Regulatory Decision Making

Dr. Lesko’s research interests are applied and clinically-focused in the science of drug development and innovative approaches to supporting regulatory decision-making;  the use of modeling and simulation, as well as genetic and non-genetic biomarkers to address problems and issues surrounding the clinical pharmacology of new and established drugs; and, systems approaches to understanding adverse drug reactions and potential mechanisms of drug-drug interactions in order to improve the benefit-to-risk ratio of medicines