The College of Pharmacy’s Center for Natural Products, Drug Discovery and Development, or CNPD3, will host its inaugural UF Drug Discovery Symposium on April 29 at the Harrell Medical Education Building. The event will highlight the CNPD3’s ongoing research activities and screening infrastructure and invite other UF researchers with an interest in drug discovery and development for collaborative research.
The day-long event will feature three plenary speakers from leading academic drug discovery institutions and ten local session speakers, showcasing CNPD3’s chemical and genomic screening platforms; research in drug design and medicinal chemistry; and translation of genomes to natural products. A poster session by UF graduate students and postdoctoral fellows, followed by an award ceremony for the best posters and a reception, will conclude the day’s events.
Registration
Registration is now closed for this event.
The poster size should not exceed 3’x4′.
Sponsors
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Schedule of Events
8-9:00 a.m. | Registration, continental breakfast and setting up posters |
9-9:15 a.m. | Hendrik Luesch welcome |
Dean Julie Johnson welcome | |
Plenary 1 | |
9:15-10 a.m. | Sumit Chanda – Systems-Based Approaches to Drug Discovery Professor, Infectious and Inflammatory Disease Center, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA |
Session 1 : Chemical and Genomic Screening platform | |
10-10:20 a.m. | Hendrik Luesch – Targeting Cancer Pathways with Marine Natural Products Professor and Chair, Department of Medicinal Chemistry, College of Pharmacy, University of Florida |
10:20-10:40 a.m. | Rob Huigens – Tryptoline-Based Ring Distortion Strategies to Explore New Chemical Space Assistant Professor, Department of Medicinal Chemistry, College of Pharmacy, University of Florida |
10:40-11 a.m. | Alex Grenning – Tunable Synthesis of Medium-Sized Ring-Bearing Terpenoid Cores from Knoevenagel Adducts and Allylic Electrophiles Assistant Professor, Department of Chemistry, College of Liberal Arts and Sciences, University of Florida |
11:00-11:20 a.m. | Keith Choe – Identification of a Nematode Detoxification Response Pathway Inhibitor via screening in C.elegans Assistant Professor, Department of Biology, College of Liberal Arts and Sciences, University of Florida |
10 minute break – refreshments will be served |
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11:30-12:15 p.m. | Plenary 2 |
Bradley Moore – Modern Natural Products Discovery: From Genes to Drug Leads Professor, Center for Marine Biotechnology & Biomedicine, Scripps Institution of Oceanography, La Jolla, CA |
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Session 2 : From Genomes to Natural Products | |
12:15-12:35 p.m. | Yousong Ding – Exploring the Biosynthetic Potential of Microbes and Beyond Assistant Professor, Department of Medicinal Chemistry, College of Pharmacy, University of Florida |
12:35-12:55 p.m. | Valerie de Crécy-Lagard – Discovery of 7-Deazapurine Synthesis Pathways where Secondary Metabolites Intersect with RNA and DNA Modifications Professor, Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida |
12:55-1:15 p.m. | Steven Bruner – Structural Genomic Approaches to Natural Product Biosynthetic Pathways Associate Professor, Department of Chemistry, College of Liberal Arts and Sciences, University of Florida |
1:15-2:15 p.m. Lunch | |
Session 3 : Medicinal Chemistry, Pharmacology and Drug Metabolism | |
2:15-2:35 p.m. | Jane Aldrich – Novel Macrocyclic Tetrapeptides with Opioid Activity: Small changes in structure have significant impact on their in vivo activity Professor, Department of Medicinal Chemistry, College of Pharmacy, University of Florida |
2:35-2:55 p.m. | Brian Law – A New Class of Thiol-Reactive Anticancer Agents Associate Professor, Department of Pharmacology and Therapeutics, College of Medicine, University of Florida |
2:55-3:15 p.m. | Margaret James – Drug Metabolism Insights Professor, Department of Medicinal Chemistry, College of Pharmacy, University of Florida |
3:15-4:45 p.m. | Poster Sessions |
4:45-5:30 p.m. | Plenary 3 |
Layton Smith – Adventures in Academic Drug Discovery Assistant Professor, Director of Drug Discovery, Sanford Burnham Prebys Medical Discovery Institute, Lake Nona, FL |
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5:30-7:30 p.m. Reception and award ceremony | |
6:15-6:30 p.m. | Announcement of Poster Awards |