Medicinal Chemistry

The mission of the department of Medicinal Chemistry is to conduct basic research in chemistry and biochemistry as it relates to drug discovery, to teach these principles in the professional and graduate programs, and to provide service to the scientific community.

The Department of Medicinal Chemistry is located in the College of Pharmacy, and is an integral part of the University of Florida’s Health Science Center. The department has excellent facilities for research in the major areas of Medicinal Chemistry and faculty have been highly successful in attracting extramural research support for the past several years.

Medicinal Chemistry areas of research in drug design, marine natural products and toxicology are a unique blend of the physical and biological sciences. The scope of the field is sufficiently broad to give students with many different science backgrounds a rewarding and challenging program of study. Areas of active interest include drug discovery, organic synthesis of medicinal agents, natural products chemistry, prodrugs, topical drug delivery, peptide chemistry, molecular modeling, drug metabolism and molecular toxicology.

Faculty Spotlight

Jane V. Aldrich, Ph.D.Professor


Student Profile: Marci Smeltz

Meet Our Faculty

The Department of Medicinal Chemistry features many internationally recognized faculty who excel at research and teaching.

Potential Graduate Student Awards

Graduate students in the Department of Medicinal Chemistry have the opportunity to earn many graduate student awards.

Faculty Search

The Department of Medicinal Chemistry in the College of Pharmacy at the University of Florida invites applications for a tenure-track faculty position at the assistant or associate professor level. Candidates should have a record of a strong independent research program in drug discovery and development or demonstrate outstanding potential to build such a program. Faculty hires will also participate in professional and graduate instructional efforts of the college. Area of specialization within medicinal chemistry is open, but should complement the interests of the department and the Center for Natural Products, Drug Discovery and Development and agree with institutional strategies adopted by the University of Florida to foster interdisciplinary research in cancer, infectious diseases, neuroscience and diabetes.


ChemBioChem journal features UF medicinal chemistry researchers as cover art

A University of Florida research team investigating biofilm-eradication has landed on the cover of the Feb. 16 issue of ChemBioChem, a peer-reviewed European journal of chemical biology. Led by Rob Huigens, Ph.D., an assistant professor of medicinal chemistry, the research team discovered new compounds that rapidly eradicate persistent bacteria and biofilms. The compounds could be used as next-generation disinfectants to eradicate biofilms in hospital settings, which lead to drug resistant infections. UF researchers tested the compounds against other compounds known to target and breakdown bacterial membranes and found them to be more potent at killing biofilms and active in rapidly killing persistent bacterial cultures head-to-head with the other membrane-targeting compounds. Assisting Huigens with the research were UF graduate students Yasmeen Abouelhassan and Akash Basak and researcher Hussain Yousaf.

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