Karthik Lingineni, M.S., a fourth-year graduate student in the department of pharmaceutics, won a trainee award at the Eleventh American Conference on Pharmacometrics, or ACoP11. Lingineni was one of three trainees honored during the ACoP11 virtual conference, Nov. 9-13.
Lingineni’s award-winning research features the development of a quantitative disease progression model of Duchenne muscular dystrophy, a fatal X-linked genetic disorder that primarily affects males. As Duchenne patients grow older, their muscles degenerate and premature death can occur due to cardiomyopathy or respiratory failure between the ages of 15 and 30. Lingineni’s model uses timed motor function tests as clinical endpoints and able to identify certain demographics and genetic factors that contribute to disease progression. The models may eventually aid in clinical trial design optimization and also the development of new drug therapies to treat Duchenne muscular dystrophy.
The ACoP11 honor is Lingineni’s sixth trainee award this year. In February, he was honored with a best student poster award at the UF College of Pharmacy’s Annual Research Showcase. In March, he received the Jason Morrow and a Presidential Trainee Award from the American Society of Clinical Pharmacology and Therapeutics for having the second highest scoring abstract at the society’s annual meeting. He also received trainee abstract award and Wayne A. Colburn Memorial Award from American College of Clinical Pharmacology. Lingineni is mentored by Stephan Schmidt, Ph.D., F.C.P., an associate professor of pharmaceutics and the Certara Endowed Professor, and Sarah Kim, Ph.D., a research assistant professor of pharmaceutics.