Search results for natural product

The virtual event will be held April 22-23 and hosted by the Center for Natural Products, Drug Discovery & Development.

, identification and structure determination of bioactive small molecules with a focus on marine natural products, studies toward their mechanism of action, chemical synthesis and drug

Approximately half of all current drugs are derived from natural products, demonstrating their potential for drug discovery. The structural diversity and biological activity

Natural Product Reports is the Royal Society of Chemistry’s journal for publication of reviews in all areas of natural products chemistry, including biosynthesis, chemical biology, pharmacology and organic synthesis.

of compound available for characterization studies is an additional fundamental concern in natural products drug discovery, particularly if the structural complexity precludes

. Researchers tested the natural products in multiple cell-based and animal models and found activation of a signaling pathway responsible for fighting off inflammation

Dr. Hendrik Luesch and a team of researchers have discovered a novel marine natural product that binds to a new site of tubulin, an important target for cancer drugs.

expression” Nature Cell Biol. 2010, 12, 758–767. Luesch, H.; Abreu, P. “A natural products approach to drug discovery: probing modes of action of antitumor agents by genome-scale

, Ph.D., a professor and chair of medicinal chemistry and the Debbie and Sylvia DeSantis Chair in Natural Products Drug Discovery and Development. “In an era when competition