Search results for natural product

Showing 1 - 10 of 63 results

Dr. Hendrik Luesch appointed to Natural Product Reports’ editorial board

http://mc.pharmacy.ufl.edu/2018/01/18/dr-hendrik-luesch-appointed-to-natural-product-reports-editorial-board/

Natural Product Reports is the Royal Society of Chemistry’s journal for publication of reviews in all areas of natural products chemistry, including biosynthesis, chemical biology, pharmacology and organic synthesis.

Center for Natural Products, Drug Discovery and Development (CNPD3)

http://cnpd3.pharmacy.ufl.edu/

  Mission The mission of the Center for Natural Products, Drug Discovery and Development, or CNPD3, is to foster early-stage drug discovery by providing the infrastructure, chemical libraries and expertise to screen for disease-relevant targets and for drug-like disease-modifying molecules that modulate target activity. The CNPD3 provides the academic home for the identification of drug leads...

Discovery of Bioactive Marine Natural Products

https://mc.pharmacy.ufl.edu/research/faculty-research-areas/marine-natural-products-drug-discovery-and-development/discovery-of-bioactive-marine-natural-products/

Approximately half of all current drugs are derived from natural products, demonstrating their potential for drug discovery. The structural diversity and biological activity displayed by natural products may be attributed to a long evolutionary selection process. In our quest for small molecules with biomedical utility for various disease indications we mainly investigate natural products. In...

Marine Natural Products Drug Discovery and Development

https://mc.pharmacy.ufl.edu/research/faculty-research-areas/marine-natural-products-drug-discovery-and-development/

Research in the Luesch lab lies at the interface of chemistry and biology and addresses multiple aspects of the drug discovery process ranging from assay development, identification and structure determination of bioactive small molecules with a focus on marine natural products, studies toward their mechanism of action, chemical synthesis and drug development of promising agents, the engineering of their...

UF medicinal chemists modify sea bacteria byproduct for use as potential cancer drug

University of Florida pharmacy researchers have modified a toxic chemical produced by tiny marine microbes and successfully deployed it against laboratory models of colon cancer. Writing today in ACS Medicinal Chemistry Letters, UF medicinal chemists describe how they took a generally lethal byproduct of marine cyanobacteria and made it more specifically toxic — to cancer...