Research

Research in the department of pharmaceutics encompasses studies in pharmacokinetics, quantitative pharmacology, pharmacometrics, pharmaceutical analysis, pharmaceutical biotechnology and drug delivery.

cancer therapy

Thomas Schmittgen

Dr. Schmittgen’s research interests include cancer therapeutics, exosomes as targeted drug delivery systems and the role of noncoding RNAs in cancer initiation and progression.

Schmittgen Slider

Translational Research and Quantitative Clinical Pharmacology

Rodrigo Cristofoletti

Dr. Cristofoletti’s research interests include (patho)physiology-based modeling, in vitro in vivo extrapolation of ADME, biopredictive and microphysiological systems and stem cell technology to quantitatively assess sources of PK and PD variability and inform early stages of drug development.

Rodrigo Cristofoletti

quantitative pharmacology

Natalia De Moraes

Dr. De Moraes’ research interests include quantitative pharmacology approaches in the areas of chronic diseases, special populations, pharmacogenetics and drug-drug-interactions. A major emphasis has been on diabetes, obesity and bariatric surgery effect on drug metabolism and elimination.

Dr. de Moraes

Immune-heterogeneity and cellular diversity

Mei He

Dr. He’s research interests include 3D printing and biomaterials, cancer immunotherapy, extracellular Vesicles and exosomes for biological programming and nanodelivery, microfluidic organ on chip and regenerative and precision therapeutics.

Mei He headshot

Pharmacokinetics of Inhaled glucocorticoids

Guenther Hochhaus

Dr. Hochhaus’ research interests include the relationship between the drug and formulation properties of inhalation drugs, their pharmacokinetic and dynamic properties, and bioequivalence pharmacodynamic effects.

Guenther Hochhaus

Model-informed and AI-powered Drug Development

Sarah Kim

Dr. Kim’s research interests include optimizing clinical trial designs using imaging data through modeling and simulation to inform the rational design of disease prevention and treatment strategies.

Sarah Kim

optimizing pharmacy education

William Cary Mobley

Dr. Mobley’s research interests include application of instructional design principles to optimize student pharmacist learning and the application of critical thinking and reasoning skills to help develop problem-solving abilities.

Cary Mobley

Pharmacometrics and systems pharmacology

Stephan Schmidt

Dr. Schmidt’s research interests include the application of quantitative analysis tools to address clinically relevant research questions in the areas of antimicrobial chemotherapy, pediatrics, diabetes, cardiovascular safety and postmenopausal osteoporosis.

Dr. Stephan Schmidt

Translational Drug Development

Abhisheak Sharma

Dr. Sharma’s research focuses on the in vivo and in vitro preclinical pharmacokinetic studies of new chemical entities and natural products.

Dr. Sharma

Gene and stem cell therapy

Sihong Song

Dr. Song’s research interests include adeno-associated virus, or AAV, vector biology, liver and muscle gene delivery, novel function of alpha 1 antitrypsin, or AAT, AAT deficiency and autoimmune and inflammatory diseases.

Sonal Song

Nanomedicine, Gene & Cellular Therapy

Fan Zhang

Dr. Zhang’s research focuses on developing synthetic nanoplatforms to direct immune cells as “living therapeutics.” To this end, his laboratory integrates materials science, immunology, synthetic biology and translational medicine to create novel nanotherapeutics for controlled modulation of the immune system.

Fan Zhang 600x400

2020-21 research funding

$3.6 million

Faculty in the department of pharmaceutics secured $3.6 million in research funding in 2020-21.

Stephan Schmidt, Ph.D., and his research team use computer simulation models to study drug interactions.

Established in 2011

Center for Pharmacometrics and Systems Pharmacology

Creating a uniquely rigorous and integrative academic translational science program in quantitative clinical pharmacology with a focus on precision medicine.

CPSP