small molecules with a focus on marine natural products, studies toward their mechanism of action, chemical synthesis and drug development of promising agents, the engineering of their...

UF medicinal chemists modify sea bacteria byproduct for use as potential cancer drug

University of Florida pharmacy researchers have modified a toxic chemical produced by tiny marine microbes and successfully deployed it against laboratory models of colon cancer. Writing today in ACS Medicinal Chemistry Letters, UF medicinal chemists describe how they took a generally lethal byproduct of marine cyanobacteria and made it more specifically toxic — to cancer...

Nicholas Bodor , Ph.D.

Graduate Research Professor Emeritus

Bodor received his B.S./M.S. degree in Organic Chemistry in 1959 at Bolyai University in Transylvania, and his Ph.D. degree in 19…

Ranjala Ratnayake , Ph.D.

Research Associate Professor

Ranjala Ratnayake, Ph.D., was appointed a research assistant professor in the department of medicinal chemistry at the University…

Hendrik Luesch , Ph.D.

Professor And Chair, Debbie And Sylvia DeSantis Chair In Natural Products Drug Discovery And Development

Hendrik Luesch, Ph.D., a professor of medicinal chemistry, received his Diplom in Chemistry at the University of Siegen (Germany)…