Lihui Yuan, Pharm.D., Ph.D., R.Ph

Lihui Yuan

Clinical Lecturer

Pharmacodynamics

OFFICE: P1-20A

EMAIL: yuanlh@cop.ufl.edu

PHONE: 352-294-8594

CV: Link to CV

 

Lihui Yuan, Pharm.D., Ph.D., joined the University of Florida College of Pharmacy’s department of pharmacodynamics as a clinical lecturer in 2016. She earned her Pharm.D. from the UF College of Pharmacy and a Ph.D. in molecular genetics and microbiology from UF. Her research interests include diabetes, bacterial pathogenesis and hypertension and cardiovascular disease. In her doctorate program, Yuan researched identifying virulence genes of oral bacteria that are related to pathogenesis of periodontal disease. Her recent research with the department of pathology at UF has focused on establishing associations of viral infections and Type 1 diabetes. Yuan has expressed a passion for teaching and patient care, and she believes that the combination of her understanding of basic science and Pharm.D. training will serve her students well.

Education:

  • Pharm.D., College of Pharmacy, University of Florida
  • Ph.D., Molecular Genetics and Microbiology, University of Florida
  • Master of Agronomy, Horticulture, China Agricultural University, Beijing, China
  • Bachelor of Agronomy, Horticulture, Beijing Agricultural University, Beijing, China

Affiliations:

  • American Society of Consultant Pharmacists

Research Interests:

  • Diabetes
  • Bacterial pathogenesis
  • Hypertension and cardiovascular disease

Publications:

Xia CQ, Peng R, Chernatynskaya AV, Yuan L, Carter C, Valentine J, Sobel E, Atkinson MA, Clare-Salzler MJ. Increased IFN-α-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-α production. J Immunol. 2014 Aug 1;193(3):1024-34.

Xia CQ, Zhang P, Li S, Yuan L, Xia T, Xie C, Clare-Salzler MJ. C-Abl inhibitor imatinib enhances insulin production by β cells: c-Abl negatively regulates insulin production via interfering with the expression of NKx2.2 and GLUT-2. PLoS One. 2014 May 16;9(5):

Verma A, Shan Z, Lei B, Yuan L, Liu X, Nakagawa T, Grant MB, Lewin AS, Hauswirth WW, Raizada MK, Li Q. ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Mol Ther. 2012 Jan;20(1):28-36.

Yamazato M, Ferreira AJ, Yamazato Y, Diez-Freire C, Yuan L, Gillies R, Raizada MK. Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats. J Renin Angiotensin Aldosterone Syst. 2011 Dec;12(4):456-61.

Yamazato Y, Ferreira AJ, Hong KH, Sriramula S, Francis J, Yamazato M, Yuan L, Bradford CN, Shenoy V, Oh SP, Katovich MJ, Raizada MK. Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer. Hypertension. 2009 Aug;54(2):365-71.

Ferreira AJ, Shenoy V, Yamazato Y, Sriramula S, Francis J, Yuan L, Castellano RK, Ostrov DA, Oh SP, Katovich MJ, Raizada MK. Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension. Am J Respir Crit Care Med. 2009 Jun 1;179(11):1048-54.

Yuan L, Rodrigues PH, Bélanger M, Dunn WA Jr, Progulske-Fox A. Porphyromonas gingivalis htrA is involved in cellular invasion and in vivo survival. Microbiology. 2008 Apr;154(Pt 4):1161-9.

Der Sarkissian S, Grobe JL, Yuan L, Narielwala DR, Walter GA, Katovich MJ, Raizada MK. Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology. Hypertension. 2008 Mar;51(3):712-8.

Yuan L, Rodrigues PH, Bélanger M, Dunn W Jr, Progulske-Fox A. The Porphyromonas gingivalis clpB gene is involved in cellular invasion in vitro and virulence in vivo. FEMS Immunol Med Microbiol. 2007 Nov;51(2):388-98.

Díez-Freire C, Vázquez J, Correa de Adjounian MF, Ferrari MF, Yuan L, Silver X, Torres R, Raizada MK. ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR. Physiol Genomics. 2006 Oct 3;27(1):12-9.

Yuan L, Hillman JD, Progulske-Fox A. Microarray analysis of quorum-sensing-regulated genes in Porphyromonas gingivalis. Infect Immun. 2005 Jul;73(7):4146-54.