Search results for natural product

A mutual research interest brings together College of Pharmacy alumna and supporter Debbie DeSantis and Dr. Hendrik Luesch in search of cyanobacteria in the Florida Keys

The April 29 event will highlight the center's ongoing research activities and screening infrastructure.

Natural Product Reports is the Royal Society of Chemistry’s journal for publication of reviews in all areas of natural products chemistry, including biosynthesis, chemical biology, pharmacology and organic synthesis.

A two-year, $400,000 grant from the National Institute on Alcohol Abuse and Alcoholism, or NIAAA, will allow University of Florida College of Pharmacy researchers to study alcohols' effects on relationships.

Hendrik Luesch, Ph.D., the Debbie and Sylvia DeSantis Chair in Natural Products Drug Discovery and Development in the UF College of Pharmacy, was one of two faculty named as the UF Foundation 2014 Preeminence Term Professors. Now in its second year, the University of Florida Foundation’s Preeminence Term Professorship program supports UF’s Preeminence goals. Each...

University of Florida pharmacy researchers have identified novel drug targets and a new screening method for drugs affecting the signaling pathways in colorectal cancer.

  Mission The mission of the Center for Natural Products, Drug Discovery and Development, or CNPD3, is to foster early-stage drug discovery by providing the infrastructure, chemical libraries and expertise to screen for disease-relevant targets and for drug-like disease-modifying molecules that modulate target activity. The CNPD3 provides the academic home for the identification of drug leads...

Genomic screening of marine cyanobacteria for the detection of targeted secondary metabolite biosynthetic genes has been achieved through fosmid DNA libraries construction using HMW metagenomic DNA isolated from environmental cyanobacterial samples. Conserved enzymatic steps shared by diverse biosynthetic gene clusters are used as starting point for the design of degenerate primers from the corresponding biosynthetic...

Research Assistant Professors           Qi-Yin Chen, Ph.D. (Total Synthesis) Research Assistant Professor Ph.D. Organic Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China M.S. Applied Chemistry, Central South University, Changsha, China B.S. Chemistry, Henan Normal University, Xinxiang, China chenqyufl@ufl.edu Ranjala Ratnayake, Ph.D. (Natural Products Chemistry) Research Assistant Professor & Assistant...

Research in the Luesch lab lies at the interface of chemistry and biology and addresses multiple aspects of the drug discovery process ranging from assay development, identification and structure determination of bioactive small molecules with a focus on marine natural products, studies toward their mechanism of action, chemical synthesis and drug development of promising agents, the engineering of their...