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Center for Natural Products, Drug Discovery and Development (CNPD3)

Dr. Luesh Diving

Video by Chris Bilowich, UF Health News: (click image to view) UF Researcher, Center Director Hendrik Luesch Ph.D., collects marine organisms from Florida Keys that have potential for development into drug therapies and for disease prevention.

Mission

The mission of the University of Florida’s Center for Natural Products, Drug Discovery and Development (CNPD3) is to foster early-stage drug discovery by providing the infrastructure, chemical libraries and expertise to screen for disease-relevant targets and for drug-like disease-modifying molecules that modulate target activity. The chemical focus of the CNPD3 is on unique natural products, and the goal is to fully exploit the biosynthetic as well as therapeutic potential of untapped biodiversity for drug discovery. Candidate compounds could be developed further through interactive chemistry and pharmacology efforts. The CNPD3 provides the academic home for the identification of drug leads and subsequent development campaigns carried out in concert with other biomedical Centers at UF to drive forward preclinical and clinical drug development.

Goals & Objectives

The chemical focus of the CNPD3 is on unique natural products, and the goal is to fully exploit the biosynthetic and therapeutic potential of untapped biodiversity for drug discovery. Candidate compounds are investigated for further development through interactive chemistry and pharmacology efforts.

Education & Training

The Center’s educational objective is to integrate Ph.D. graduate students and postdoctoral fellows whose interdisciplinary interests are focused on drug discovery. CNPD3 efforts encompass all aspects of natural products research, biosynthesis, chemical synthesis, assay development, screening and target identification, as well as drug development.