2023 Lake Nona Leadership Council

Are You Ready for the Shark Tank?

The annual Lake Nona Leadership Council meeting provides a unique venue to bring together a multidisciplinary group of pharmaceutical leaders and scientists to exchange ideas and advance drug development and regulatory science.

2023 Lake Nona Leadership Symposium graphic

What Lake Nona Leadership Council Symposium

When March 27-28, 2023

Where UF Research and Academic Center at Lake Nona | 6550 Sanger Road, Orlando, FL 32827


Monday – March 27

12:00 – 1:00PMCheck-in & Registration / Light Lunch
1:00 – 1:05PMWelcome
1:05 – 1:45PMState of the Center
Stephan Schmidt
1:45 – 1:55PMBreak
1:55 – 4:15PMBusiness Meeting
Leadership Council & Faculty Only (Room 234)
4:15 – 5:00PMHotel Check In
5:00PMBus shuttle to social event & dinner
6:00 - 10:00PMSocial event & dinner
10:00PMBus shuttle to hotel

Tuesday – March 28

7:15 – 8:00AMRegistration & Breakfast
8:00 – 8:05AMWelcome
8:05 – 8:35AMState of the College
Dean Peter Swaan
8:35 – 9:05AMHow to use Human on a Chip Systems to Predict PK/PD In Vitro and In Vivo
James Hickman
9:05 – 9:35AMSystems Medicine at UF: Mathematics and Computation for Precision Medicine
Reinhard C. Laubenbacher
9:35 – 10:00AMCoffee Break
10:00 – 12:30PMStudent Presentations
12:30 – 2:30PMLunch & Poster Session
2:30PMWrap-Up Session & Meeting Closure

Shark Tank Presenters

  • Shyam S. Ramesh
    Autosomal Dominant Tubulointerstitial Kidney Disease Progression Model 
  • Gamze Bulut
    Bacterial Gene Knockdown Through siRNA Loaded Eukaryotic Exosomes 
  • Janny Pineiro
    Tiny Organs Pack Big Promises for the Pharma Industry 
  • Anthony Gebhart
    Dosing optimization for voriconazole in patients with aspergillosis 
  • Xue Wu
    Predicting Withdrawal Times of Flunixin in Cattle Following Dermal Exposure Using a PBPK Model 
  • Yi Hua Chiang
    Physiologically based pharmacokinetic model For clinical translation of the major alkaloid of kratom and its active metabolite 
  • Priscila A Yamamoto
    Using physiologically-based pharmacokinetic modeling to build digital twins for personalized dosing in obese and post-bariatric surgery patients 
  • Xuefen Yin
    Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine Nonlinear Pharmacokinetic and its Drug-Drug Interaction Potentials on CYP3A4 and CYP2C9 
  • Dain Chun
    Evaluation of ovulation rate as surrogate endpoint for hormonal contraceptivesefficacy using an integrative meta-analysis approach

Shark Tank Judges

  • Sunny Chapel
  • Parag Garhyan
  • Sandhya Girish
  • Navin Goyal
  • Nastya Kassir
  • Matthew Riggs
  • Monica Rodriguez
  • Stacey Tannenbaum
  • Songmao Zheng

Poster Presenters

Poster numberNameTitle
1Omar ElashkarIntegrating deep learning and digital pathology to study pathological alterations in type 1 diabetes
2Clemence Boivin-ChampeauxDevelopment of a modeling platform for hepatitis B virus
3Huili ChenIntegrating Operational Model of Agonist in Model-Based Meta-Analysis for Assessing Inhibition of Ovulation Rate by Different Progestins
4Yi-Hua ChiangPhysiologically based pharmacokinetic model for clinical translation of the major alkaloid of kratom and its active metabolites
5Churni GuptaQuantitative systems pharmacology modeling of alpha-synuclein pathology in Parkinson's disease
6Sulafa Al Sahlawi Predicting the potential for cannabinoids-drug interactions with major CYP450 using model-based approaches
7Qiran ChenPharmacostatistical analysis of tissue distribution of nanoparticles in tumor-bearing mice
8Ahmed AbulfathiIs the current dosing regimen of ropivacaine administered through erector spinae plane blocks safe?
9Parsshava MehtaDevelopment of Intranasal Physiologically Based Nose to Brain Model and its application to characterize in NeuroEPO absorption via nasal route and distribution to lumbar CSF in healthy non-human primates (Cynomolgus monkey)
10Mohammed AlmoslemPharmacokinetic and pharmacodynamic modeling of acetaminophen and ibuprofen to evaluate the time to patent ductus arteriosus closure in preterm neonates
11Leandro PippaLeveraging PBPK modeling to explore the effect of gastric bypass in omeprazole enantioselective pharmacokinetics
12Nicholas WaddingtonAutomatic segmentation of pancreatic islets on whole slide images
13Leyanis RodriguezLeveraging PBPK DDI application to enlighten the mechanisms of the interaction between phenytoin and omeprazole and potential impact in epileptic patients
14Malek Hussein HajjawiDevelopment of a Population Pharmacokinetic Model for Oxytetracycline in Sheep Using a Nonlinear Mixed Effects Approach
15Deok Yong YoonOptimizing clinical trials for Duchenne muscular dystrophy using multivariate disease progression models that bridge a functional endpoint and MRI relaxography of five leg muscles
16Nitin CharbeUnlocking the complications of Oral Absorption: Innovative PBPK Modeling Approach to Predict Food Effect on Weakly Basic
17Mai AbdelmageedPopulation PK/PD modeling of salicylic acid in pregnancy