- Ph.D. Pharmaceutical Sciences, University of Florida, Gainesville, FL, 2008
- B.S. Pharmaceutical Sciences, Friedrich-Alexander University, Erlangen, Germany, 2004
Dr. Schmidt joined the University of Florida as an Assistant Professor at the Center for Pharmacometrics and Systems Pharmacology (CPSP) in Lake Nona (Orlando) in January 2012. He received his B.S. in Pharmaceutical Sciences from the Friedrich-Alexander University in Erlangen, Germany in 2003 and his license to practice as a pharmacist in Germany in 2005. Dr. Schmidt received his Ph.D. from the University of Florida under the supervision of Dr. Hartmut Derendorf in 2008, before completing a 3 year postdoctoral fellowship under the supervision of Prof. Meindert Danhof in the Division of Pharmacology at the Leiden/Amsterdam Center for Drug Research in The Netherlands. During his postdoctoral fellowship, Dr. Schmidt was also a member of the Dutch Top Institute Pharma PK-PD modeling platform.
His research focuses on the application of quantitative (pharmacometrics and systems pharmacology) tools to address clinically relevant research questions in the area of antimicrobial chemotherapy, pediatrics, diabetes, cardiovascular safety and post-menopausal osteoporosis. Dr. Schmidt published his work in more than 10 peer-reviewed journals including Clinical Pharmacology & Therapeutics, CPT: Pharmacometrics & Systems Pharmacology, the British Journal of Clinical Pharmacology, the Journal of Pharmaceutical Sciences, Clinical Pharmacokinetics, and Antimicrobial Agents and Chemotherapy. He also published 3 book chapters on the application of quantitative analysis techniques in various therapeutic areas and is the editor of a book entitled, “Applied Pharmacometrics”, published in 2014 as part of an AAPS series on advancing Pharmaceutical Sciences.
Dr. Schmidt received the Paul Ehrlich Society for Chemotherapy Thesis Award for his work on “Pharmacokinetics/Pharmacodynamics of oxazolidinones and beta-lactams” in 2010, the University of Florida Clinical Translational Science Institute Junior Faculty Pilot Program Award in 2012 as well as the University of Florida Excellence Award for Assistant Professors in 2013.
International Society of Pharmacometrics (ISoP)
American Society for Clinical Pharmacology and Therapeutics (ASCPT)
American Association of Colleges of Pharmacy (AACP)
Paul-Ehrlich Society for Chemotherapy (PEG)
American College of Clinical Pharmacology (ACCP)
American Association of Pharmaceutical Scientists (AAPS)
He published his work in 10 peer reviewed journals including the British Journal of Clinical Pharmacology, the Journal of Pharmaceutical Sciences, Clinical Pharmacokinetics, and Antimicrobial Agents and Chemotherapy. Dr. Schmidt is also the lead author of a book chapter on disease progression analysis, published in 2011 as part of an AAPS series on advancing Pharmaceutical Sciences. In 2010, he received the PEG thesis award for his work on “Pharmacokinetics/Pharmacodynamics of oxazolidinones and beta-lactams.”
- Zheng S, Gaitonde P, Andrew MA, Gibbs MA, Lesko LJ, Schmidt S. Model-based assessment of dosing strategies in children for monoclonal antibodies exhibiting target-mediated drug disposition. CPT Pharmacometrics Syst Pharmacol. 2014; Oct 1;3:e138. doi: 10.1038/psp.2014.38.
- Zheng S, Matzneller P, Zeitlinger M, Schmidt S. Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects. Antimicrob Agents Chemother. 2014; 58: 6675-84.
- Lesko LJ and Schmidt S. Clinical implementation of genetic testing in medicine: a US regulatory science perspective. Br J Clin Pharmacol. 2014; 77: 606-11
- Jiang XL, Zhao P, Barrett JS, Lesko LJ, Schmidt S. Application of physiologically-based pharmacokinetic modeling to predict acetaminophen metabolism & pharmacokinetics in children. CPT Pharmacometrics Syst Pharmacol. 2013 Oct 16;2:e80. doi: 10.1038/psp.2013.55.
- Lesko LJ, Zheng S, Schmidt S. Systems approach in risk assessment. Clin Pharmacol Ther. 2013; 93: 413-424