2023 Lake Nona Leadership Council
Are You Ready for the Shark Tank?
The annual Lake Nona Leadership Council meeting provides a unique venue to bring together a multidisciplinary group of pharmaceutical leaders and scientists to exchange ideas and advance drug development and regulatory science.
What Lake Nona Leadership Council Symposium
When March 27-28, 2023
Where UF Research and Academic Center at Lake Nona | 6550 Sanger Road, Orlando, FL 32827
Agenda
Monday – March 27
| Time | Event |
|---|---|
| 12:00 – 1:00PM | Check-in & Registration / Light Lunch |
| 1:00 – 1:05PM | Welcome |
| 1:05 – 1:45PM | State of the Center Stephan Schmidt |
| 1:45 – 1:55PM | Break |
| 1:55 – 4:15PM | Business Meeting Leadership Council & Faculty Only (Room 234) |
| 4:15 – 5:00PM | Hotel Check In |
| 5:00PM | Bus shuttle to social event & dinner |
| 6:00 - 10:00PM | Social event & dinner |
| 10:00PM | Bus shuttle to hotel |
Tuesday – March 28
| Time | Event |
|---|---|
| 7:15 – 8:00AM | Registration & Breakfast |
| 8:00 – 8:05AM | Welcome |
| 8:05 – 8:35AM | State of the College Dean Peter Swaan |
| 8:35 – 9:05AM | How to use Human on a Chip Systems to Predict PK/PD In Vitro and In Vivo James Hickman |
| 9:05 – 9:35AM | Systems Medicine at UF: Mathematics and Computation for Precision Medicine Reinhard C. Laubenbacher |
| 9:35 – 10:00AM | Coffee Break |
| 10:00 – 12:30PM | Student Presentations |
| 12:30 – 2:30PM | Lunch & Poster Session |
| 2:30PM | Wrap-Up Session & Meeting Closure |
Shark Tank Presenters
- Shyam S. Ramesh
Autosomal Dominant Tubulointerstitial Kidney Disease Progression Model - Gamze Bulut
Bacterial Gene Knockdown Through siRNA Loaded Eukaryotic Exosomes - Janny Pineiro
Tiny Organs Pack Big Promises for the Pharma Industry - Anthony Gebhart
Dosing optimization for voriconazole in patients with aspergillosis - Xue Wu
Predicting Withdrawal Times of Flunixin in Cattle Following Dermal Exposure Using a PBPK Model
- Yi Hua Chiang
Physiologically based pharmacokinetic model For clinical translation of the major alkaloid of kratom and its active metabolite - Priscila A Yamamoto
Using physiologically-based pharmacokinetic modeling to build digital twins for personalized dosing in obese and post-bariatric surgery patients - Xuefen Yin
Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine Nonlinear Pharmacokinetic and its Drug-Drug Interaction Potentials on CYP3A4 and CYP2C9 - Dain Chun
Evaluation of ovulation rate as surrogate endpoint for hormonal contraceptivesefficacy using an integrative meta-analysis approach
Shark Tank Judges
- Sunny Chapel
- Parag Garhyan
- Sandhya Girish
- Navin Goyal
- Nastya Kassir
- Matthew Riggs
- Monica Rodriguez
- Stacey Tannenbaum
- Songmao Zheng
Poster Presenters
| Poster number | Name | Title |
|---|---|---|
| 1 | Omar Elashkar | Integrating deep learning and digital pathology to study pathological alterations in type 1 diabetes |
| 2 | Clemence Boivin-Champeaux | Development of a modeling platform for hepatitis B virus |
| 3 | Huili Chen | Integrating Operational Model of Agonist in Model-Based Meta-Analysis for Assessing Inhibition of Ovulation Rate by Different Progestins |
| 4 | Yi-Hua Chiang | Physiologically based pharmacokinetic model for clinical translation of the major alkaloid of kratom and its active metabolites |
| 5 | Churni Gupta | Quantitative systems pharmacology modeling of alpha-synuclein pathology in Parkinson's disease |
| 6 | Sulafa Al Sahlawi | Predicting the potential for cannabinoids-drug interactions with major CYP450 using model-based approaches |
| 7 | Qiran Chen | Pharmacostatistical analysis of tissue distribution of nanoparticles in tumor-bearing mice |
| 8 | Ahmed Abulfathi | Is the current dosing regimen of ropivacaine administered through erector spinae plane blocks safe? |
| 9 | Parsshava Mehta | Development of Intranasal Physiologically Based Nose to Brain Model and its application to characterize in NeuroEPO absorption via nasal route and distribution to lumbar CSF in healthy non-human primates (Cynomolgus monkey) |
| 10 | Mohammed Almoslem | Pharmacokinetic and pharmacodynamic modeling of acetaminophen and ibuprofen to evaluate the time to patent ductus arteriosus closure in preterm neonates |
| 11 | Leandro Pippa | Leveraging PBPK modeling to explore the effect of gastric bypass in omeprazole enantioselective pharmacokinetics |
| 12 | Nicholas Waddington | Automatic segmentation of pancreatic islets on whole slide images |
| 13 | Leyanis Rodriguez | Leveraging PBPK DDI application to enlighten the mechanisms of the interaction between phenytoin and omeprazole and potential impact in epileptic patients |
| 14 | Malek Hussein Hajjawi | Development of a Population Pharmacokinetic Model for Oxytetracycline in Sheep Using a Nonlinear Mixed Effects Approach |
| 15 | Deok Yong Yoon | Optimizing clinical trials for Duchenne muscular dystrophy using multivariate disease progression models that bridge a functional endpoint and MRI relaxography of five leg muscles |
| 16 | Nitin Charbe | Unlocking the complications of Oral Absorption: Innovative PBPK Modeling Approach to Predict Food Effect on Weakly Basic |
| 17 | Mai Abdelmageed | Population PK/PD modeling of salicylic acid in pregnancy |