The department of medicinal chemistry is located in the University of Florida College of Pharmacy and is an integral part of UF Health. The department has excellent research facilities dedicated to major areas of medicinal chemistry research, and faculty in the department have been highly successful in attracting extramural research support. UF’s Preeminence initiative in drug discovery and development has supported an expansion of the department in focus research areas such as natural products, cancer, anti-infectives, drug abuse and pain research.
The mission of the department of Medicinal Chemistry is to conduct basic research in chemistry and biochemistry as it relates to drug discovery, to teach these principles in the professional and graduate programs and provide service to the scientific community.The department focuses on all aspects of drug design, discovery and development with a unique blend of the physical and biological sciences. The depth and scope of the field offers entering graduate students with many different science backgrounds a rewarding and challenging program of study.
Education and Training
Graduates of the program earn a Ph.D. in pharmaceutical sciences, with a major in Medicinal Chemistry. Recent graduates have secured postdoctoral fellowships and landed faculty positions at major research universities, and they have acquired positions in government agencies and at biotech companies. Several departmental faculty are leading UF Master of Science in Pharmacy online degree programs, including graduate programs in forensic science, pharmaceutical chemistry and clinical toxicology.
Drug Discovery and Development
Departmental faculty have been co-founding startup companies based on UF intellectual property generated in their academic labs. Other preclinical and clinical candidates have been licensed to pharmaceutical and biotech companies.
Student Profile: Marci Smeltz
Meet Our Faculty
The Department of Medicinal Chemistry features many internationally recognized faculty who excel at research and teaching.
Potential Graduate Student Awards
Graduate students in the Department of Medicinal Chemistry have the opportunity to earn many graduate student awards.
The Department of Medicinal Chemistry in the College of Pharmacy at the University of Florida invites applications for a tenure-track faculty position at the assistant or associate professor level. Candidates should have a record of a strong independent research program in drug discovery and development or demonstrate outstanding potential to build such a program. Faculty hires will also participate in professional and graduate instructional efforts of the college. Area of specialization within medicinal chemistry is open, but should complement the interests of the department and the Center for Natural Products, Drug Discovery and Development and agree with institutional strategies adopted by the University of Florida to foster interdisciplinary research in cancer, infectious diseases, neuroscience and diabetes.
ChemBioChem journal features UF medicinal chemistry researchers as cover art
A University of Florida research team investigating biofilm-eradication has landed on the cover of the Feb. 16 issue of ChemBioChem, a peer-reviewed European journal of chemical biology. Led by Rob Huigens, Ph.D., an assistant professor of medicinal chemistry, the research team discovered new compounds that rapidly eradicate persistent bacteria and biofilms. The compounds could be used as next-generation disinfectants to eradicate biofilms in hospital settings, which lead to drug resistant infections. UF researchers tested the compounds against other compounds known to target and breakdown bacterial membranes and found them to be more potent at killing biofilms and active in rapidly killing persistent bacterial cultures head-to-head with the other membrane-targeting compounds. Assisting Huigens with the research were UF graduate students Yasmeen Abouelhassan and Akash Basak and researcher Hussain Yousaf.
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