UF Drug Discovery Symposium

UF Drug Discovery Symposium Logo

The College of Pharmacy’s Center for Natural Products, Drug Discovery and Development, or CNPD3, will host the 2017 UF Drug Discovery Symposium, September 21-22, at the UF Hilton in Gainesville. This year’s symposium will feature an exciting lineup of invited speakers covering most major research institutes across Florida and also includes three plenary lectures from leading scientists at the Dana-Farber Cancer Institute, The National Cancer Institute and The Scripps Research Institute. Additional highlights of the event will include, poster and oral competitions for graduate students and postdoctoral fellows and a closing reception with an awards ceremony on September 22.

Date: September 21-22, 2017

UF Hilton Conference Center

The abstract deadline is Thursday, Aug. 31.
Email abstracts to Nancy Burgos at nburgos@cop.ufl.edu

The registration deadline is Friday, Sept. 8.

Speakers

Plenary Speakers

Eric Fischer, Ph.D., Professor, Dana-Farber Cancer Institute, Boston, Massachusetts

Thomas Kodadek, Ph.D., Professor of Chemistry, The Scripps Research Institute, Jupiter, Florida

David Newman, D.Phil., Retired Chief, Natural Products Branch, National Cancer Institute, Frederick, Maryland & Newman Consulting LLC, Wayne, Pennsylvania

Invited Speakers

John Berry: Department of Chemistry and Biochemistry, Florida International University (FIU)

Bill Baker: Department of Chemistry, University of South Florida (USF)

Valerie Paul: Smithsonian Marine Station (SMS)

Yu Yuan: Department of Chemistry, University of Central Florida (UCF)

Debopam Chakrabarti: Burnett School of Biomedical Sciences, University of Central Florida (UCF)

Predrag Cudic: Department of Chemistry and Biochemistry, Florida Atlantic University (FAU)

Amy Wright: Marine Biomedical and Biotechnology Research at Harbor Branch, Florida Atlantic University (FAU)

Chengguo Xing: Department of Medicinal Chemistry, University of Florida (UF)

Chenglong Li: Department of Medicinal Chemistry, University of Florida (UF)

Christopher McCurdy: Department of Medicinal Chemistry, University of Florida (UF)

Zhongwu Guo: Department of Chemistry, University of Florida (UF)

Tanmay Lele: Department of Chemical Engineering, University of Florida (UF)

Tom Schmittgen: Department of Pharmaceutics, University of Florida (UF)

James Leahy: Department of Chemistry, University of South Florida (USF)

Program

 

Thursday, Sept. 21

11:30 – 1:30 p.m.        Registration and setting up posters (Lunch/snacks will be served)

1:30 – 2 p.m.               Welcome Address and Introductory Remarks:

  • Hendrik Luesch; Director, Center for Natural Products Drug Discovery and Development (CNPD3)
  • Maureen Keller-Wood; Associate Dean for Research and Graduate Education, UF College of Pharmacy
  • Rolf Renne; Associate Director, UF Health Cancer Center (UFHCC)

2 – 2:45 p.m.              Plenary 1: Structural Principles of Small Molecule Mediated Ubiquitin Ligase Targeting

  • Eric Fischer, Assistant Professor, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

BREAK (5 min)

2:50 – 3:50 p.m.         Session 1: Anti-Infective Natural Product Drug Discovery

  • Anti-infective Natural Products from Niche Habitats
    Bill Baker, Professor, Department of Chemistry, University of South Florida
  • In Search of Next Generation Antimalarials
    Debopam Chakrabarti, Professor and Division Head, Molecular Microbiology Division, Burnett School of Biomedical Sciences, University of Central Florida

3:50 – 5:10 p.m.        Graduate Student and Postdoc Session (Moderator, David Newman)

  • Presentations by graduate students and postdoctoral fellows (10 min presentations)

5:15 – 6:45 p.m.        POSTER session (Refreshments will be served)

7:15 p.m.                   SPEAKERS DINNER

Friday, Sept. 22

7 – 8 a.m.                       Registration (Continental breakfast will be served)

8:15 – 9 a.m.                  Plenary 2: A New Way to Target the Proteasome for Cancer Chemotherapy

  • Thomas Kodadek, Professor, Department of Chemistry, The Scripps Research Institute, Florida

9 – 10:30 a.m.               Session 2: Structure-Based and Natural Product-Based Approaches to CNS Disorders and Addiction

  • Identification of a Negative Allosteric Site on Nicotinic Acetylcholine Receptors and its Implication for Drug Design
    Chenglong Li, Professor, Department of Medicinal Chemistry, University of Florida
  • Novel Approach for Peptide-Based Drug Delivery to Brain
    Predrag Cudic, Professor, Department of Chemistry and Biochemistry, Center for Molecular Biology and Biotechnology, Florida Atlantic University
  • Kratom (Mitragyna speciosa) as a Potential Therapy for Opioid Dependence
    Chris McCurdy, Professor, Department of Medicinal Chemistry and Director, UF Translational Drug Development Core, University of Florida

10:30 – 10:45 a.m.         BREAK (Refreshments will be served)

10:45 a.m. – 12:45 p.m. Session 3: Screening of Marine and Terrestrial Natural Products

  • Discovery of Biologically Active Natural Products from the HBOI Enriched Fraction Library
    Amy Wright, Professor, Center of Excellence for Biomedical and Marine Biotechnology Research, Harbor Branch Oceanographic Institute, Florida Atlantic University
  • Biomedical Potential of Benthic Marine Cyanobacteria: A Chemical Ecologist’s Perspective
    Valerie Paul, Head Scientist, Smithsonian Marine Station, Florida
  • Metabolic Profiling of Zebrafish Embryos by High-Resolution Magic Angle Spin (HRMAS) NMR: A Promising Tool for Elucidating Mechanisms and Pathways of Biological Activity
    John Berry, Professor, Department of Chemistry and Biochemistry, Florida International University
  • Dihydromethysticin (DHM) and Flavokawains, Separating Kava’s Lung Cancer Chemopreventive Activity and Hepatotoxic Risk
    Chengguo (Chris) Xing, Professor, Department of Medicinal Chemistry, University of Florida

12:45 – 1:30 p.m.            LUNCH (Boxed lunch will be served)

1:30 – 3 p.m.                   Session 4: Synthesis-Driven Drug Discovery

  • Heterocyclic Antimalarial Compounds with Novel Mode of Action
    Yu Yuan, Assistant Professor, Department of Chemistry, University of Central Florida
  • Synthesis of Anti-infective Agents – Something Old, Something New
    James Leahy, Professor, Department of Chemistry, The Florida Center of Excellence for Drug Discovery and Innovation, University of South Florida
  • New Carbohydrate Antigen-Based Cancer Immunotherapies
    Zhongwu Guo, Professor, Department of Chemistry, University of Florida

3 – 3.15 p.m.                   BREAK (Refreshments will be served)

3:15 – 4:15 pm                Session 5: Assay Development and Screening Initiatives at CNPD3

  • Toward an Explanation for Abnormal Nuclear Morphologies in Cancer
    Tanmay Lele, Professor, Department of Chemical Engineering, University of Florida
  • Drug Screens Targeting The Early Events In The Development Of Pancreas Cancer
    Thomas Schmittgen, Professor, Department of Pharmaceutics, University of Florida

4:15 – 5 p.m.                  Plenary 3: Natural Product-Based Drug Development: Examples of Pitfalls and How They Were Overcome

  • David Newman; Retired Chief, Natural Products Branch at National Cancer Institute & Newman Consulting LLC, Wayne, PA

5 – 7:30 p.m.                 RECEPTION and AWARD CEREMONY

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Hotels

 


Home2Suites [Use Group Code: DDS]
2115 SW 13th Street
Gainesville, FL 32608
352-372-1025
Price Per Room Begins at – $159
Book by: Sept. 7, 2017 for group rate
Rates available Sept. 21-23

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