Search results for natural product

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New findings on UF marine compound shows versatility, from anti-tumor agent to bone regeneration

A promising medicinal compound discovered in a marine organism by University of Florida pharmacy researchers is showing its versatility against multiple diseases. Having already demonstrated its power as an anti-tumor agent, largazole, produced by a cyanobacterium inhabiting coral reefs, has shown a new potential benefit for treating serious fractures, osteoporosis and other bone diseases, according...

UF medicinal chemists modify sea bacteria byproduct for use as potential cancer drug

University of Florida pharmacy researchers have modified a toxic chemical produced by tiny marine microbes and successfully deployed it against laboratory models of colon cancer. Writing today in ACS Medicinal Chemistry Letters, UF medicinal chemists describe how they took a generally lethal byproduct of marine cyanobacteria and made it more specifically toxic — to cancer...

Exploring new depths in drug discovery

A mutual research interest brings together College of Pharmacy alumna and supporter Debbie DeSantis and Dr. Hendrik Luesch in search of cyanobacteria in the Florida Keys

UF Drug Discovery Symposium

The College of Pharmacy’s Center for Natural Products, Drug Discovery and Development, or CNPD3, will host its inaugural UF Drug Discovery Symposium on April 29 at the Harrell Medical Education Building. The event will highlight the CNPD3’s ongoing research activities and screening infrastructure and invite other UF researchers with an interest in drug discovery and...

Relevant Publications

Genome-Wide Screening for Target ID and Validation: Teo, H.; Ghosh, S.; Luesch, H.; Ghosh, A.; Wong, E. T.; Malik, N.; Orth, A.; de Jesus, P.; Perry, A. S.; Oliver, J. D.; Tran, N. L.; Speiser, L. J.; Wong, M.; Saez, E.; Schultz, P.; Chanda, S. K.; Verma, I. M.; Tergaonkar, V. “Telomere-independent Rap1 is an...

Dr. Hendrik Luesch appointed to Natural Product Reports’ editorial board

Natural Product Reports is the Royal Society of Chemistry’s journal for publication of reviews in all areas of natural products chemistry, including biosynthesis, chemical biology, pharmacology and organic synthesis.