Center for Pharmacogenomics and Precision Medicine

Center for Pharmacogenetics and Precision Medicine banner

Research in the Center for Pharmacogenomics and Precision Medicine spans from mechanistic studies to multi-omic approaches to elucidate genetic contributions to drug response. Center investigators collaborate with investigators across the University of Florida and other institutions, both nationally and internationally, to ensure innovation in this cutting-edge science. The center also supports the UF Health Precision Medicine Program through the translation of pharmacogenomic research findings into patient care and examining outcomes with genotype-guided therapies.

PGX Center Stats_v2


Our mission is to facilitate precision medicine by improving patient outcomes through optimization of efficacy and limiting toxicity of drug therapy. This is accomplished through research, teaching and service focused on genetically-guided drug therapy decision making, drug discovery and drug development.

Goals


Center Leadership

Cavallari Cooper DeHoff Langaee

Larisa Cavallari, Pharm.D., FCCP, BCPS
Director of the Center for Pharmacogenomics and Precision Medicine

Rhonda Cooper-DeHoff, Pharm.D., M.S., FCCP, FACC, FAHA
Associate Director of the Center for Pharmacogenomics and Precision Medicine

Taimour Langaee, MSPH, Ph.D.
Director of the Genotyping Core Laboratory

Meet Our Faculty

 

Areas of Research

  • Genetic variability influencing:
    • Effectiveness of cardiovascular drugs
    • Dose requirements of warfarin
    • Opiate effectiveness and toxicity
    • Cancer treatment outcomes
    • Cardiotoxic response to cancer treatments (Cardio-Oncology)
    • Adverse drug response to antiresorptive drugs
    • Response to pulmonary hypertension drug therapy
    • Response to treatment for HIV and other infectious diseases
    • Drug transporter activity
    • Drug metabolism enzyme activity and expression
  • Outcomes with clinical implementation of genotype-guided therapy

Jatinder Lamba

 

Contact Us

Center for Pharmacogenomics and Precision Medicine
University of Florida College of Pharmacy
P.O. Box 100486
Gainesville, FL 32610

lcavallari@cop.ufl.edu
352-273-5283

Genotyping Core Laboratory
Center for Pharmacogenomics and Precision Medicine
Taimour Y. Langaee, MSPH, Ph.D.
Research Associate Professor

langaee@cop.ufl.edu
352-273-6357